Search results for "Generation"
showing 10 items of 3050 documents
La transmissió lingüística intergeneracional a Castelló de la Plana i la Franja: La rellevància dels usos entre progenitors
2020
Fa 50 anys, a Conflicte lingüístic valencià, Rafael L. Ninyoles situava el trencament de la transmissió familiar del català com a resultat i manifestació externa de conflictes socials i de classes, especialment visibles enmig del procés de modernització econòmica i mobilitat social accelerada del País Valencià dels anys 60 del segle XX. En aquest article partim de dos estudis de cas quantitatius sobre la transmissió intergeneracional de les llengües a Castelló de la Plana i les comarques centrals de la Franja per a actualitzar el seu diagnòstic i matisar la visió d'aquest fenomen com a resultat de decisions dels progenitors imposades verticalment a la descendència. Hi proposem que els usos …
Tuning the high-order harmonic lines of a Nd:Glass laser for soft x-ray laser seeding
2010
Taking advantage of the non-adiabatic blue-shift of high-order harmonics generated by a fixed frequency Nd:Glass laser system, we are able to report more than 50 % coverage of the XUV spectral range between 18 nm and 35 nm. The generated harmonic lines are capable of seeding Ni-like Y, Zr and Mo soft x-ray lasers and others.
Stable and long-time operation of a soft x-ray laser for user applications experiments
2011
LASERIX is a high-power laser facility leading to High-repetition-rate XUV laser pumped by Titanium:Sapphire laser. The aim of this laser facility is to offer Soft XRLs in the 30-7 nm range and auxiliary IR beam that could also be used to produce synchronized XUV sources. This experimental configuration highly enhances the scientific opportunities of the facility, giving thus the opportunity to realize both X-ray laser experiments and more generally pump/probe experiments, mixing IR and XUV sources. In this contribution, the main results concerning both the development of XUV sources(X-Ray lasers and HHG sources) and their use for applications are presented.
Hydrophobic Encapsulated Phosphonium Salts-Synthesis of Weakly Coordinating Cations and their Application in Wittig Reactions
2015
Large and rigid tetraarylphosphonium tetrafluoroborate salts have been synthesized representing weakly coordinating cations with diameters of several nanometers. Divergent dendritic growth by means of thermal Diels-Alder cycloaddition was employed for the construction of the hydrophobic polyphenylene framework up to the third generation. X-ray crystal structure analysis of first-generation phosphonium tetrafluoroborate supported the rigidity of the non-collapsible shell around the phosphorus center and gave insight into solid-state packing and cation-anion distances. Copper(I)-catalyzed azide-alkyne ligation served as reliable method for the preparation of a first-generation triazolylphenyl…
URBAN REGENERATION AND BUILT HERITAGE
2021
The rehabilitation project is mainly addressed to the adaptation of new housing and urban needs, but it is obviously conditioned and/or “constrained” by the limitation of the building itself, in particular when its intrinsic characteristics must be preserved. In this paper we focus on some aspects of the general framework of urban regeneration: the balance on the “urban question” and on the methodology of integrated planning; the connection between quality and urban liveability; the sharing of the objectives of regeneration and its meanings. Without claiming to be exhaustive, some of the “enabling” conditions and the “indispensable” reasons and conditions for guiding the process of urban re…
Macrophage migration inhibitory factor is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety,…
2011
Intensive research is devoted to unravel the neurobiological mechanisms mediating adult hippocampal neurogenesis, its regulation by antidepressants, and its behavioral consequences. Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine that is expressed in the CNS, where its function is unknown. Here, we show, for the first time, the relevance of MIF expression for adult hippocampal neurogenesis. We identify MIF expression in neurogenic cells (in stem cells, cells undergoing proliferation, and in newly proliferated cells undergoing maturation) in the subgranular zone of the rodent dentate gyrus. A causal function for MIF in cell proliferation was shown using genetic (M…
SECOND-GENERATION MIGRANTS: IDENTIFICATION PROBLEMS
2022
The expression “second-generation” is particularly complex for several reasons. First of all, because of the link with the term “generation,” the use of the adjective “second,” and the meanings attributed to it by those so defined. Moreover, the conceptual category refers to different situations, each with different issues that are difficult to compare. The condition of the second generation or of the set of second-generation migrants appears ambiguous because it oscillates between forms of alienation and forms of belonging, between situations of marginality and situations of activism and protagonism. Therefore, the expression “second-generation” often appears reductive for a number of reas…
Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium.
2019
Purpose: To evaluate the roles of known myopia-associated genetic variants for development of myopic macular degeneration (MMD) in individuals with high myopia (HM), using case-control studies from the Consortium of Refractive Error and Myopia (CREAM). Methods: A candidate gene approach tested 50 myopia-associated loci for association with HM and MMD, using meta-analyses of case-control studies comprising subjects of European and Asian ancestry aged 30 to 80 years from 10 studies. Fifty loci with the strongest associations with myopia were chosen from a previous published GWAS study. Highly myopic (spherical equivalent [SE] ≤ -5.0 diopters [D]) cases with MMD (N = 348), and two sets of cont…
Modelling the regenerative niche: a major challenge in biomaterials research
2015
By definition, biomaterials are developed for clinical application. In the field of regenerative medicine their principal function is to play a significant, and, if possible, an instructive role in tissue healing. In the last analysis the latter involves targeting the 'regenerative niche'. The present paper will address the problem of simulating this niche in the laboratory and adopts a life science approach involving the harnessing of heterotypic cellular communication to achieve this, that is, the ability of cells of different types to mutually influence cellular functions. Thus, co-culture systems using human cells are the methodological focus and will concern four exemplary fields of re…
In vitro Shoot Regeneration from Flower and Leaf Explants in Rhododendron
2003
Rhododendron shoot regeneration was accomplished using either flower explants (each consisting of ovary with pedicel) of Rhododendron cvs. Nova Zembla and Irina or leaves isolated from in vitro grown Rhododendron catawbiense Michx. Multiple shoot tip clumps were obtained on Anderson's medium containing 0.5 to 1.5 mg dm−3 thidiazuron (TDZ) in combination with 12 to 15 mg dm−3 N6-[2-isopentenyl]adenine (2iP) and 1 to 3 mg dm−3 indole-3-butyric acid (IBA). After 16 weeks on the regeneration media, explants with shoot tip clumps were transferred for shoot elongation to Anderson's medium with 3 mg dm−3 2iP. Two months later, the shoots have reached 5 to 40 mm in length and were fit for subcultiv…