Search results for "GERMAN"
showing 10 items of 2468 documents
2016
The Dutch Eating Behavior Questionnaire is an internationally widely used instrument assessing different eating styles that may contribute to weight gain and overweight: emotional eating, external eating, and restraint. This study aimed to evaluate the psychometric properties of the 30-item German version of the DEBQ including its measurement invariance across gender, age, and BMI-status in a representative German population sample. Furthermore, we examined the distribution of eating styles in the general population and provide population-based norms for DEBQ scales. A representative sample of the German general population (N = 2513, age ≥ 14 years) was assessed with the German version of t…
Virotherapy in Germany—Recent Activities in Virus Engineering, Preclinical Development, and Clinical Studies
2021
Virotherapy research involves the development, exploration, and application of oncolytic viruses that combine direct killing of cancer cells by viral infection, replication, and spread (oncolysis) with indirect killing by induction of anti-tumor immune responses. Oncolytic viruses can also be engineered to genetically deliver therapeutic proteins for direct or indirect cancer cell killing. In this review—as part of the special edition on “State-of-the-Art Viral Vector Gene Therapy in Germany”—the German community of virotherapists provides an overview of their recent research activities that cover endeavors from screening and engineering viruses as oncolytic cancer therapeutics to their cli…
Supplemented ERA-EDTA Registry data evaluated the frequency of dialysis, kidney transplantation, and comprehensive conservative management for patien…
2021
The aims of this study were to determine the frequency of dialysis and kidney transplantation and to estimate the regularity of comprehensive conservative management (CCM) for patients with kidney failure in Europe. This study uses data from the ERA-EDTA Registry. Additionally, our study included supplemental data from Armenia, Germany, Hungary, Ireland, Kosovo, Luxembourg, Malta, Moldova, Montenegro, Slovenia and additional data from Israel, Italy, Slovakia using other information sources. Through an online survey, responding nephrologists estimated the frequency of CCM (i.e. planned holistic care instead of kidney replacement therapy) in 33 countries. In 2016, the overall incidence of rep…
Requirements Analysis and Specification for a Molecular Tumor Board Platform Based on cBioPortal
2020
Clinicians in molecular tumor boards (MTB) are confronted with a growing amount of genetic high-throughput sequencing data. Today, at German university hospitals, these data are usually handled in complex spreadsheets from which clinicians have to obtain the necessary information. The aim of this work was to gather a comprehensive list of requirements to be met by cBioPortal to support processes in MTBs according to clinical needs. Therefore, oncology experts at nine German university hospitals were surveyed in two rounds of interviews. To generate an interview guideline a scoping review was conducted. For visual support in the second round, screenshot mockups illustrating the requirements …
Analysis of metacarpal V fractures of an interdisciplinary emergency room of an urban German hospital from a forensic viewpoint
2015
Metacarpal V fractures, especially metacarpal neck fractures, are known to the forensic society as a ‘boxer’s fracture’ and are described as being mostly caused by punching an immovable or firm object with force with a closed fist. To our knowledge there is no larger study that examines these fractures under forensic considerations of epidemiology. Our study includes the analysis of metacarpal V fractures in an interdisciplinary, academic and university-affiliated emergency department of an urban hospital over a period of three years. Emergency data sheets were systematically analysed and X-rays evaluated. The results were compared with the existing literature.
How We Forgot Who Discovered DNA: Why It Matters How You Communicate Your Results
2019
One hundred and fifty years ago, a hopeful young researcher reported a recent discovery he had made. Working in the bowels of a medieval castle in the German city of Tübingen, he had isolated a then entirely new type of molecule. This was the birth of a field that would fundamentally change the course of biology, medicine, and beyond. His discovery: DNA. His name: Friedrich Miescher. In this article, the authors try to find answers to the question why-despite the fact that virtually everyone nowadays knows DNA-hardly anyone remembers the man who discovered it. In the history of science, the discovery of DNA was a seminal moment. Why then did it not enter into public memory? Ground-breaking …
Double validation of translated questionnaires in international studies
2018
Background Study questionnaires developed in one country can be translated and used for similar studies in other countries. The main problem of this process is that people speaking different languages can understand the meaning of some questions differently due to disparate mentalities and backgrounds. To avoid a misunderstanding, to perform correct conclusions in accordance to the mentality of each country, and to permit the comparison of results in different countries, the intellectual validation of questionnaires is widely used. The main problem of such a validation is its qualitative nature that can be biased by the subjective approach of the investigator. Therefore, there is a necessit…
Gifted Education in German-Speaking Countries
2011
AbstractThe purpose of this article is to provide the reader with a comprehensive yet detailed account of the current giftedness and gifted education situation in Austria, Germany, and Switzerland. It is concerned with four main research questions: (1) How is ‘giftedness’ defined in German-speaking countries? (2) How are gifted children identified? (3) What gifted education programs are there? (4) What are the empirical findings on these programs?The article is based on relevant journal articles, books, and webpages. The review of each of the topics mentioned above is accompanied by some critical comments.
The creation of goal scoring opportunities in professional soccer. Tactical differences between Spanish La Liga, English Premier League, German Bunde…
2019
The aim of the present study was to compare how goal scoring opportunities emerge in the top four European soccer leagues. The sample included 914 team possessions that led to the creation of goal ...
Let's Talk Biology – Developing a Model for Incorporating English-Speaking Experts into the (Bilingual) Science Classroom
2019
We present an instructional approach to incorporate into biology lessons an exchange of videos between international practicing scientists and secondary-school students. We validated the approach in German school settings in three curricular contexts: genetics, cell biology, and immunology. The participating students (n = 255) were native speakers of German with a background of English as a foreign language. The three participating scientists, English-speaking experts from the United Kingdom and Uganda, were rooted in different fields that were related to the respective curricular topics. We explain how the video exchange model was developed and evaluate students' comments and suggestions f…