Search results for "Gas chromatography–mass spectrometry"

showing 10 items of 199 documents

Chemical Composition of the Essential Oil of Zingiber Zerumbet Var. Darcyi

2012

The chemical composition of essential oil obtained by hydrodistillation method from the rhizomes of Z. zerumbet var. darcyi was determined by GC and GC-MS. Thirty-three compounds, accounting for 93.6% of the oil were identified including twenty compounds in minor (0.1-0.6%) and eight in trace (<0.05%) amounts. The main compounds were zerumbone (69.9%) α-humulene (12.9%), humulene epoxide II (2.5%), caryophyllene oxide (1.1%) and camphene (1.9%). In this analysis, it has been found that the variety could be used as an additional new source of natural zerumbone besides Zingiber zerumbet. This is a first report on the analysis of Z. zerumbet var. darcyi oil.

PharmacologybiologyHumuleneTraditional medicinePlant ScienceGeneral Medicinebiology.organism_classificationlaw.inventionRhizomechemistry.chemical_compoundComplementary and alternative medicinechemistryZingiber zerumbetlawDrug DiscoveryBotanyCampheneZingiberaceaeGas chromatography–mass spectrometryChemical compositionEssential oilNatural Product Communications
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Analysis of Essential Oil from Teucrium maghrebinum Greuter et Burdet Growing Wild in Algeria

2009

The chemical composition of the essential oil obtained from aerial parts of Teucrium maghrebinum growing wild in Algeria was analyzed by GC and GC-MS. Among the 66 identified compounds, δ-cadinene (12.7%), germacrene D (11.4%), γ-cadinene (9.5%) and 4-vinyl guaiacol (4.0%) were the most abundant. The oil is strongly characterized by the presence of sesquiterpenes (61.5%), particularly hydrocarbon sesquiterpenes (49.6%).

Pharmacologychemistry.chemical_classificationbiologyChemistryPlant ScienceGeneral Medicinebiology.organism_classificationlaw.inventionTeucriumchemistry.chemical_compoundHydrocarbonComplementary and alternative medicinelawDrug DiscoveryBotanyLamiaceaeGuaiacolGas chromatography–mass spectrometryChemical compositionEssential oilGermacrene DNatural Product Communications
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Environmental and Product Contamination during the Preparation of Antineoplastic Drugs with Robotic Systems

2018

Abstract Background Robotic systems are designed to minimize the exposure to antineoplastic drugs during automated preparation. However, contamination cannot be completely excluded. The aim of the study was to evaluate the contamination with antineoplastic drugs on the working surfaces and on the outer surface of the ready-to-use products (infusion bags and syringes) during automated preparation with different versions of a robot and manual preparation. Methods Surface contamination with platinum (Pt) and 5-fluorouracil (5-FU) was measured by wipe sampling and quantified by voltammetry for Pt and GC-MS for 5-FU. Sampling was performed on pre-defined locations in the working areas before and…

PharmacyRM1-950030226 pharmacology & pharmacygas chromatography/mass spectrometryantineoplastic drugs03 medical and health sciences0302 clinical medicineMedicinePharmacology (medical)Pharmaceutical industryPharmacologyvoltammetryChromatographybusiness.industrysurface contaminationautomated compoundingContaminationwipe samplingRobotic systems030220 oncology & carcinogenesisProduct (mathematics)Antineoplastic DrugsTherapeutics. PharmacologyGas chromatography–mass spectrometryHD9665-9675businessWipe samplingPharmaceutical Technology in Hospital Pharmacy
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Study of the influencing effect of pigments on the photoageing of terpenoid resins used as pictorial media

2006

Abstract Terpenoid resins have been mainly used as components of pictorial varnishes and binding media from ancient times. In such latest instances, the resin is mixed with pigments affecting its physical and chemical properties. A new procedure based on gas chromatography–mass spectrometry (GC/MS) has been applied, in this work, in combination with Fourier transform infrared spectroscopy (FTIR), with the aim of determining the changes undergone by di- and triterpenoid resins employed as components of binding media. The GC/MS method is based on the derivatisation of these resins using trimethylsilylimidazol. Characterization of the main components of the di- and triterpenoid fractions and t…

PhotochemistryInfrared spectroscopyBiochemistryGas Chromatography-Mass SpectrometryAnalytical Chemistrychemistry.chemical_compoundPigmentstomatognathic systemTriterpeneOrganic chemistryFourier transform infrared spectroscopyColoring AgentsCuring (chemistry)Verdigrischemistry.chemical_classificationChromatographyTerpenesOrganic Chemistrytechnology industry and agricultureGeneral Medicinechemistryvisual_artSolventsvisual_art.visual_art_mediumGas chromatographyGas chromatography–mass spectrometryJournal of Chromatography A
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Identification of Volatile Compounds in Blackcurrant Berries: Differences Among Cultivars

2021

Berries of blackcurrant are known to produce a strong flavor. Some previous studies have reported that a given cultivar of blackcurrant can produce berries with a specific profile of volatile compounds. For the Burgundy region in France, the Noir de Bourgogne cultivar is especially important because it is the main ingredient of a liquor with a designation of origin. The aim of the present study was to characterize the volatile fractions of berries from 15 cultivars in order to explore the possibility of using different cultivars for liquor production. The plants were cultivated under the same conditions and harvested in the same year. The volatile fractions of the harvested berries were ana…

PhytochemicalsSPMEPharmaceutical ScienceBiology01 natural sciencesGas Chromatography-Mass SpectrometryArticleAnalytical ChemistryOcimene010104 statistics & probabilitychemistry.chemical_compoundIngredientblackcurrant berriesRibesQD241-4410404 agricultural biotechnologySpecies SpecificityDrug DiscoverycultivarsHumans[CHIM]Chemical SciencesStatistical analysisCultivarvolatile compounds0101 mathematicsPhysical and Theoretical ChemistrySolid Phase MicroextractionFlavorVolatile Organic CompoundsLimonenemultivariate statistical analysesAlcoholic BeveragesOrganic Chemistry04 agricultural and veterinary sciences040401 food scienceCrop Productionchemical profilingFlavoring AgentsHorticulturechemistryChemistry (miscellaneous)FruitTasteMultivariate AnalysisMolecular MedicineFranceGas chromatography–mass spectrometryGC-MSMolecules
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Chemical Composition Analysis, Antimicrobial Activity and Cytotoxicity Screening of Moss Extracts (Moss Phytochemistry)

2015

Mosses have been neglected as a study subject for a long time. Recent research shows that mosses contain remarkable and unique substances with high biological activity. The aim of this study, accordingly, was to analyze the composition of mosses and to screen their antimicrobial and anticancer activity. The total concentration of polyphenols and carbohydrates, the amount of dry residue and the radical scavenging activity were determined for a preliminary evaluation of the chemical composition of moss extracts. In order to analyze and identify the substances present in mosses, two types of extrahents (chloroform, ethanol) and the GC/MS and LC-TOF-MS methods were used. The antimicrobial activ…

PhytochemistryCarbohydratesPharmaceutical ScienceAntineoplastic AgentsApoptosisLC-TOF-MSBryophytaArticleGas Chromatography-Mass SpectrometryAnalytical Chemistrylcsh:QD241-441MiceAnti-Infective Agentsantiradical activitylcsh:Organic chemistryCell Line TumorDrug DiscoveryBotanyAnimalsHumansFood sciencePhysical and Theoretical ChemistrypolyphenolsCell Proliferationamino acidsantimicrobial activitybiologyPlant ExtractsGC/MSOrganic ChemistryBiological activitybiology.organism_classificationAntimicrobialMossTerpenoidRatsChemistry (miscellaneous)PolyphenolMCF-7 CellsextractionMolecular MedicinecytotoxicityGas chromatography–mass spectrometryBacteriaMolecules
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Identification of indigoid compounds present in archaeological Maya blue by pyrolysis-silylation-gas chromatography–mass spectrometry

2014

Abstract A study based on the use of pyrolysis-silylation-gas chromatograpy–mass spectrometry (Py-GC–MS), which aimed to identify indigoid compounds and to clarify the multicomponent composition of Maya blue (MB) pigment, has been carried out. A series of reference compounds and synthetic MB specimens prepared in the laboratory have been analysed by this technique. An analysis of archaeological MB samples from 14 Maya archaeological sites from Mexico and Guatemala has also been performed. The obtained results demonstrate that, in addition to indigo, oxidised species such as dehydroindigo, which is formed as a result of redox processes taking place while preparing the pigment, are present in…

PigmentFuel TechnologySilylationChemistryMaya civilizationvisual_artvisual_art.visual_art_mediumGas chromatography–mass spectrometryMass spectrometryArchaeologyPyrolysisIndigoAnalytical ChemistryJournal of Analytical and Applied Pyrolysis
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GC and GC-–MS Analysis of Volatile Compounds From Ballota nigra subsp. uncinata Collected in Aeolian Islands, Sicily (Southern Italy)

2020

In the present study, the chemical composition of the essential oils from aerial parts of Ballota nigra subsp. uncinata (Bég.) Patzak collected in Sicily was evaluated by gas chromatography (GC) and GC-mass spectrometry. The main components of the oil were ( E)-phytol (20.0%), α-pinene (9.0%), hexahydrofarnesyl acetone (5.7%), and α-selinene (5.1%). Cluster analysis of the essential oil compositions of all the taxa belonging to B. nigra s.l. group was performed.

Plant Science01 natural sciencesessential oillaw.inventionlawDrug DiscoveryBotanyBallota nigraStachydeaeSettore BIO/15 - Biologia FarmaceuticaChemical compositionEssential oilPharmacologyStachydeaeLamiaceaebiology010405 organic chemistryChemistryGeneral MedicineSettore CHIM/06 - Chimica Organicabiology.organism_classification0104 chemical sciences010404 medicinal & biomolecular chemistryComplementary and alternative medicineAeolian processesLamiaceaeGas chromatographyGas chromatography–mass spectrometryBallota nigra subsp. uncinata(E)-Phytol
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Evaluation of the Soil Contamination of Tangier (Morocco) by the Determination of BTEX, PCBs, and PAHs

2009

Benzene, toluene, ethylbenzene, and xylenes (BTEX), twelve polycyclic aromatic hydrocarbons (PAHs) and seven polychlorinated biphenyls (PCBs), were selected as pollutants to evaluate the contamination of soils in the urban and industrial areas of Tangier (Morocco). PAHs and PCBs were determined by gas chromatography-mass spectrometry (GC-MS) after a microwave-assisted extraction (MAE) and gel permeation chromatography (GPC) clean-up. BTEX were directly determined by head-space GC-MS. Results obtained in this study show the presence of high levels of BTEX and PAHs in the soil near the urban waste deposit. However, the analysis of pollutants in the other sampling sites provided comprehensive …

PollutantPollutionHealth Toxicology and Mutagenesismedia_common.quotation_subjectEnvironmental engineeringSoil ScienceBTEXContaminationPollutionEthylbenzeneSoil contaminationchemistry.chemical_compoundchemistryEnvironmental chemistrySoil waterEnvironmental ChemistryGas chromatography–mass spectrometrymedia_commonSoil and Sediment Contamination: An International Journal
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Polycyclic aromatic hydrocarbons (PAHs) in indoor dust matter of Palermo (Italy) area: Extraction, GC–MS analysis,distribution and sources

2008

Abstract Studies on indoor pollution are important since people spend more than 80% of their time indoor environments. In this work the method for PAHs analysis in indoor dust (used as passive sampler) and the results relative to samples collected in the area of Palermo are reported. Dust samples for analysis were collected from 45 indoor environments. Total PAHs concentrations in indoor dusts ranged from 36 to 34 453 μg kg −1  d.w. To correlate indoor and outdoor pollution we analyze, also, the particulate matter and PAHs levels samples collected in four stations. The percentage measured in indoor dusts results more low than that found outside. The values of isomeric ratios for the differe…

PollutionAtmospheric SciencePersistent organic pollutantmedia_common.quotation_subjectExtraction (chemistry)Environmental engineeringParticulatesAnalyse qualitativeSettore CHIM/12 - Chimica Dell'Ambiente E Dei Beni Culturaliindoor dust GCMS PAHsQualitative analysisEnvironmental chemistryEnvironmental scienceGas chromatography–mass spectrometryAnthropogenic factorGeneral Environmental Sciencemedia_common
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