Search results for "Generation"
showing 10 items of 3050 documents
From Myth to Science. A Short Survey on Heredity and Its Causes in Ancient Greece
2017
In this contribution, I deal with the notion of “cause” concerning hereditary diseases in ancient Greece. A notion of hereditary disease is already foreshadowed in myths, where guilt is often depicted as a pathologic contamination (miasma) affecting both the individual and his offspring (ghenos). The notion of miasma especially concerns diseases whose signs are not visible: in such cases, either gods or maleficent daemons were believed to harass human beings and inflict them punishments that took the shape of diseases. Contamination mainly spreads itself by means of blood-shedding: the slaughter of kinsmen (especially the murder of one’s parents) was widely considered as a main cause of man…
Recent Progress in the WCLL Breeding Blanket Design for the DEMO Fusion Reactor
2018
The water-cooled lithium-lead (PbLi) breeding blanket is one of the candidate systems considered for the implementation in the European Demonstration Power Plant (DEMO) nuclear fusion reactor. This concept employs PbLi liquid metal as tritium breeder and neutron multiplier, water pressurized at 15.5 MPa as the coolant, and EUROFER as the structural material. The current design is based on the single module segment approach and follows the requirements of the DEMO-2015 baseline design. The module is constituted by a basic toroidal-radial cell that is recursively repeated along the poloidal direction where the liquid metal flows along a radial-poloidal path. The heat generated by the fusion r…
Territori marginali e finestre di opportunità. Norcia tra gli eventi sismici del 1979 e del 2016
2021
Il contributo intende indagare la stretta connessione tra disastri naturali e traiettorie di sviluppo territoriale e come queste ultime siano determinate in larga parte dalle politiche pubbliche messe in atto nella fase post-emergenziale. A seguito dei disastri, il dibattito pubblico e politico, i grandi investimenti, la possibilità di operare trasformazioni urbanistiche possono generare uno scenario di opportunità e rinascita definibile come «window of opportunity». Si prende qui in considerazione l’evento sismico del 1979 di Norcia, insieme al relativo processo di ricostruzione, avviato assieme a un piano di rinascita economica incentrato sulle vocazioni locali e capace di frenare le tend…
Development of ultrasound-assisted digestion methods for the determination of toxic element concentrations in ash samples by ICP-OES
2011
The present thesis introduces several ultrasound-assisted digestion methods developed for the determination of toxic element concentrations in ash samples by inductively coupled plasma optical emission spectrometry (ICP-OES). Ultrasound-assisted digestion is a quite new technique used for sample pre-treatment purposes, especially in difficult sample matrixes. Elements determined are As, Ba, Co, Cr, Cu, Ni, Pb, Sb, Sr, V, and Zn. Most of the elements determined exist at a trace or ultra trace level in ashes and most are potential risks in the environment or human body even at low concentrations. Most of the selected elements can be determined directly by ICP-OES, but for the determination of…
Autophagy
2021
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide…
Collective Locomotion of Human Cells, Wound Healing and Their Control by Extracts and Isolated Compounds from Marine Invertebrates
2020
The collective migration of cells is a complex integrated process that represents a common theme joining morphogenesis, tissue regeneration, and tumor biology. It is known that a remarkable amount of secondary metabolites produced by aquatic invertebrates displays active pharmacological properties against a variety of diseases. The aim of this review is to pick up selected studies that report the extraction and identification of crude extracts or isolated compounds that exert a modulatory effect on collective cell locomotion and/or skin tissue reconstitution and recapitulate the molecular, biochemical, and/or physiological aspects, where available, which are associated to the substances und…
MATERNAL EXPOSURE TO STRESSFUL/TRAUMATIC EVENTS AND AUTISM SPECTRUM DISORDERS IN OFFSPRING: PRELIMINARY FINDINGS OF A CASE CONTROL PILOT STUDY.
2023
The correlation between maternal exposure to stressful and traumatic events during pregnancy and autism spectrum disorder (ASD) in offspring has been studied in the literature. Fewer studies, however, have considered the mother's exposure to traumatic events during childhood. This work focuses on maternal exposure to these events in childhood and/or adulthood, relating it to autism spectrum disorder in offspring. A questionnaire was used to assess whether and to what type of event the mothers have been exposed, and to assess eventual peri-traumatic dissociation related to the traumatic event. The mothers involved in this study were recruited at the Child Neuropsychiatry Outpatient Clinic of…
Enseñar E/LE a la primera generación de nativos digitales
2017
Resumen: Este artículo trata de la primera generación de verdaderos nativos digitales en Europa, nacidos en torno al año 2000 y que en la actualidad asisten a los institutos de secundaria. Son diferentes a los de generaciones anteriores debido sobre todo al impacto que la tecnología ha tenido en sus vidas, pero la mayoría sigue sistemas educativos desfasados, diseñados para alumnos del siglo pasado. Muchos profesores intentan adaptarse a la nueva situación incorporando las TIC en sus cursos. La autora analiza el proceso de creación de un telediario, actividad realizada en el marco de un proyecto piloto de uso de los Ipad en los cursos de E/LE. Este proyecto obtuvo el Primer Premio del concu…
A Critical Review of Alien Limb-Related Phenomena and Implications for Functional Magnetic Resonance Imaging Studies
2021
Consensus criteria on corticobasal degeneration (CBD) include alien limb (AL) phenomena. However, the gist of the behavioral features of AL is still “a matter of debate.” CBD-related AL has so far included the description of involuntary movements, frontal release phenomena (frontal AL), or asomatognosia (posterior or “real” AL). In this context, the most frequent symptoms are language and praxis deficits and cortical sensory misperception. However, asomatognosia requires, by definition, intact perception and cognition. Thus, to make a proper diagnosis of AL in the context of CBD, cognitive and language dysfunctions must be carefully verified and objectively assessed. We reviewed the current…
La relación entre abuelos y nietos. Factores que predicen la calidad de la relación intergeneracional
2004
This study tries to identify the main factors determining the quality in grandparent/ grandchild relationships from the perspective of grandchildren. Three hundred and sixty one Spanish young adults responded to questions concerning the quality of their relationship with the "preferred" or "most close" grandparent. Results indicated the following aspects as significant predictors of grandparent-grandchild relationship: a) the frequency of contact between grandparents-grandchildren; b) the quality of the parent-grandparent relationship; c) the number of shared activities; and d) the perception of the grandparent as "caregiver" and "teacher".<br><br>El presente estudio se centra e…