Search results for "GRAS"

Efficacy and safety of direct-acting antiviral regimens in HIV/HCV-co-infected patients – French ANRS CO13 HEPAVIH cohort

2017

International audience; Background & aims: There is little data available on the use of new oral direct-acting antiviral (DAA) regimens to treat human immunodeficiency virus and hepatitis C virus (HIV/HCV) co-infected patients in real-life settings. Here, the efficacy and safety of all-oral DAA-based regimens in HIV/HCV-co-infected patients enrolled in the French nationwide ANRS CO13 HEPAVIH observational cohort are reported.Methods: HIV/HCV-co-infected patients enrolled in the ANRS CO13 HEPAVIH observational cohort were included if they began an all-oral DAA-based regimen before 1st May 2015 (12-week regimens) or 1st February 2015 (24-week regimens). Treatment success (SVR12) was defined b…

Misidentification Delusions : prevalence in different types of dementia and validation of a structured Questionnaire

2016

International audience; Misidentification delusions (MDs) are considered relatively rare psychopathologic phenomena that may occur within the context of psychiatric or neurological conditions. The purpose of this study was to assess the prevalence of MD in different types of dementia, correlate the presence of MD with demographic and clinical variables, and validate a specific questionnaire. We examined 146 subjects with Alzheimer disease, 21 with Lewy body dementia, 6 with frontotemporal dementia, and 13 with vascular dementia (subcortical type), who were consecutively enrolled in the study from 2 Memory Clinics. Patients had a mean age of 78.7±6.4 years and an Mini-Mental State Examinatio…

COVID-19 in people living with HIV: Clinical implications of dynamics of the immune response to SARS-CoV-2.

2020

ABSTRACT Background Little evidence on COVID‐19 in people living with HIV (PLWH) is currently available. Material and Methods We reported clinical and viro‐immunological data of all HIV‐positive patients admitted to our centre with COVID‐19 from March 1 to May 12,2020. Results Overall, five patients were included: all were virologically‐suppressed on antiretroviral therapy and CD4+ count was >350 cell/mm3 in all but two patients. Although all patients had evidence of pneumonia on admission, only one developed respiratory failure. SARS‐CoV‐2‐RNA was never detected from nasopharyngeal swabs in two patients, whereas, in the others, viral clearance occurred within a maximum of 43 days. IgG prod…

Associations between weight status and liking scores for sweet, salt and fat according to the gender in adults(The Nutrinet-Santé study)

2015

BACKGROUND/OBJECTIVES: As taste preferences may be associated with obesity, the present study investigated whether obese subjects presented heightened liking for the sensations of sweet, salt and fat.SUBJECTS/METHODS: Liking scores were determined by a questionnaire including 83 items on liking for sweet or fatty foods, and the preferred extent of seasoning with salt, sweet or fat. Data from 46 909 adults included in the French web-based observational cohort of the Nutrinet-Santé study were collected and weighted according to the national population census. Relationships between liking scores and body mass index (BMI) as categorical or linear explanatory variable were assessed separately by…

Studio della connettività tra Ecosistemi Adiacenti in Ambiente Mediterraneo e Tropicale

2008

A GRASP algorithm for constrained two-dimensional non-guillotine cutting problems

2005

This paper presents a greedy randomized adaptive search procedure (GRASP) for the constrained two-dimensional non-guillotine cutting problem, the problem of cutting the rectangular pieces from a large rectangle so as to maximize the value of the pieces cut. We investigate several strategies for the constructive and improvement phases and several choices for critical search parameters. We perform extensive computational experiments with well-known instances previously reported, first to select the best alternatives and then to compare the efficiency of our algorithm with other procedures.

GRASP & evolutionary path relinking for medical image registration based on point matching

2010

Image registration is a very active research area in computer vision. Image registration methods, aim to find a transformation between two images taken under different conditions. Point matching is an image registration approach based on searching for the right pairing of points between the two images. From this matching, the registration transformation can be inferred by means of numerical methods. In this paper, we tackle the medical image registration problem adapting a new advanced hybrid metaheuristic composed by the GRASP and the evolutionary path relinking algorithms, called G&EvPR. The experiments conducted in this work have shown the good performance of G&EvPR compared to similar a…

Advanced Greedy Randomized Adaptive Search Procedure for the Obnoxious p-Median problem

2016

Abstract The Obnoxious p-Median problem consists in selecting a subset of p facilities from a given set of possible locations, in such a way that the sum of the distances between each customer and its nearest facility is maximized. The problem is NP -hard and can be formulated as an integer linear program. It was introduced in the 1990s, and a branch and cut method coupled with a tabu search has been recently proposed. In this paper, we propose a heuristic method – based on the Greedy Randomized Adaptive Search Procedure, GRASP, methodology – for finding approximate solutions to this optimization problem. In particular, we consider an advanced GRASP design in which a filtering mechanism avo…

GRASP with path relinking heuristics for the antibandwidth problem

2010

This article proposes a linear integer programming formulation and several heuristics based on GRASP and path relinking for the antibandwidth problem. In the antibandwidth problem, one is given an undirected graph with n nodes and must label the nodes in a way that each node receives a unique label from the set {1, 2,…,n}, such that, among all adjacent node pairs, the minimum difference between the node labels is maximized. Computational results show that only small instances of this problem can be solved exactly (to optimality) with a commercial integer programming solver and that the heuristics find high-quality solutions in much less time than the commercial solver. © 2010 Wiley Periodic…

A Hybrid Strategic Oscillation with Path Relinking Algorithm for the Multiobjective k-Balanced Center Location Problem

2021

This paper presents a hybridization of Strategic Oscillation with Path Relinking to provide a set of high-quality nondominated solutions for the Multiobjective k-Balanced Center Location problem. The considered location problem seeks to locate k out of m facilities in order to serve n demand points, minimizing the maximum distance between any demand point and its closest facility while balancing the workload among the facilities. An extensive computational experimentation is carried out to compare the performance of our proposal, including the best method found in the state-of-the-art as well as traditional multiobjective evolutionary algorithms.