Search results for "GRB"

Detection of GRB 060927 at z = 5.47: Implications for the Use of Gamma-Ray Bursts as Probes of the End of the Dark Ages

2007

We report on follow-up observations of the GRB 060927 using the ROTSE-IIIa telescope and a suite of larger aperture ground-based telescopes. An optical afterglow was detected 20 s after the burst, the earliest rest-frame detection of optical emission from any GRB. Spectroscopy performed with the VLT about 13 hours after the trigger shows a continuum break at lambda ~ 8070 A produced by neutral hydrogen absorption at z~5.6. We also detect an absorption line at 8158 A which we interpret as SiII at z=5.467. Hence, GRB 060927 is the second most distant GRB with a spectroscopically measured redshift. The shape of the red wing of the spectral break can be fitted by a damped Lyalpha profile with a…

Requirement of caveolae microdomains in extracellular signal-regulated kinase and focal adhesion kinase activation induced by endothelin-1 in primary…

1999

Endothelin-1 (ET-1) mitogenic activity in astrocytes is mediated by the activation of the extracellular signal-regulated kinase (ERK) pathway together with the Rho-dependent activation of the focal adhesion kinase (FAK) pathway. To clarify the mechanisms responsible for the coordinate activation of both pathways in the ET-1 signal propagation, the involvement of caveolae microdomains, suggested to play a role in signal transduction, was evaluated. In this study, it is reported that caveolae of primary astrocytes are enriched in endothelin receptor (ETB-R). Furthermore, signaling molecules such as the adaptor proteins Shc and Grb2, and the small G protein Rho, also reside within these microd…

GRB 070311: a direct link between the prompt emission and the afterglow

2007

We present prompt gamma-ray, early NIR/optical, late optical and X-ray observations of the peculiar GRB 070311 discovered by INTEGRAL, in order to gain clues on the mechanisms responsible for the prompt gamma-ray pulse as well as for the early and late multi-band afterglow of GRB 070311. We fitted with empirical functions the gamma-ray and optical light curves and scaled the result to the late time X-rays. The H-band light curve taken by REM shows two pulses peaking 80 and 140 s after the peak of the gamma-ray burst and possibly accompanied by a faint gamma-ray tail. Remarkably, the late optical and X-ray afterglow underwent a major rebrightening between 3x10^4 and 2x10^5 s after the burst …

Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS

2008

The mechanistic understanding of how membrane-embedded sensor kinases recognize signals and regulate kinase activity is currently limited. Here we report structure-function relationships of the multidomain membrane sensor kinase DcuS using solid-state NMR, structural modeling and mutagenesis. Experimental data of an individual cytoplasmic Per-Arnt-Sim (PAS) domain were compared to structural models generated in silico. These studies, together with previous NMR work on the periplasmic PAS domain, enabled structural investigations of a membrane-embedded 40-kDa construct by solid-state NMR, comprising both PAS segments and the membrane domain. Structural alterations are largely limited to prot…

Swift Observations of GRB 070110: An Extraordinary X-Ray Afterglow Powered by the Central Engine

2007

We present a detailed analysis of Swift multi-wavelength observations of GRB 070110 and its remarkable afterglow. The early X-ray light curve, interpreted as the tail of the prompt emission, displays a spectral evolution already seen in other gamma-ray bursts. The optical afterglow shows a shallow decay up to ~2 d after the burst, which is not consistent with standard afterglow models. The most intriguing feature is a very steep decay in the X-ray flux at ~20 ks after the burst, ending an apparent plateau. The abrupt drop of the X-ray light curve rules out an external shock as the origin of the plateau in this burst and implies long-lasting activity of the central engine. The temporal and s…

Protein Phosphorylation by Peroxisome Proliferators: Species-specific Stimulation of Protein Kinases and Its Role in PP-induced Transcriptional Activ…

1996

Zvaigžņotā Debess: 2009, Vasara (204)

2009

Contents: E.Conners. The Trojan Asteroids ; V.Šmēlings. Men on the Moon! ; E.Bervalds. Astronomical Domes and “Sauna” ; Z.Alksne, A.Alksnis. Sakurai’s Object Fails to Escape Own Dust ; Z.Alksne, A.Alksnis. R CrB Stars Surrounded by Dust Clouds ; M.Gills. April Started with Astronomy ; A.Alksnis. First Stamps Dedicated to Astronomy by Latvia’s Post-Office ; I.Pundure. Arturs Balklavs and Astronomy of Latvia (till 1969) ; M.Sudārs. Satellite Collisions – What Threat Do They Pose? ; I.Vilks. Dwarf Planets Names in Latvian ; Announcement on the 2nd International Symposium on Dark-sky Parks: 14-19 September 2009, Slovenia ; A.Andžāns. The Best Way to Fight Darkness Is to Switch on Light (Intervi…

BOOTES observation of GRB 080603B

2012

We report on multicolor photometry of long GRB080603B afterglow from BOOTES-1B and BOOTES-2. The optical afterglow has already been reported to present a break in the optical lightcurve at 0.12 ± 0.2 days after the trigger. We construct the lightcurve and the spectral energy distribution and discuss the nature of the afterglow.

Nuclear protein kinases: still enigmatic components in plant cell signalling

2010

International audience; Plants constantly face changing conditions in their environment. Unravelling the transduction mechanisms from signal perception at the plasma membrane level down to gene expression in the nucleus is a fascinating challenge. Protein phosphorylation, catalysed by protein kinases, is one of the major posttranslational modifications involved in the specificity, kinetic(s) and intensity of a signal transduction pathway. Although commonly assumed, the involvement of nuclear protein kinases in signal transduction is often poorly characterized. In particular, both their regulation and mode of action remain to be elucidated and may lead to the unveiling of new original mechan…

Off-Axis Properties of Short Gamma-Ray Bursts

2005

Based on recent models of relativistic jet formation by thermal energy deposition around black hole-torus systems, the relation between the on- and off-axis appearance of short, hard gamma-ray bursts (GRBs) is discussed in terms of energetics, duration, average Lorentz factor, and probability of observation, assuming that the central engines are remnants of binary neutron star or neutron star-black hole mergers. As a consequence of the interaction with the torus matter at the jet basis and the subsequent expansion of the jets into an extremely low-density environment, the collimated ultrarelativistic outflows possess flat core profiles with only little variation of radially-averaged propert…