Search results for "Genes."

showing 10 items of 13909 documents

Comparative histological and immunohistochemical study of ameloblastomas and ameloblastic carcinomas

2017

Background This study aimed to compare the histological and immunohistochemical characteristics of ameloblastomas (AM) and ameloblastic carcinomas (AC). Material and Methods Fifteen cases of AM and 9 AC were submitted to hematoxilin and eosin (H&E) and immunohistochemical analysis with the following antibodies: cytokeratins 5,7,8,14 and 19, Ki-67, p53, p63 and the cellular adhesion molecules CD138 (Syndecan-1), E-cadherin and β-catenin. The mean score of the expression of Ki-67 and p53 labelling index (LIs) were compared between the groups using the t test. A value of p<0.05 was considered to be statistically significant. Results All cases were positive for CKs 5, 14 and 19, but negative fo…

tumorsMalePathologyAntibodies Neoplasmameloblastic carcinomaMalignant transformation0302 clinical medicineAmeloblastomaChildp63biologyki-67Middle Aged:CIENCIAS MÉDICAS [UNESCO]ImmunohistochemistryJaw Neoplasms030220 oncology & carcinogenesisKi-67immunohistochemistryUNESCO::CIENCIAS MÉDICASImmunohistochemistry//purl.org/pe-repo/ocde/ford#3.02.11 [https]Femalesyndecan-1 cd138Adultmedicine.medical_specialtyAdolescentgovernment.form_of_governmentcateninMalignancyAmeloblastoma03 medical and health sciencesYoung AdultDentistry Oral Surgery & MedicineexpressionmedicineHumansgeneGeneral DentistryOral Medicine and PathologyCadherinResearchcytokeratinsodontogenic030206 dentistrymedicine.disease//purl.org/pe-repo/ocde/ford#3.02.14 [https]Ameloblastic carcinomaOtorhinolaryngologyCateningovernmentbiology.proteinSurgeryodontogenic-tumorse-cadherin
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Work Stressors and Intention to Leave the Current Workplace and Profession: The Mediating Role of Negative Affect at Work.

2022

The first aim of this study was to determine whether organisational constraints, interpersonal conflicts at work, workload and negative affect at work have a positive relationship with intention to leave a current job or profession. The second aim was to investigate whether negative affect at work mediates the relationship between work stressors and intention to leave a current job or profession. The study was a quantitative cross-sectional design in nature. Data were collected between March and April 2022. The sample consisted of 306 midwives working in the Polish public health service. The theoretical model was tested using structural equation modelling. The results confirmed positive dir…

turnover intentionHealth Toxicology and Mutagenesiswork-related stress; turnover intention; affect at work; stressor-emotion theory; midwivesPublic Health Environmental and Occupational HealthPersonnel Turnoverstressor-emotion theoryIntentionJob SatisfactionmidwivesCross-Sectional StudiesSurveys and Questionnaireswork-related stressaffect at workWorkplaceInternational journal of environmental research and public health
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Using Heart Rate Variability Methods for Health-Related Outcomes in Outdoor Contexts : A Scoping Review of Empirical Studies

2023

Heart rate variability (HRV) is a psychophysiological variable that is often used in applied analysis techniques to indicate health status because it provides a window into the intrinsic regulation of the autonomic nervous system. However, HRV data analysis methods are varied and complex, which has led to different approaches to data collection, analysis, and interpretation of results. Our scoping review aimed to explore the diverse use of HRV methods in studies designed to assess health outcomes in outdoor free-living contexts. Four database indexes were searched, which resulted in the identification of 17,505 candidate studies. There were 34 studies and eight systematic reviews that met t…

ulkoilusykevälivaihtelusykeHealth Toxicology and MutagenesiswildernesshyvinvointiPublic Health Environmental and Occupational HealthnaturehealthHeart Rate Variability (HRV)luontoAutonomic Nervous System (ANS)wellnesskatsauksetoutdoorswell-beingautonominen hermostoterveysvaikutuksetRR Intervalscoping reviewterveys
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Experimental Constraints on the Deep Magma Feeding System at StromboliVolcano, Italy

2009

International audience; New experiments have been performed on a high-K basalt (PST-9) from Stromboli volcano, Italy, to constrain the physical conditions of golden pumice magmas at their storage level and discuss their petrogenesis. Fluid-present, H2O- and CO2-bearing, near-liquidus experiments were performed at 11508C between 100 and 400MPa and under oxidizing conditions. Glasses were analyzed by Fourier transform IR spectroscopy and their H2O and CO2 concentrations compared with those in glass inclusions.Most glass inclusions cluster near the 200MPa isobar, suggesting entrapment at a depth of ~8 km. Golden pumice magmas have viscosities of 7.9 Pa s and densities of 2.48-2.57 g/cm3. Compo…

ultra-calcic melts010504 meteorology & atmospheric sciences[SDE.MCG]Environmental Sciences/Global ChangesMineralogyLiquidus010502 geochemistry & geophysics01 natural sciencesphysical propertiesGeochemistry and PetrologyPumiceexperimental petrology[SDU.STU.VO]Sciences of the Universe [physics]/Earth Sciences/VolcanologyStromboli0105 earth and related environmental sciencesMelt inclusionsPetrogenesisBasaltgeographygeography.geographical_feature_categorygolden pumiceSettore GEO/07 - Petrologia E PetrografiaGeophysicsVolcano13. Climate actionMagmaexperimental petrology Stromboli yellow pumicePrimitive mantlemagma storageGeology
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Experimental Evolution Reveals a Genetic Basis for Membrane-Associated Virus Release

2021

Many animal viruses replicate and are released from cells in close association to membranes. However, whether this is a passive process or is controlled by the virus remains poorly understood. Importantly, the genetic basis and evolvability of membrane-associated viral shedding have not been investigated. To address this, we performed a directed evolution experiment using coxsackievirus B3, a model enterovirus, in which we repeatedly selected the free-virion or the fast-sedimenting membrane-associated viral subpopulations. The virus responded to this selection regime by reproducibly fixing a series of mutations that altered the extent of membrane-associated viral shedding, as revealed by fu…

ultra-deep sequencingUltra-deep sequencingvirusesMutagenesis (molecular biology technique)Viral transmissionBiologyAcademicSubjects/SCI01180Virus03 medical and health sciencesGeneticsViral sheddingdirected evolutionMolecular BiologyEcology Evolution Behavior and SystematicsDiscoveriesEnterovirus030304 developmental biology0303 health sciencesExperimental evolution030306 microbiologyenterovirusviral transmissionAcademicSubjects/SCI01130Directed evolutionVirologyvirus–membrane interactionsBiological EvolutionVirus ReleaseVirus–membrane interactions3. Good healthEnterovirus B HumanVirus SheddingEvolvabilityCapsidAmino Acid SubstitutionDirected evolutionCapsid ProteinsGenetic FitnessMolecular Biology and Evolution
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2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation

2020

2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation

unstable anginaMyocardial ischaemia[SDV]Life Sciences [q-bio]Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]dual antithrombotic therapyGuidelineheparin030204 cardiovascular system & hematologyPlatelet inhibitionantiplatelet0302 clinical medicineST segmentMedicinedabigatranMyocardial infarctionguidelinesglycoprotein iib/iiia inhibitorsanticoagulationNon-ST Elevated Myocardial InfarctionrivaroxabanComputingMilieux_MISCELLANEOUSreproductive and urinary physiologydiabetesbleedingsbivalirudinatherothrombosiDisease ManagementangioplastyGuidelines • acute cardiac care • acute coronary syndrome • angioplasty • anticoagulation • antiplatelet • apixaban • aspirin • atherothrombosis • betablockers • bleedings • bivalirudin • bypass surgery • cangrelor • chest pain unit • clopidogrel • dabigatran • diabetes • dual antithrombotic therapy • early invasive strategy • edoxaban • enoxaparin • European Society of Cardiology • fondaparinux • glycoprotein IIb/ IIIa inhibitors • heparin • high-sensitivity troponin • minoca • myocardial ischaemia • myocardial infarction • nitrates • non-ST-elevation myocardial infarction • platelet inhibition • prasugrel • recommendations • revascularization • rhythm monitoring • rivaroxaban • stent • ticagrelor • triple therapy • unstable anginaenoxaparinGeneral MedicineClopidogrel3. Good healthearly invasive strategymyocardial infarctiontriple therapy030220 oncology & carcinogenesisHigh sensitivity troponinembryonic structuresCardiologyPlatelet aggregation inhibitorrevascularizationbiological phenomena cell phenomena and immunityCardiology and Cardiovascular MedicineTicagrelormedicine.drugHumanrecommendationAcute coronary syndromemedicine.medical_specialtyaspiringlycoprotein IIb/IIIa inhibitornon-ST-elevation myocardial infarctionapixabanrhythm monitoringEuropean Society of Cardiologyticagrelor03 medical and health sciencesnitrateatherothrombosisbetablockersInternal medicineacute cardiac careminocachest pain unitDiseases of the circulatory (Cardiovascular) systemHumansIn patientAcute Coronary SyndromeclopidogrelUnstable anginaurogenital systemnitratesbusiness.industryfondaparinuxbetablockerArrhythmias Cardiac030229 sport sciencesbleedingmedicine.diseasemyocardial ischaemiaplatelet inhibitionprasugreldiabeteGlycoprotein IIb/IIIa inhibitorsRC666-701bypass surgerySettore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARErecommendationsedoxabanhigh-sensitivity troponinstentbusinessPlatelet Aggregation Inhibitorscangrelor
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The impact of urban transformations on the morphology of streets networks

2017

This research takes place in the field of quantitative analysis of historical streets networks.During the last decades, many studies have used network analysis or space syntax approachin a diachronic perspective, either to observe the interdependence between networkconfigurations and land-use, or to explore the link between network configurations and knownurban phenomena, such as densification, dispersal or expansion. These researches often focuson one single transformation rather than on the long time evolution of networks. In this work,we will explore the evolution of the street network of Paris, between 1300 and 1871, and linkthis evolution to all the transformations that occurred in the…

urban historygraph theory[SHS.GEO] Humanities and Social Sciences/GeographyNetwork Morphogenesis
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MR Imaging of Uterus Didelphys Transverse Vaginal Septum Causing Hematometrocolpos and Renal Agenesis

2002

The association of uterus didelphys and unilateral blind vagina with ipsilateral renal agenesis is an infrequent urogenital malformation distinguished by a lesion of the mesonephric duct. In most patients, symptoms are present at the beginning of the menstrual cycle because a transverse vaginal septum on one side obstructs the flow of menses, which consequently collect. Magnetic resonance imaging allows a precise delineation of this congenital abnormality, clearly demonstrating the transverse vaginal septum with hematometrocolpos and uterus didelphys. Extending the magnetic resonance study to the abdomen and employing coronal sections with a wide field of view is important to search for ass…

urogenital systemGenitourinary systembusiness.industrymedia_common.quotation_subjectObstetrics and GynecologyAnatomyBlind vaginamedicine.diseaseMr imagingUterus didelphysMesonephric ductLesionmedicineRadiology Nuclear Medicine and imagingUterus malformation MR imagingmedicine.symptombusinessRenal agenesisMenstrual cyclemedia_commonJournal of Women's Imaging
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A New Academic Quality at Work Tool (AQ@workT) to Assess the Quality of Life at Work in the Italian Academic Context

2022

Refereed/Peer-reviewed The present study provides evidence for a valid and reliable tool, the Academic Quality at Work Tool (AQ@workT), to investigate the quality of life at work in academics within the Italian university sector. The AQ@workT was developed by the QoL@Work research team, namely a group of expert academics in the field of work and organizational psychology affiliated with the Italian Association of Psychologists. The tool is grounded in the job demands-resources model and its psychometric properties were assessed in three studies comprising a wide sample of lecturers, researchers, and professors: a pilot study (N = 120), a calibration study (N = 1084), and a validation study …

validationHealth Toxicology and MutagenesisPublic Health Environmental and Occupational HealthReproducibility of ResultReproducibility of Resultsacademic teaching staff assessment tool job demands-resources model quality of life in academia validationPilot Projectsjob demands-resources model; quality of life in academia; validation; academic teaching staff;job demands-resources model quality of life in academia validation academic teaching staff assessment tooljob demands-resources model; quality of life in academia; validation; academic teaching staff; assessment tooljob demands-resources modelacademic teaching staff; assessment tool; job demands-resources model; quality of life in academia; validation; Humans; Italy; Pilot Projects; Reproducibility of Results; Surveys and Questionnaires; Quality of LifeItalyacademic teaching staffSurveys and Questionnairesquality of life in academiaQuality of LifeSurveys and QuestionnaireHumansPilot Projectassessment toolHumanInternational Journal of Environmental Research and Public Health
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Students’ Perceptions of Instructional Rubrics in Neurological Physical Therapy and Their Effects on Students’ Engagement and Course Satisfaction

2021

One of the main challenges faced by physical therapy (PT) students is to learn the practical skills involved in neurological physical therapy (PT). To help them to acquire these skills, a set of rubrics were designed for formative purposes. This paper presents the process followed in the creation of these rubrics and their application in the classroom, noting that students perceived them as valid, reliable, and highly useful for learning. The perception of the validity and usefulness of the rubrics has different closely related dimensions, showing homogeneous values across the students´ sociodemographic and educational variables, with the exception of dedication to studying, which showed a …

validitymedicine.medical_specialtyFisioteràpiaProcess (engineering)formative assessmentHealth Toxicology and Mutagenesismedia_common.quotation_subjecteducationPersonal SatisfactionCourse satisfactionArticleFormative assessmentperceptionsNeurologia03 medical and health sciences0302 clinical medicinePerceptionstudents’ engagementmedicineHumansphysical therapyStudentsstudents’ perceptionsSet (psychology)Physical Therapy Modalitiesusefulnessmedia_commonrubricscourse satisfaction05 social sciencesDirect effectsRPublic Health Environmental and Occupational HealthReproducibility of Results050301 educationRubricstudents&#8217HomogeneousPhysical therapyMedicinePerception-- FormacióPsychology0503 education030217 neurology & neurosurgeryengagementInternational Journal of Environmental Research and Public Health
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