Search results for "GRAS"

A QM/MM study of the reaction mechanism for the 3′-processing step catalyzed by HIV-1 integrase

2009

Integrase (IN) is one of the three human immunodeficiency virus type 1 enzymes (HIV-1) essential for effective viral replication. This viral enzyme is involved in the integration of HIV DNA into host chromosomal DNA. In this work we have carried out molecular dynamics simulations using a hybrid Quantum Mechanics/Molecular Mechanics (QM/MM) approach to study the reaction mechanism for the 3′-processing step of DNA integration using a model substrate. The results obtained by QM(AM1)/MM and QM(PM3)/MM simulations have been improved by single-point corrections using an ab initio method to describe the quantum subsystem. The results obtained within this computational model can be used to obtain …

Cre-lox: Target Sensitivity Matters

2019

Studying religious music at the grassroots level: a look into the discourse practices of Christian metal bands online

2013

Religious issues are studied in various ways, most prominently by sociologists of religion. This paper suggests that in today’s world of globally intersecting webs of people, places, ideas and action, scholars and readers interested in religion will find themselves benefiting from cross-disciplinary approaches which help them to conceptualize and describe today’s phenomena at different levels. This paper describes how the emerging discipline of the sociology of language and religion may be applied to studying Christian metal bands’ discourse online. Although previous studies give a good idea of the structures, practices and tendencies in and related to Christian metal, little is reported on…

Grasp-specific motor resonance is influenced by the visibility of the observed actor

2016

AbstractMotor resonance is the modulation of M1 corticospinal excitability induced by observation of others' actions. Recent brain imaging studies have revealed that viewing videos of grasping actions led to a differential activation of the ventral premotor cortex depending on whether the entire person is viewed versus only their disembodied hand. Here we used transcranial magnetic stimulation (TMS) to examine motor evoked potentials (MEPs) in the first dorsal interosseous (FDI) and abductor digiti minimi (ADM) during observation of videos or static images in which a whole person or merely the hand was seen reaching and grasping a peanut (precision grip) or an apple (whole hand grasp). Part…

Large-scale Posidonia oceanica restoration in a Site of National Interest using an innovative bio-plastic transplant system

2015

Along the Italian coasts there are many areas affected by industrial activities defined as "Sites of National Interest" (SNI), which require urgent and effective remediation and restoration actions. In the framework of TETIDE project (PON01_03112 www.progettotetide.it)a restoration program was developed in SNI Priolo(Sicily) in response to a dramatic decline and regression of Posidonia oceanicameadow, caused byseveral years of petrochemical industries dumping. In particular, a large scale P. oceanicarestoration plan was carried out in four steps: (1) habitat selection, by calculation of the Preliminary Transplant Suitability Index (PTSI); (2) field assessments and test-transplanting, to eva…

La eficacia de rol, la claridad de rol y el rendimiento en jóvenes futbolistas

2021

El objetivo del trabajo fue doble: 1) Analizar las relaciones entre la eficacia de rol, la claridad de rol y el desempeño efectivo del rol como un indicador subjetivo del rendimiento; y 2) Examinar el papel de la claridad de rol como variable moduladora de la relación entre la eficacia de rol y el rendimiento, ambos objetivos en situaciones de ataque y de defensa en el fútbol. Doscientos noventa y cinco futbolistas varones de entre 12 y 16 años (M = 14.01, DE = 1.09) completaron los cuestionarios que evaluaban las variables del estudio. Los resultados mostraron que aquéllos que percibían una claridad de rol alta también percibían una eficacia de rol alta y un desempeño del rol alto. Además …

Study on Posidonia oceanica (L.) Delile roots growing on different substrata by isto-anatomical and micro-morphological analysis

2016

Posidonia oceanica (L.) Delile grows on different substratum types, ranging from sand, which is easily penetrable by the roots, to rock, in which they are able to enter through crevices (1). In this study a survey was carried out on roots of plagiotropic rhizomes growing on sand (matte), and rock (dolonstone and calcarenite), to assess difference in morphological and anatomical features. In particular, for each substratum, nine rhizomes were randomly sampled by scuba diver at 10 meters of depth. In each rhizome histological and morphometric data (2, 3) were recorded on roots up to the second lateral order. Roots on rock were isolated from their substratum by chemical dissolution. Data analy…

A contribution to the characterization of Ruppia drepanensis (Ruppiaceae), a key species of threatened Mediterranean wetlands

2021

To elucidate the taxonomic status of Ruppia drepanensis Tineo ex Guss. (Alismatales, Ruppiaceae), we performed morphological analysis and DNA barcoding of historical materials (including the lectotype) and fresh samples (including those from a recently discovered population near the locus classicus in Sicily, Italy). We conclude that R. drepanensis is a separate species, closely related to R. spiralis L. ex Dumort., that occurs in temporary inland waters from the western to central sectors of the Mediterranean region. We also highlight the importance of vouchers and the need to link molecular investigations to field, ecological, and morphological investigations.

Signs of local adaptation by genetic selection and isolation promoted by extreme temperature and salinity in the Mediterranean seagrass Posidonia oce…

2023

Adaptation to local conditions is known to occur in seagrasses; however, knowledge of the genetic basis underlying this phenomenon remains scarce. Here, we analysed Posidonia oceanica from six sites within and around the Stagnone di Marsala, a semi-enclosed coastal lagoon where salinity and temperature exceed the generally described tolerance thresholds of the species. Sea surface temperatures (SSTs) were measured and plant samples were collected for the assessment of morphology, flowering rate and for screening genome-wide polymorphisms using double digest restriction-site-associated DNA sequencing. Results demonstrated more extreme SSTs and salinity levels inside the lagoon than the outer…

Rethinking Samir Amin’s legacy and the case for a political organization of the global justice movement

2019

Juego argues that the new Internationale’s “primary organizational function should be the global coordination of actions of progressive grassroots movements from country to country.” He calls for a ‘learning organization,’ where the new Internationale supports “a continuous dialogue between bottom-up and top-down approaches to decision-making.” He sees it as “[a]kin to a global coordinating council” meaning that it works to integrate and synthesize the “varying initiatives, campaigns, and mass actions at all geographical levels of membership” while remaining mindful of the “dialectics between reform and revolution.” The new Internationale must, moreover, be “grounded on a pragmatic understa…