Search results for "Gels"

New composite materials made up of nanofibers and hydrogel as biomimetic scaffolds for human pluripotent stem cell culture

2014

In Vitro Evaluation of Poly(lactide-co-glycolide) In Situ Forming Gels for Bedaquiline Fumarate Salt and Pharmacokinetics Following Subcutaneous Inje…

2021

This study evaluated in vitro and in vivo drug release of bedaquiline from in situ forming gels (ISGs) containing 200 mg eq./g bedaquiline fumarate salt prepared with four different grades of poly(d,l-lactide) (PDLLA) or poly(d,l-lactide-co-glycolide) (PLGA) with a lactide/glycolide ratio of 50/50 or 75/25 and acid (A) or ester (E) end-capping in N-methyl-2-pyrrolidone at a polymer/solvent ratio of 20/80% (w/w). Mean in vitro drug release in 0.05 M phosphate buffer pH 7.4 with 1% (w/v) sodium lauryl sulphate was 37.3, 47.1, 53.3, and 62.3% within 28 days for ISGs containing PLGA5050A, PDLLA, PLGA7525A, and PLGA7525E, respectively. The data suggested that drug release was primarily controlle…

Comparison of Post-Weld Treatment of High-Strength Steel Welded Joints in Medium Cycle Fatigue

2010

This paper presents a comparison of three post-weld treatments for fatigue life improvement of welded joints. The objective is to determine the most suitable post-weld treatment for implementation in mass production of certain crane components manufactured from very high-strength steel. The processes investigated are: burr grinding, TIG dressing and ultrasonic impact treatment. The focus of this investigation is on the so-called medium cycle area, i.e. 10 000-500 000 cycles and very high stress ranges. In this area of fatigue design, the use of very high strength steel becomes necessary, since the stress range can exceed the yield-strength of ordinary structural steel, especially when consi…

Lexical inferencing in reading in English on the secondary level

1998

"I wake up fabulous alltid" : en kvalitativ undersökning om kodväxlingens funktioner i ett finlandssvenskt radioprogram

2016

Tämän laadullisen tutkielman tarkoituksena oli tutkia ruotsin ja englannin välisen koodinvaihdon funktioita suomenruotsalaisessa nuorille suunnatussa radio-ohjelmassa. Tutkielman tavoitteena oli vastata seuraavaan tutkimuskysymykseen: mitä kommunikatiivisia funktioita ruotsin ja englannin välisellä koodinvaihdolla on suomenruotsalaisessa Succémorgon-radio-ohjelmassa? Tutkimusmateriaali koostui tutkittavana olleen radio-ohjelman viidestä satunnaisesti valitusta podcast-jaksosta huhtikuun ja elokuun väliseltä ajalta vuodelta 2015. Tutkielmassa sovellettiin keskusteluntutkimuksellisia menetelmiä karkean litteroinnin muodossa. Tutkimusaineiston analyysin pohjalta tutkielmassa identifioitiin sei…

IAEA Contribution to Nanosized Targeted Radiopharmaceuticals for Drug Delivery.

2022

The rapidly growing interest in the application of nanoscience in the future design of radiopharmaceuticals and the development of nanosized radiopharmaceuticals in the late 2000′s, resulted in the creation of a Coordinated Research Project (CRP) by the International Atomic Energy Agency (IAEA) in 2014. This CRP entitled ‘Nanosized delivery systems for radiopharmaceuticals’ involved a team of expert scientist from various member states. This team of scientists worked on a number of cutting-edge areas of nanoscience with a focus on developing well-defined, highly effective and site-specific delivery systems of radiopharmaceuticals. Specifically, focus areas of various teams of scientists com…

Le potenzialità delle colture in vitro nella conservazione e diffusione di germoplasma di Morus spp.

2009

Solid state NMR studies of gels derived from low molecular mass gelators

2016

Steroidal supramolecular metallogels

2020

The review deals with an expanding number of steroidal compounds that are capable of forming a metallogel providing a multitude of novel materials rich in their properties. The future of steroidal metallogels holds a myriad of potential applications as new intelligent materials. Detection of potentially harmful compounds without expensive instrumentation, entrapment of environmentally hazardous substances, and sensitive and selective nanomaterials represent only a few of these potential applications. This article reviews the design, synthesis, characterization, and applications of steroidal metallogels. peerReviewed

On the mechanism of radiation synthesis of nanogels

2016

Radiation-engineered poly(N-vinyl pyrrolidone) nanogels are very interesting biocompatible nanocarriers for i.v. administration of therapeutics and contrast agents for bioimaging among other applications. Nanogels are usually produced upon irradiation of dilute aqueous polymer solutions. Under these conditions, the polymer radicals formed primarily react via intramolecular radical-radical combination forming intramolecular crosslinks. The manufacturing process is fast and effective and grants excellent control of particle size and simultaneous sterilization of the formed nanogels. Interestingly, primary amino groups and carboxyl groups, useful for (bio)conjugation, are also formed in a dose…