Search results for "GPR"
showing 10 items of 1092 documents
The hedgehog receptor patched is involved in cholesterol transport.
2011
International audience; BACKGROUND: Sonic hedgehog (Shh) signaling plays a crucial role in growth and patterning during embryonic development, and also in stem cell maintenance and tissue regeneration in adults. Aberrant Shh pathway activation is involved in the development of many tumors, and one of the most affected Shh signaling steps found in these tumors is the regulation of the signaling receptor Smoothened by the Shh receptor Patched. In the present work, we investigated Patched activity and the mechanism by which Patched inhibits Smoothened. METHODOLOGY/PRINCIPAL FINDINGS: Using the well-known Shh-responding cell line of mouse fibroblasts NIH 3T3, we first observed that enhancement …
Influence de l'atmosphère gazeuse sur la cinétique de formation du titanate de baryum par réaction solide-solide
1986
International audience; Les études consacrées à la synthèse, par réaction solide-solide, du titanate de baryum (BaTiO3) ont montré l'importance des propriétés physicochimiques des solides initiaux (BaCO3 et TiO2) sur les propriétés du titanate obtenu. Lors de l'élaboration de céramiques diélectriques, il est en effet nécessaire d'éviter la formation de phases intermédiaires (Ba2TiO4, BaTi4O9, ...) qui nuisent à leurs propriétés diélectriques. La présence de ces phases peut être liée à une maîtrise imparfaite des nombreux paramètres influant sur la cinétique de la réaction. Le rôle de deux de ces paramètres : les traitements mécaniques et la nature de l'atmosphère gazeuse, fait l'objet de ce…
Effects of different emulsifiers and refining time on rheological and textural characteristics of compound chocolate
2018
The purpose of this study was to investigate the possibility of producing reduced fat dark compound chocolate in the ball mill refiner and using some selected emulsifiers. The effects of selected emulsifiers including lecithin, Polyglycerol polyricinoleate (PGPR) and citrem in two levels and two refining times on the characteristics such as moisture, particle size, hardness and rheological properties of the samples was examined. Data analysis revealed that the Casson model was appropriate to describe the rheological behavior of the samples containing lecithin and citrem; however, Power law model was appropriate for the samples containing PGPR. The results showed that citrem is the most effe…
Determination of fatty acids and lipid classes in salmon oil by near infrared spectroscopy
2017
International audience; Near-infrared (NIR) spectroscopy was evaluated as a rapid method for the determination of oleic, palmitic, linoleic and linolenic acids as well as omega-3, omega-6, and to predict polyunsaturated, monounsaturated and saturated fatty acids, together with triacylglycerides, diglycerides, free fatty acids and ergosterol in salmon oil. To do it, Partial Least Squares (PLS) regression models were applied to correlate NIR spectra with aforementioned fatty acids and lipid classes. Results obtained were validated in front of reference procedures based on high performance thin layer and gas chromatography. PLS-NIR has a good predictive capability with relative root mean squar…
Clarifying Skills and Competencies in Organisational Decision Making – Perceptions of Finnish Communication Professionals
2017
This paper seeks to better understand the skills and competencies that Public Relations (PR) professionals use in contributing to organisational decision-making processes. The data were collected by interviewing Finnish professionals using thematic semi-structured interviews. Overall, the results highlight a deep understanding of organisation management and decision-making processes. The most important competencies were business understanding and target group oriented thinking. The findings indicate that important skills are related to writing and social media. ‘Regarding personal attributes, interaction and tolerance to criticism were acknowledged as most crucial. The conclusions suggest t…
Ethical Behavior and Organizational Innovation: Analysis of Small and Medium-Sized Enterprises in Latvia
2018
Abstract Innovations can provide small and medium-sized enterprises (SMEs) a significant competitive advantage considering the ambiguous business environment. SMEs may face lower capacity and more constrained funding for long-term investments, however, understanding innovation in a broader sense and looking into organizational structures, behaviors and processes, SMEs have an opportunity to become more competitive. This study analyzes the impact of ethical behavior as a part of an organizational culture on organizational innovation performance in SMEs. Six hundred SMEs in Latvia were surveyed to assess whether employees follow the principles of business ethics in their work and what is the …
Présentation : La sensorialité de l'enfant mangeur, consommateur et patient
2010
ISSN : 0291-0233 ; http://www.medecine-et-enfance.net/
De la perception sensorielle à la consommation du vin. Les consommateurs de vins
2011
PDF à ne pas diffuser; National audience; Appréciation et consommation du vin : un processus d’apprentissage. L’appréciation des boissons alcoolisées n’est pas innée. D’après Rozin et Vollmecke (1986), ces boissons ne sont pas palatables et leur appréciation résulte d’un processus d’apprentissage encore méconnu. L’enquête Vinifhlor-Crego réalisée en 2005 sur 4 036 personnes a montré que 55 % des Français disent ne pas aimer le goût du vin, et pourtant seulement 40 % de ces mêmes Français sont non consommateurs de vin. Cela signifie que 15 % des répondants consomment du vin sans en apprécier le goût. Ce chiffre doit être en réalité plus important car les consommateurs essaient généralement …
Impact flavor compounds in cooked rice cultivars from the Camargue area (France)
2010
International audience; Rice from two scented (Aychade, Fidji) and one nonscented (Ruille) cultivars from Camargue area (France) together with one Asian scented rice (Thai) were cooked and volatile compounds were extracted by dichloromethane/pentane (1;2, v/v) solvent mixture. 40 odorous compounds were noticed during GC-O analysis of the organic extracts, amongst which oct-1-en-3-one and 2-acetyl-1-pyrroline were altmost constantly perceived. Hierarchical cluster analysis (HCA) of perceived odours enabled to distinguish the groups of rice cultivars. 60 compounds were identified and quantified by GC-MS. New odour-active components of cooked rice were detected for the first time including oct…
Impact flavor compounds in cooked rice cultivars from Camargue area (France)
2008
International audience; Efforts have been undertaken for the last decades to promote the production of scented rice cultivars in Camargue, a traditional rice cultivation area in the south of France. Volatile compounds of cooked rice from two scented Camargue rice cultivars (Aychade and Fidji) were analysed and compared to that of a marketed Asian scented rice one (Thai)(1). Additionally volatile analysis from a cooked rice of a non-scented cultivar (Ruille) grown in Camargue was performed. (...)