Search results for "Gamma"
showing 10 items of 3093 documents
Effects of dead time losses on terrestrial gamma ray flash measurements with the Burst and Transient Source Experiment
2010
[1] Measurements from the Burst and Transient Source Experiment (BATSE) instrument on the Compton Gamma Ray Observatory (CGRO) are the only ones where characteristics of single terrestrial gamma ray flashes (TGFs) have been obtained thus far. However, it has been reported that the measurements suffer from significant dead time losses which complicates the analysis and raises question about earlier BATSE studies. These losses are due to the high-intensity flux combined with limitations of the time resolution of the instrument. Since these losses will affect both the spectrum and the temporal distribution of the individual TGFs, results based on BATSE data need to be revisited, including our …
Misura dell’attività specifica di radionuclidi a lunga vita in alcuni componenti del target di un ciclotrone medicale
2019
La valutazione dell'attività elevata indotta in alcuni componenti del target di un ciclotrone usato per la produzione di radiofarmaci per studi di tomografia a emissione di positroni (PET) è importante per quanto riguarda la protezione dalle radiazioni degli operatori impegnati nella manutenzione, sostituzione e gestione di un target, o suoi componenti. Le attività specifiche sono significativamente elevate da comportare, per scopi radioprotezionistici, una loro classificazione e conservazione in cassaforti schermate in attesa di un loro smaltimento. Tuttavia, dopo alcuni anni, può essere necessario rimuovere le parti più datate per la conservazione di quelle nuove più attive. La fattibilit…
Hepatitis C virus (HCV) and autoimmune liver diseases
1992
Anti-HCV tests were positive in 18–45% of sera from patients with autoimmune chronic active hepatitis. High gammaglobulin levels may result in false positive results, however, some sera show true positivity. PCR testing of such sera is necessary in order to determine whether HCV is directly involved in specific forms of the disease.
Measurement of CP asymmetry in Bs0 → Ds ∓K± decays
2014
Journal of high energy physics 2018(3), 59 (2018). doi:10.1007/JHEP03(2018)059
Asymmetric Michael Addition in Synthesis of β-Substituted GABA Derivatives
2022
γ-Aminobutyric acid (GABA) represents one of the most prolific structural units widely used in the design of modern pharmaceuticals. For example, β-substituted GABA derivatives are found in numerous neurological drugs, such as baclofen, phenibut, tolibut, pregabalin, phenylpiracetam, brivaracetam, and rolipram, to mention just a few. In this review, we critically discuss the literature data reported on the preparation of substituted GABA derivatives using the Michael addition reaction as a key synthetic transformation. Special attention is paid to asymmetric methods featuring synthetically useful stereochemical outcomes and operational simplicity. This research was funded by the National Na…
Simultaneous stimulation of GABA and beta adrenergic receptors stabilizes isotypes of activated adenylyl cyclase heterocomplex
2004
Abstract Background We investigated how the synthesis of cAMP, stimulated by isoproterenol acting through β-adrenoreceptors and Gs, is strongly amplified by simultaneous incubation with baclofen. Baclofen is an agonist of δ-aminobutyric acid type B receptors [GABAB], known to inhibit adenylyl cyclase via Gi. Because these agents have opposite effects on cAMP levels, the unexpected increase in cAMP synthesis when they are applied simultaneously has been intensively investigated. From previous reports, it appears that cyclase type II contributes most significantly to this phenomenon. Results We found that simultaneous application of isoproterenol and baclofen specifically influences the assoc…
Performance of QuantiFERON-TB Gold Plus for detection of latent tuberculosis infection in pregnant women living in a tuberculosis- and HIV-endemic se…
2017
We evaluated the performance of QuantiFERON-TB Gold Plus (QFT-Plus), which includes two Mycobacterium tuberculosis antigen formulations (TB1 and TB2), for detection of latent tuberculosis infection during pregnancy. Eight-hundred-twenty-nine Ethiopian pregnant women (5.9% HIV-positive) were tested with QFT-Plus, with bacteriological sputum analysis performed for women with clinically suspected tuberculosis and HIV-positive women irrespective of clinical presentation. QFT-Plus read-out was categorized according to the conventional cut-off (0.35 IU/ml) for both antigen formulations. In addition, we analysed the distribution of QFT-Plus results within a borderline zone (0.20–0.70 IU/ml), and i…
Non-thermal radiation from a pulsar wind interacting with an inhomogeneous stellar wind
2017
Binaries hosting a massive star and a non-accreting pulsar are powerful non-thermal emitters due to the interaction of the pulsar and the stellar wind. The winds of massive stars are thought to be inhomogeneous, which could have an impact on the non-thermal emission. We study numerically the impact of the presence of inhomogeneities or clumps in the stellar wind on the high-energy non-thermal radiation of high-mass binaries hosting a non-accreting pulsar. We compute the trajectories and physical properties of the streamlines in the shocked pulsar wind without clumps, with a small clump, and with a large one. This information is used to compute the synchrotron and inverse Compton emission fr…
"Table 1" of "Search for supersymmetry in events with photons, bottom quarks, and missing transverse momentum in proton-proton collisions at a centre…
2013
Missing ET distribution.
"Table 4" of "Search for supersymmetry in events with photons, bottom quarks, and missing transverse momentum in proton-proton collisions at a centre…
2013
The expected limit contour in the GLUINO-NEUTRALINO plane.