Search results for "GPT"
showing 4 items of 14 documents
CONVERSAZIONE SULL’USO DELL’INTELLIGENZA ARTIFICIALE NELLA SCUOLA
2023
Di seguito la conversazione con Chatgpt (https://chat.openai.com/chat), a oggi il più avanzato chatbot basato su intelligenza artificiale, intrattenuta in data 4 marzo 2023 sull’uso dell’i.a. nella scuola.
PREVALENCE OF ANGPTL3 AND APOB GENE MUTATIONS IN SUBJECTS WITH COMBINED HYPOLIPIDEMIA
2011
Introduction. Mutations of the ANGPTL3 gene have been found responsible for a novel form of primary hypobetalipoproteinemia (pHBL), the combined hypolipidemia, characterized by low total cholesterol (TC) and low HDL-cholesterol (HDL-C) levels. The aim of this work is to define the role of ANGPTL3 gene as determinant of the combined hypolipidemia phenotype in two large cohorts of 913 American and Italian subjects with primary hypobetalipoproteinemia (TC <5th percentile). Materials and Methods. The cut-offs adopted to define the combined hypolipidemia phenotype were chosen taking into account the TC and HDL-C levels reported in the ANGPTL3 kindred described to date and are as follows: TC leve…
Identification of a novel ANGPTL3 mutation splicing associeted to severe hypobetalipoproteinemia
2012
Introduction. Primary hypobetalipoproteinemia (pHBL) is a monogenic heterogeneous condition inherited as a dominant or recessive trait characterized by total cholesterol (TC) and/or LDL cholesterol (LDL-C) and/or apolipoprotein B (APOB) levels below the 5th percentile of the reference population. Heterozygous APOB gene mutations are responsible for the majority of the dominant pHBL causing the familial hypobetalipoproteinemia (FHBL). Loss-of-function mutations in the PCSK9 gene also cause FHBL. Familial combined hypolipidemia is a recently discovered dyslipidemic phenotype characterized by low levels of TC, triglycerides (TG), LDL-C, and high-density lipoprotein cholesterol (HDL-C). The gen…
Towards Human-Bot Collaborative Software Architecting with ChatGPT
2023
Architecting software-intensive systems can be a complex process. It deals with the daunting tasks of unifying stakeholders' perspectives, designers' intellect, tool-based automation, pattern-driven reuse, and so on, to sketch a blueprint that guides software implementation and evaluation. Despite its benefits, architecture-centric software engineering (ACSE) inherits a multitude of challenges. ACSE challenges could stem from a lack of standardized processes, socio-technical limitations, and scarcity of human expertise etc. that can impede the development of existing and emergent classes of software (e.g., IoTs, blockchain, quantum systems). Software Development Bots (DevBots) trained on la…