Search results for "Generation"
showing 10 items of 3050 documents
Persistence of Occupational Segregation: The Role of the Intergenerational Transmission of Preferences
2007
This article provides an explanation of the evolution and persistence of the women's segregation in jobs with less on-the-job training opportunities within the framework of an overlapping generations model with intergenerational transmission of preferences. ‘Job-priority’ and ‘family-priority’ preferences are considered. Firms’ policy and the distribution of women's preferences are endogenously and simultaneously determined in the long run. The results show though the gender gap in training will diminish, it will also persist over time. This is because both types of women's preferences coexist at the steady state due to the socialisation effort of parents to preserve their own cultural valu…
Innate immunity repairs gut lining
2015
It emerges that innate immune cells called group 3 innate lymphoid cells signal directly to intestinal stem cells to promote the replacement of damaged epithelial cells lining the gut. See Letter p.560 The cellular signals supporting normal epithelial intestine maintenance through regulation of intestinal stem cell (ISC) activity are well characterized, but the signals involved in the regulation of the ISC compartment after damage are still unclear. Alan Hanash and colleagues have found that innate lymphoid cells produce interleukin-22 (IL-22) after injury to increase the growth of mouse intestinal organoids. They further show that recombinant IL-22 promotes ISC expansion in both human and …
AnyDSL: a partial evaluation framework for programming high-performance libraries
2023
This paper advocates programming high-performance code using partial evaluation. We present a clean-slate programming system with a simple, annotation-based, online partial evaluator that operates on a CPS-style intermediate representation. Our system exposes code generation for accelerators (vectorization/parallelization for CPUs and GPUs) via compiler-known higher-order functions that can be subjected to partial evaluation. This way, generic implementations can be instantiated with target-specific code at compile time. In our experimental evaluation we present three extensive case studies from image processing, ray tracing, and genome sequence alignment. We demonstrate that using partial …
miRNAs and Genes Involved in the Interplay between Ocular Hypertension and Primary Open-Angle Glaucoma. Oxidative Stress, Inflammation, and Apoptosis…
2021
Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2077-0383/10/11/2227 En esta investigación también participan: Mar Valero Vello, Silvia M. Sanz González, José E. O'Connor, David Galarreta Mira, María D. Pinazo-Durán y Vicente Zanón Moreno. Este artículo pertenece al número especial "Recent Clinical Research on Glaucoma". Glaucoma has no cure and is a sight-threatening neurodegenerative disease affecting more than 100 million people worldwide, with primary open angle glaucoma (POAG) being the most globally prevalent glaucoma clinical type. Regulation of gene expression and gene networks, and its multifactorial pathways involved in glaucoma disease are landmark…
Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool.
2015
Tissue homeostasis is achieved through a balance of cell production (growth) and elimination (regression). In contrast to tissue growth, the cells and molecular signals required for tissue regression remain unknown. To investigate physiological tissue regression, we use the mouse hair follicle, which cycles stereotypically between phases of growth and regression while maintaining a pool of stem cells to perpetuate tissue regeneration. Here we show by intravital microscopy in live mice that the regression phase eliminates the majority of the epithelial cells by two distinct mechanisms: terminal differentiation of suprabasal cells and a spatial gradient of apoptosis of basal cells. Furthermor…
PERSEUS-IT 24-month analysis: a prospective observational study to assess the effectiveness of intravitreal aflibercept in routine clinical practice …
2022
Abstract Purpose PERSEUS-IT (NCT02289924) was a prospective, observational, 2-year study evaluating the effectiveness and treatment patterns of intravitreal aflibercept (IVT-AFL) in patients with neovascular age-related macular degeneration (nAMD) in routine clinical practice in Italy. Methods Treatment-naïve patients with nAMD receiving IVT-AFL per routine clinical practice were enrolled. The primary endpoint was mean change in visual acuity (VA; decimals) from baseline to month (M) 12 and M24. Outcomes were evaluated for the overall study population and independently for the 2 treatment cohorts: regular (3 initial monthly doses, ≥ 7 injections by M12, and ≥ 4 injections between M12 and M2…
Demo - A Cell-level Traffic Generator for LoRa Networks
2017
In this demo we present and validate a LoRa cell traffic generator, able to emulate the behavior of thousands of low-rate sensor nodes deployed in the same cell, by using a single Software Defined Radio (SDR) platform. Differently from traditional generators, whose goal is creating packet flows which emulate specific applications and protocols, our focus is generating a combined radio signal, as seen by a gateway, given by the super-position of the signals transmitted by multiple sensors simultaneously active on the same channel. We argue that such a generator can be of interest for testing different network planning solutions for LoRa networks.
Laser Assisted Atomic Ionization by a Short XUV Pulse
2015
We report on numerical results of energy spectra of photoelectrons emitted by irradiating an hydrogen atom with a relatively weak single attosecond XUV pulse in the presence of a two-color IR laser pulse. The densities of probabilities have been obtained by treating the interaction of the atom with the XUV radiation at the first order of the time-dependent perturbation theory and describing the emitted electron through the Coulomb-Volkov wavefunction. The results of the calculations agree with the ones found by numerically solving the time-dependent Schrödinger equation. Specifically, we use an algorithm that implements an high recision variant of the Cranck Nicolson integration method and …