Search results for "GERONTOLOGY"

showing 10 items of 2492 documents

Pharmacological Management of Elderly Patients with Asthma–Chronic Obstructive Pulmonary Disease Overlap Syndrome: Room for Speculation?

2016

Asthma and chronic obstructive pulmonary disease (COPD) are two distinct diseases that share a condition of chronic inflammation of the airways and bronchial obstruction. In clinical settings, it is not rare to come across patients who present with clinical and functional features of both diseases, posing a diagnostic dilemma. The overlap condition has been termed asthma–COPD overlap syndrome (ACOS), and mainly occurs in individuals with long-standing asthma, especially if they are also current or former smokers. Patients with ACOS have poorer health-related quality of life and a higher exacerbation rate than subjects with asthma or COPD alone. Whether ACOS is a distinct nosological entity …

medicine.medical_specialtyExacerbationPopulationSettore MED/10 - Malattie Dell'Apparato RespiratorioPulmonary Disease Chronic Obstructive03 medical and health sciences0302 clinical medicinePharmacotherapyAdrenal Cortex HormonesAdministration InhalationPrevalencemedicineHumansPharmacology (medical)030212 general & internal medicineIntensive care medicineeducationAgedAsthmaCOPDeducation.field_of_studyLungbusiness.industryOverlap syndromemedicine.diseaseAsthmaBronchodilator Agentsrespiratory tract diseasesmedicine.anatomical_structure030228 respiratory systemQuality of LifePhysical therapyDrug Therapy CombinationSalmeterolGeriatrics and Gerontologybusinessmedicine.drugDrugs & Aging
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Effects of Square-Stepping Exercise inducing activation of the brain's cognitive function in community-dwelling older Japanese females -Focu…

2015

Aim The purpose of this study was to investigate whether the degree of improvement in cognitive function achieved with an exercise intervention in community-dwelling older Japanese women is affected by the participant's baseline cognitive function and age. Methods Eighty-eight women (mean age: 70.5±4.2 years) participated in a prevention program for long-term care. They completed the Square-Stepping Exercise (SSE) program once a week, 120 minutes/session, for 11 weeks. We assessed participants' cognitive function using 5 cognitive tests (5-Cog) before and after the intervention. We defined cognitive function as the 5-Cog total score and defined the change in cognitive function as the 5-cog …

medicine.medical_specialtyExercise interventionbusiness.industryMean ageCognitionCognitive testCognitionPhysical medicine and rehabilitationIntervention (counseling)Physical therapyHumansMedicineFemaleAnalysis of varianceGeriatrics and GerontologyCognitive declineCognition DisordersbusinessExerciseAgedNippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
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Effectiveness of the PROMUFRA program in pre-frail, community-dwelling older people: A randomized controlled trial.

2020

Abstract This study evaluated the effect of PROMUFRA program on physical frailty, kinanthropometric, muscle function and functional performance variables in pre-frail, community-dwelling older people. Participants (n = 50, 75 ± 7 years) were randomly assigned to two groups: intervention group (IG), and control group (CG). The IG performed multi-component exercise program, focused on high-intensity resistance training (HIRT) combined with self-massage for myofascial release (SMMR) for 12 weeks (2 d.wk−1). Two measurements were performed, at baseline and post-3 months. Participants (n = 43) were analyzed and significant differences were found in group-time interaction for muscle mass (p = 0.0…

medicine.medical_specialtyFrail ElderlyIsometric exerciseIntervention grouplaw.invention03 medical and health sciences0302 clinical medicineExercise programRandomized controlled triallawmedicineHumans030212 general & internal medicineMuscle StrengthLeg pressExerciseAgedFrailtybusiness.industryResistance trainingResistance TrainingMyofascial releaseExercise TherapyPhysical therapyIndependent LivingOlder peoplebusinessGerontology030217 neurology & neurosurgeryGeriatric nursing (New York, N.Y.)
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Multidisciplinary Approach for a Relapsing Goiter with Severe Tracheal Stenosis: A Case Report in an Elderly Patient

2012

Summary Total thyroidectomy is considered the gold standard for thyroid benign pathology treatment. Unfortunately, many partial interventions carried out in the past created many complications due to the tendency of the goiter to relapse and the formation of adherences in the anterior region of the neck. A woman 72 years of age with a relapsing goiter and severe respiratory symptomatology underwent thyroidectomy. After thyroid removal, tracheal stenosis persisted, making the positioning of a T silicon prosthesis (Montgomery’s T-tube) necessary. After 60 days, the prosthesis was replaced with a new made out of the same material but with a larger diameter and a softer consistency, which was r…

medicine.medical_specialtyGoitermedicine.medical_treatmentcomplicationlcsh:GeriatricsDumon prosthesisProsthesisthyroidComplication; Dumon prosthesis; Montgomery prosthesis; Thyroid; ThyroidectomymedicineRespiratory functionMontgomery prosthesibusiness.industryGold standardThyroidDumon prosthesiThyroidectomymedicine.diseaseMontgomery prosthesisTracheal StenosisSurgerySettore MED/18 - Chirurgia Generalelcsh:RC952-954.6medicine.anatomical_structurethyroidectomyGeriatrics and GerontologyComplicationbusinessInternational Journal of Gerontology
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The risk of suicide in healthcare workers in nursing home: An exploratory analysis during COVID-19 epidemic.

2021

In March 2020, the World Health Organization declared the coronavirus disease 19 (COVID‐19) outbreak as global pandemic. Nursing homes were particularly struck by the COVID‐19 outbreak, with some authors considering the COVID‐19 pandemic as the “ground zero” for these structures.

medicine.medical_specialtyHealth PersonnelPoison controlSuicide preventionOccupational safety and health03 medical and health sciences0302 clinical medicineHealth carePandemicmedicineHumansSociologyEpidemics030214 geriatricsbusiness.industryhealthcare workersSARS-CoV-2OutbreakHuman factors and ergonomicsCOVID-19Ground zeroNursing HomesPsychiatry and Mental healthSuicideFamily medicineGeriatrics and GerontologybusinessInternational journal of geriatric psychiatry
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Eight-point compass rose underlay technique in 72 consecutive elderly patients with large incisional hernia

2011

Summary Background Repair of incisional hernia (IH) in the elderly is a challenge for the surgeon. Primary closure is preferable but is not always possible because of high recurrence rates of IH repaired without a prosthesis and/or possible respiratory and cardiovascular complications due to extreme tension of the margins. We report our experience with underlay mesh placement in elderly patients with large IH. Methods A total of 72 patients from January 2003 to December 2009 underwent IH repair involving placement of an intraperitoneal Gore® DualMesh® prosthesis. The prosthesis was first anchored at eight points in a compass rose pattern using a Gore® suture passer and then firmly secured t…

medicine.medical_specialtyIncisional herniamedicine.medical_treatmentHigh-risk elderly patientAdhesion (medicine)lcsh:GeriatricsProsthesisePTFE meshTension-free techniqueAbdominal wallLarge ventral herniaSuture (anatomy)PneumoperitoneumePTFE mesh; High-risk elderly patients; Large ventral hernia; Suture passer; Tension-free techniquemedicineLaparoscopyhigh-risk elderly patientsSuture passermedicine.diagnostic_testbusiness.industrymedicine.diseaseSurgeryDissectionlcsh:RC952-954.6Settore MED/18 - Chirurgia Generalemedicine.anatomical_structureGeriatrics and Gerontologybusiness
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Treatment patterns in older patients with locally advanced head and neck squamous cell carcinoma

2021

OBJECTIVES: We aimed to assess patterns of care delivered to older patients with locally advanced head and neck squamous cell carcinoma (LA-HNSCC), and to analyze the use of geriatric assessment (GA) and assessment of quality of life (QoL).MATERIALS AND METHODS: Members of the head and neck cancer group and the older task force of the European Organisation for Research and Treatment of Cancer (EORTC), members the European Head and Neck Society and members of national groups in Europe were asked to complete a questionnaire about treatment delivered, use of GA, and QoL assessment in older patients with LA-HNSCC.RESULTS: Investigators from 111 centers replied, including 90 (81.1%) academic cen…

medicine.medical_specialtyLocally advancedMEDLINE03 medical and health sciences0302 clinical medicineQuality of lifeSurveys and QuestionnairesmedicineHumans030212 general & internal medicineProspective cohort studyAgedbusiness.industrySquamous Cell Carcinoma of Head and NeckHead and neck cancerCancermedicine.diseaseHead and neck squamous-cell carcinomaCANCERhumanitiesOncologyOropharyngeal CarcinomaHead and Neck Neoplasms030220 oncology & carcinogenesisPhysical therapyCarcinoma Squamous CellQuality of LifeGeriatrics and GerontologybusinessJournal of Geriatric Oncology
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Prognostic value of two geriatric screening tools in a cohort of older patients with early stage Non-Small Cell Lung Cancer treated with hypofraction…

2020

Objectives: To investigatewhether assessmentwith two geriatric screening tools shows a correlationwith clinical outcomes of patients aged 65 years or more, with early-stage Non-Small Cell Lung Cancer (es-NSCLC) treated with hypofractionated stereotactic radiotherapy. Methods: FromMarch 2014 to June 2018we retrospectively evaluated 42 patientswith stage I and II lung tumors. Patients were assessed with Charlson Comorbidity Index (CCI) and G8 screening tool. Median age was 74 years (range, 65–91). Stereotactic radiotherapy was performed with Helical Tomotherapy delivering 50–70 Gray (Gy) in 8–10 fractions. Toxicity was evaluated using Common Terminology Criteria for Adverse Events v4.0 criter…

medicine.medical_specialtyLung Neoplasmsmedicine.medical_treatmentRadiosurgeryChest painTomotherapySettore MED/01 - Statistica Medica03 medical and health sciences0302 clinical medicineCarcinoma Non-Small-Cell LungmedicineHumansProspective Studies030212 general & internal medicineStage (cooking)Adverse effectProspective cohort studyLung cancerEarly Detection of CancerAgedRetrospective StudiesLung cancer Radiation therapy G8 Charlson comorbidity indexbusiness.industryCommon Terminology Criteria for Adverse EventsPrognosismedicine.diseaseTreatment OutcomeOncology030220 oncology & carcinogenesisCohortDose Fractionation RadiationRadiologyGeriatrics and Gerontologymedicine.symptomSettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessJournal of Geriatric Oncology
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Evaluating the effectiveness and risks of oral anticoagulant treatments in multimorbid frail older subjects with atrial fibrillation using the multid…

2018

Background: Previous studies suggested that a different risk of mortality may influence the oral anticoagulant prescription in older patients with atrial fibrillation (AF). Recently, the Multidimensional Prognostic Index (MPI) demonstrated a high grade of accuracy, calibration and feasibility to predict mortality in hospitalized and community-dwelling older people. Prognostic information, as calculated by the MPI, however, is not included in the decision algorithm of treatments in older patients with AF Purpose: The aim of this international multicenter prospective observational study was to evaluate whether a different prognostic profile, as determined by the MPI, is associated with differ…

medicine.medical_specialtyMuldimensional Prognostic IndexPopulationlaw.invention03 medical and health sciencesElderly0302 clinical medicineRandomized controlled triallawInternal medicineAtrial FibrillationmedicineRisk of mortality030212 general & internal medicineMedical prescriptioneducationAnticoagulants; Atrial Fibrillation; Elderly; Frailty; Muldimensional Prognostic Indexeducation.field_of_studyFrailtybusiness.industryAnticoagulantWarfarinAnticoagulantsAtrial fibrillationmedicine.diseaseRelative riskObservational studyGeriatrics and GerontologybusinessGerontology030217 neurology & neurosurgerymedicine.drugEuropean Geriatric Medicine
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Antipsychotic prescription and mortality in hospitalized older persons

2017

Background Recent scientific reports have shown that older persons treated with antipsychotics for dementia-related behavioural symptoms have increased mortality. However, the impact of these drugs prescribed during hospitalization has rarely been assessed. We aimed to investigate whether antipsychotics are associated with an increased risk of mortality during hospitalization and at 3-month follow-up in elderly inpatients. Methods We analyzed data gathered during two waves (2010 and 2012) by the REPOSI (Registro Politerapie Societa Italiana Medicina Interna). All new prescriptions of antipsychotic drugs during hospitalization, whether maintained or discontinued at discharge, were collected,…

medicine.medical_specialtyMultivariate analysis030214 geriatricsbusiness.industrymedicine.medical_treatmentmedicine.diseaseLogistic regression03 medical and health sciencesPsychiatry and Mental health0302 clinical medicineRating scaleNormal cognitionInternal medicinemedicineHaloperidolDementiaGeriatrics and GerontologyMedical prescriptionAntipsychoticbusinessPsychiatryGerontology030217 neurology & neurosurgerymedicine.drugPsychogeriatrics
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