Search results for "Gel"

showing 10 items of 3561 documents

"Se on neliöjuurilaskua se kakskymmentä kertaa kakskymmentä" : tapaustutkimus matemaattisesti taitavien 7-vuotiaiden lasten ajattelusta, RATKO-ongelm…

1999

matematiikkaalkuopetuseriyttäminenRATKO-ongelmanratkaisumenetelmämatemaattinen ajatteluongelmanratkaisu
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Learning research in a laboratory classroom : a reflection on complementarity and commensurability among multiple analytical accounts

2022

With the myriad theories generated through research over the years, a continuing challenge for researchers is to navigate the multitude of theories in order to communicate their research, integrate empirical results, and make progress as a field by building upon empirical research. The Social Unit of Learning project was purposefully designed so that researchers from multiple disciplines with different theoretical perspectives could work together to examine the complexity of the mathematics classroom. In this paper, we reflect on the multiple analytical accounts generated from the project, drawing from the notions of complementarity and commensurability. Two parallel analyses, applying the …

matematiikkaoppiminenoppimisteoriatyläkoululaisetvideo researchteoriatcollaborative problem solvingongelmanratkaisututkimuscomplementarity and commensurabilityyhteisöllinen oppiminenmulti-theoretic research designyear 7 studentsinstructional advocacies
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Mathematics Learning through Arts and Collaborative Problem-Solving : The Princess and the Diamond-Problem

2016

In this paper, we examine a mathematics education course which focused on collaborative mathematical problem solving in art topics. The students of the course were Finnish primary school pre-service teachers. During the course students investigated tessellations, reflected on their experiences and designed workshops for pupils. The course meetings were video recorded. Students’ work contained elements of mathematical problem solving and gave them experiences of working collaboratively. The topic of tessellation was found suitable for this purpose. peerReviewed

matematiikkaoppiminenproblem-solvingartsComputingMilieux_COMPUTERSANDEDUCATIONongelmanratkaisutaidemathematics learning
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Teacher Guidance in Mathematical Problem-Solving Lessons : Insights from Two Professional Development Programs

2019

When implementing a problem-solving lesson, the teacher needs to provide students appropriate guidance during problem solving. This demanding task requires understanding students’ work in progress and giving them necessary help without constraining their thinking. In this article, we share insights from two professional development programs on how teachers guided students’ problem solving and how they reflected on these instances. One of the programs included Finnish pre-service teachers, while the other program included US in-service teachers. We analyzed video-recorded problem-solving lessons from 16 Finnish and 2 US teachers in grades 6–9. We found two themes about teacher guidance of st…

mathematics teachingongelmalähtöinen oppiminenproblem solvingammatillinen kehitysComputingMilieux_COMPUTERSANDEDUCATIONmatematiikanopettajatinquiryopettajankoulutusguidanceteacher education
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Hegel and Hobbes on Institutions and Collective Actions

2004

.  Georg Wilhelm Friedrich Hegel is usually, and rightly, considered the foremost representative of the organistic conception of society. It is only natural to think that his view has nothing in common with the kind of individualistic outlook that dominates our legal and political thinking, and that I myself have tried to defend. I try to show why certain insights of Hegel are potentially important even for individualistic legal and political theories. First, I explicate some of the problems he struggled with, and compare his views with those of Thomas Hobbes. Next, I try to link his views to the modern theories of institutions and of collective action. The antidemocratic ideology expressed…

media_common.quotation_subjectHegelianismCollective actionEpistemologyPoliticsIndividualismAction (philosophy)NothingLawIdeologySociologyLawPopular sovereigntymedia_commonRatio Juris
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What it Means to be a Stranger to Oneself

2009

In adult education there is always a problem of prefabricated and in many respect fixed opinions and views of the world. In this sense, I will argue, that the starting point of radical education should be in the destruction of these walls of belief that people build around themselves in order to feel safe. In this connection I will talk about ‘gentle shattering of identities’ as a problem and a method of radical education. When we as adult educators are trying to gently shatter these solidified identities and pre‐packed ways of being and acting in the world, we are moving in the field of questions that Sigmund Freud tackled with the concepts of ‘de‐personalization’ and ‘de‐realization’. The…

media_common.quotation_subjectSelf-conceptHegelianismCritical pedagogyEducationEpistemologyAdult educationTransformative learningHistory and Philosophy of ScienceCritical theorySociologyPhilosophy of educationSkepticismmedia_commonEducational Philosophy and Theory
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Monoclonal antibody TeM 106 reacts with a tonoplast intrinsic protein of 106 kDa from Brassica oleracea L

1995

A monoclonal antibody, designated TeM 106, that recognizes an intrinsic protein from the vacuole membrane (tonoplast) of cauliflower (Brassica oleracea L. var. botrytis) is described. Mice were immunized with a tonoplast fraction that had been purified from differentiating meristematic cells from the cauliflower head. Hybridomas were generated and screened by means of Enzyme Linked Immuno Sorbent Assays for differential reactivity to tonoplast over non-related proteins (bovine serum albumin). One out of 14 reactive murine clones was selected on the basis of its stability, secretory efficiency, and high affinity of the secreted antibodies. TeM 106 is an IgM which was shown by indirect immuno…

medicine.drug_classBlotting WesternFluorescent Antibody TechniqueMannoseEnzyme-Linked Immunosorbent AssayBrassicaVacuoleMonoclonal antibodyEpitopeMicechemistry.chemical_compoundAntigenAntibody SpecificityConcanavalin AmedicineAnimalsElectrophoresis Gel Two-DimensionalBovine serum albuminPlant ProteinsGel electrophoresisbiologyAntibodies MonoclonalMembrane ProteinsSerum Albumin BovineIntracellular MembranesCell BiologyMolecular biologyMolecular WeightKineticsBiochemistrychemistryVacuolesbiology.proteinElectrophoresis Polyacrylamide GelPlant LectinsAntibodyJournal of Cell Science
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Identification and characterization of a monoclonal antibody to the membrane fatty acid binding protein

1992

A monoclonal antibody to the rat liver membrane fatty acid binding protein (MFABP) was prepared by immunizing mice with purified MFABP isolated from solubilized rat liver plasma membrane proteins by oleate-agarose affinity chromatography technique. The monoclonal antibody K15/6 identified a single 40 kDa protein in rat liver plasma membranes with pI values of 8.5, 8.8 and 9.0, which is identical to the authentic MFABP, but clearly distinct from rat mitochondrial GOT. The antibody K15/6 selectively inhibited cellular influx as well as membrane binding of fatty acids, but not of cholesterol or vitamin E. The same antibody was used in immunofluorescence, ELISA and Western blot analysis to dete…

medicine.drug_classBlotting WesternImmunoblottingBiophysicsFluorescent Antibody TechniqueEnzyme-Linked Immunosorbent AssayNerve Tissue ProteinsFatty Acid-Binding ProteinsMonoclonal antibodyBiochemistryFatty acid-binding proteinCell LineMiceEndocrinologyAffinity chromatographymedicineAnimalsHumanschemistry.chemical_classificationMice Inbred BALB CbiologyMembrane transport proteinTumor Suppressor ProteinsBinding proteinCell MembraneFatty AcidsAntibodies MonoclonalFatty acidMolecular biologyNeoplasm ProteinsRatsLiverchemistryMembrane proteinBiochemistrybiology.proteinElectrophoresis Polyacrylamide GelAntibodyCarrier ProteinsFatty Acid-Binding Protein 7Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism
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New hydrogel matrices containing an anti-inflammatory agent. Evaluation of in vitro release and photoprotective activity.

2002

In the present work. the preparation and characterization of hydrogels based on alpha,beta-polyaspartylhydrazide (PAHy) chemically crosslinked with ethyleneglycol diglycidylether (EGDGE) containing Tolmetin sodium salt, are reported. In particular, these samples have been prepared both as water swellable microparticles and as gels at two different crosslinking degrees. The incorporation of Tolmetin sodium salt in PAHy-EGDGE microparticles has been performed after the crosslinking reaction by a soaking procedure or during the formation of the network. The influence of drug loading procedure on Tolmetin release has been evaluated by performing in vitro release study in simulated gastrointesti…

medicine.drug_classPhotochemistrySodiumBiophysicsSynthetic membranechemistry.chemical_elementSalt (chemistry)BioengineeringIn Vitro TechniquesCrystallography X-RayAnti-inflammatoryHydrogel Polyethylene Glycol DimethacrylateBiomaterialsmedicineOrganic chemistryTolmetinchemistry.chemical_classificationChromatographyAnti-Inflammatory Agents Non-Steroidalmedicine.diseaseIn vitroHemolysischemistryMechanics of MaterialsSelf-healing hydrogelsCeramics and CompositesTolmetinmedicine.drugBiomaterials
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Benzodiazepines: specific competitors for the binding of L-tryptophan to human serum albumin.

1975

By means of the gel filtration technique, the effect of nine benzo-diazepine derivates on the binding of l-tryptophan to human serum albumin was investigated. Using equimolar tryptophan and benzodiazepine concentrations, all benzodiazepines with binding constants higher than 104 (M−1), displace l-tryptophan from its binding site to a high degree. The mechanism of the displacement was characterized as a competition for a common binding site. Some of the benzodiazepines displace l-tryptophan to a greater extent than salicylic acid. The benzodiazepines and tryptophan are the only substances known with a high degree of stereospecific binding to human serum albumin. This study shows that there i…

medicine.drug_classSerum albuminPlasma protein bindingBinding CompetitiveBenzodiazepinesStructure-Activity RelationshipmedicineStructure–activity relationshipAnimalsHumansBinding siteSerum AlbuminPharmacologyBenzodiazepineBinding SitesbiologyChemistryTryptophanTryptophanSerum Albumin BovineGeneral MedicineMetabolismHuman serum albuminSalicylatesBiochemistrybiology.proteinChromatography Gelmedicine.drugProtein BindingNaunyn-Schmiedeberg's archives of pharmacology
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