Search results for "Generation"
showing 10 items of 3050 documents
Novel second-order nonlinear optical polymer materials containing indandione derivativatives as a chromophore
2006
Second order non linear optical (NLO) properties of sPMMA based host-guest systems containing eight dimethylaminobenzylidene -1, 3 - indandione (DMABI) related chromophores have been investigated by means of quantum chemical calculations and SHG experimental characterization. Ab initio calculations with basis set 6-31G were used for molecular geometry determination as well as in the calculations of molecular hyperpolarizability by FF approach. Influence of the chromophore concentration on the host-guest film NLO performance was obtained by SHG Maker fringe experiments. The highest value of d53233 =80 pm/V (frequency corrected value d033 =12 pm/V) at chromophore concentration 15 %wt have bee…
Trends in Patient Generated Data – An Initial Review
2019
In recent years, patient-centered care has gained significant momentum in healthcare and the patient is more involved as an active participant in data generation. In this state of the art review we ...
Description of Dryocosmus destefanii new species (Hymenoptera: Cynipidae: Cynipini) from Quercus suber L. in Italy
2018
A new species, Dryocosmus destefanii Cerasa & Melika n. sp. associated with a Cerris section oak, Quercus suber L., is described from Italy. Description, diagnosis, host associations and biology for the new species and an illustrated identification key to the Western Palaearctic Dryocosmus species are given. The description is supported by morphological and molecular data.
Glial Promoter Selectivity following AAV-Delivery to the Immature Brain
2013
Recombinant adeno-associated virus (AAV) vectors are versatile tools for gene transfer to the central nervous system (CNS) and proof-of-concept studies in adult rodents have shown that the use of cell type-specific promoters is sufficient to target AAV-mediated transgene expression to glia. However, neurological disorders caused by glial pathology usually have an early onset. Therefore, modelling and treatment of these conditions require expanding the concept of targeted glial transgene expression by promoter selectivity for gene delivery to the immature CNS. Here, we have investigated the AAV-mediated green fluorescent protein (GFP) expression driven by the myelin basic protein (MBP) or gl…
Second harmonic generation and beam cleaning in optically poled multimode graded-index fibers
2017
Recent experimental results have confirmed that nonlinear effects in multimode graded-index (MM-GRIN) fibers lead to a wealth of observable spatiotemporal effects. In spite of the large number of modes supported by the fiber, by increasing the input power the transverse profile evolves in a clean bell-shaped beam [1, 2]. Next, the input laser line experiences a strong spectral broadening and Geometric Parametric Instability (GPl) peaks are observed [3].
Spatial beam cleaning in quadratic nonlinear medium
2018
We show experimentally that a laser beam scrambled by propagation in a short segment of multimode fiber may be cleaned by the nonlinear propagation in KTP cristal with type-II second-harmonic generation.
Antoni de Martí i Franquès i la generació espontània: Els conflictes entre ciència i religió en el treball del naturalista
2014
Antoni de Marti i Franques, el naturalista tarragoni que va viure en la segona part del segle XVIII i primers decennis del XIX, conegut especialment pels seus notables experiments dedicats a l’estudi de la composicio de l’aire atmosferic, dedica bona part del seu treball experimental a estudiar la generacio espontania. A traves dels manuscrits de Marti i Franques que es conserven i pel testimoni dels seus contemporanis, sabem que estava convencut d’haver comprovat experimentalment l’existencia d’aquest fenomen. Pero, com que era un fervent catolic, no va voler publicar res sobre aquest tema en vida per temor de ser acusat d’heretge. Tampoc el seus descendents van publicar res de la seva obr…
Experimental and theoretical evidence for bilayer-by-bilayer surface melting of crystalline ice
2017
On the surface of water ice, a quasi-liquid layer (QLL) has been extensively reported at temperatures below its bulk melting point at 273 K. Approaching the bulk melting temperature from below, the thickness of the QLL is known to increase. To elucidate the precise temperature variation of the QLL, and its nature, we investigate the surface melting of hexagonal ice by combining noncontact, surface-specific vibrational sum frequency generation (SFG) spectroscopy and spectra calculated from molecular dynamics simulations. Using SFG, we probe the outermost water layers of distinct single crystalline ice faces at different temperatures. For the basal face, a stepwise, sudden weakening of the hy…
ADDISC lumbar disc prosthesis: Analytical and FEA testing of novel implants
2023
The intact intervertebral disc is a six-freedom degree elastic deformation structure with shock absorption. 'Ball-and-socket' TDR do not reproduce these properties inducing zygapophyseal joint overload. Elastomeric TDRs reproduce better normal disc kinematics, but repeated core deformation causes its degeneration. We aimed to create a new TDR (ADDISC) reproducing healthy disc features. We designed TDR, analyzed (Finite Element Analysis), and measured every 500,000 cycles for 10 million cycles of the flexion-extension, lateral bending, and axial rotation cyclic compression bench-testing. In the inlay case, we weighted it and measured its deformation. ADDISC has two semi-spherical articular s…
Remyelinating strategies in multiple sclerosis.
2014
Multiple sclerosis (MS) is the most common chronic inflammatory demyelinating disorder of the CNS characterized by infiltration of immune cells and progressive damage to myelin sheaths and neurons. In recent years, the importance of the neuronal compartment in the early pathology of multiple sclerosis has become increasingly clear. Direct axonal damage within the early stages of inflammation as well as neuronal injury as a result of chronic demyelination are essential factors for the development of long-term disability in patients. Viewing MS as both inflammatory and neurodegenerative has significant implications for treatment, with remyelination of denuded axons to protect neurons from dam…