Search results for "GIST"
showing 10 items of 3463 documents
Association between use of novel glucose-lowering drugs and COVID-19 hospitalization and death in patients with type 2 diabetes: a nationwide registr…
2022
Abstract Aims Type 2 diabetes (T2DM) in patients with coronavirus disease-19 (COVID-19) is associated with a worse prognosis. We separately investigated the associations between the use of sodium-glucose cotransporter 2 inhibitors (SGLT2i), glucagon-like peptide-1 receptor agonists (GLP-1 RA), and dipeptidyl peptidase-4 inhibitors (DPP-4i), and the risk of COVID-19 hospitalization and death. Methods and results Patients with T2DM registered in the Swedish National Patient Registry and alive on 1 February 2020 were included. ‘Incident severe COVID-19’ was defined as the first hospitalization and/or death from COVID-19. A modified Poisson regression approach was applied to a 1:1 propensity sc…
CD14+CD16+ monocytes in coronary artery disease and their relationship to serum TNF-α levels
2004
SummaryMonocytes play a central role in the inflammatory disease atherosclerosis. CD14+CD16+ monocytes are considered proinflammatory monocytes, as they have an increased capacity to produce proinflammatory cytokines, such as TNF-α, and are elevated in various inflammatory diseases. We hypothesized that patients with coronary artery disease (CAD) have increased levels of CD14+CD16+ monocytes, and that CD14+CD16+ monocytes are associated with inflammation markers. We investigated CD14+CD16+ monocytes in 247 patients with CAD and 61 control subjects using flow cytometry. In addition serum concentrations of TNF-α, IL-6, and Hs-CRP were assessed. Patients with CAD had higher levels of CD14+CD16…
Inequalities in mortality in small areas of eleven Spanish cities (the multicenter MEDEA project)
2009
The objectives of this study are to identify inequalities in mortality among census tracts of 11 Spanish cities in the period 1996-2003 and to analyse the relationship between these geographical inequalities and socioeconomic deprivation. It is a cross-sectional ecological study where the units of analysis are census tracts. We obtained an index of socioeconomic deprivation and estimated SMR by each census tract using hierarchical Bayesian models which take into account the spatial structure. In the majority of the cities geographical patterns in total mortality were found in both sexes, which were similar to those for the index of socioeconomic deprivation. Among men, four specific causes …
Impact of prehospital delay on mortality in patients with acute myocardial infarction treated with primary angioplasty and intravenous thrombolysis.
2001
Abstract Background In patients with acute myocardial infarction treated with thrombolysis, longer times to treatment are associated with increasingly worse clinical outcome. This relation may be different for treatment with primary angioplasty. Methods We analyzed the pooled data of the German acute myocardial infarction registries Maximal Individual Therapy in Acute Myocardial Infarction (MITRA) and Myocardial Infarction Registry (MIR) to determine the influence of prehospital delays on hospital mortality rates. Primary angioplasty was performed in 1063 patients and thrombolysis in 7552 patients. Results In patients treated with thrombolysis, in-hospital time to treatment was constantly 3…
Puuttuvuuden mallintaminen FINRISKI-tutkimuksessa
2017
Puuttuva tieto on ongelma terveystutkimuksissa, koska tutkimukseen osallistujat ja ei-osallistujat usein eroavat toisistaan. Puuttuvuuden mallintaminen on tärkeää, jotta tuloksia pystyttäisiin korjaamaan ja jatkossa ottamaan mallinnettu puuttuvuus paremmin huomioon tutkimusta suunnitellessa. Myös Kansallinen FINRISKI-tutkimus kärsii puuttuvuudesta, sillä tutkimuksen osallistumisprosentti on laskenut jatkuvasti. Tutkimus on Terveyden ja hyvinvoinnin laitoksen väestötutkimussarja, jonka tavoitteena on seurata kansantauteja ja niiden riskitekijöitä Suomessa sekä tarkkailla suomalaisten terveydentilaa. Tässä työssä pyritään mallintamaan Kansallisen FINRISKI-tutkimuksen puuttuvuus tarkastelemall…
Association of lifestyle habits and academic achievement in Norwegian adolescents: a cross-sectional study
2014
Published version of an article in the journal: BMC Public Health. Also avialable from the publisher: http://dx.doi.org/10.1186/1471-2458-14-829 Background: While healthy lifestyle habits are generally assumed to be important for high academic achievement, there has been little research on this topic among adolescents. The aim of this study was therefore to examine the associations between several lifestyle habits and academic achievement in adolescent girls and boys. Methods: The study included 2,432 Norwegian adolescents, 15–17 years old. A self-report questionnaire was used to assess dietary-, physical activity-, smoking- and snuffing habits and academic achievement. Logistic regression …
Manipulation in late life
2019
AbstractWhile youth language constitutes a well-researched field of study, the linguistic manipulations of old people remain understudied. In an innovative approach, the present paper therefore looks at confusing and allegedly unintelligible narratives and conscious linguistic manipulations, silliness and concealing strategies in language as employed by elderly speakers of Kinyabwisha, Kinande, Kihunde and Kiswahili in Eastern DR Congo. A secret cursing register among Banyabwisha, often accompanied by practices of spitting, is analyzed; I also discuss elderly speakers’ confusing stories narrated to younger people, the use of secret modal particles that are restricted to people of old age, a…
Graphical models for estimating network determinants of multi-destination trips in Sicily
2017
Abstract This paper proposes a two-step approach for analysing the main determinants of multi-destination trip behaviour. It is based on a combination of graphical models and of a multinomial logistic regression model; the aim is to analyse direct and indirect effects of a wide set of tourist- and trip-related characteristics on multi-destination trip behaviour. Empirical data have been derived from a frontier survey of approximately 4000 incoming tourists in Sicily (Italy) at the end of their trip. Results suggest that multi-destination trips depend directly on the length of stay, the number of previous visits and motivation for the trip, and only indirectly on the interview month, travel …
Telemedicine for the acute management of stroke in Burgundy, France: an evaluation of effectiveness and safety
2016
Background In the context of the development of telemedicine in France to address low thrombolysis rates and limited stroke infrastructures, a star-shaped telestroke network was implemented in Burgundy (1.6 million inhabitants). We evaluated the safety and effectiveness of this network for thrombolysis in acute ischemic stroke patients. Methods One hundred and thirty-two consecutive patients who received intravenous thrombolysis during a telemedicine procedure (2012–2014) and 222 consecutive patients who were treated at the stroke center of Dijon University Hospital, France (2011–2012) were included. Main outcomes were the modified Rankin scale (mRS) score and case fatality at 3 months. Com…
Cancer registries and data protection in the age of health digital interoperability in Europe: The perspective of the Italian Network of Cancer Regis…
2022
Population-based cancer registries (PBCRs) are advanced public health systems providing ongoing surveillance through systematic collection, analysis, interpretation, and dissemination of high-quality data on cancer incident cases registered in a defined population residing in a specific geographical area (1, 2). Basically, PBCRs are well equipped for strengthening cancer surveillance, playing a strategic role in making geographic and temporal variation comparisons to highlight cancer epidemics, while assessing the effectiveness of preventive interventions and oncological care (3). Furthermore, many PBCRs provide cancer risk communication to local communities and authorities by using valuabl…