Search results for "Genetic Structures"
showing 10 items of 2107 documents
Carbonic anhydrase inhibitor with topical NSAID therapy to manage cystoid macular edema in a case of gyrate atrophy
2017
Purpose Gyrate atrophy of the choroid and retina (GACR) is a rare chorioretinal dystrophy characterized by a deficiency of the enzyme ornithine aminotransferase, inherited in an autosomal recessive pattern. Case Report We report a case of a 17-year-old girl with GACR, for whom the level of serum ornithine had been reduced by an arginine-restricted diet. The patient was responsive to an association of topical nonsteroidal anti-inflammatory drugs (NSAIDs) and a carbonic anhydrase inhibitor (CAI) to reduce cystoid macular edema (CME). Conclusions The efficacy of topical NSAIDs and systemic CAI association indicates that the imbalance in the distribution of retinal pigment epithelium membrane-b…
Gingival recession associated with Orthodontic treatment and root coverage
2010
Many patients seek to pursue orthodontic treatment for esthetic improvement. These patients present with mal- alignment of the anterior teeth. There was strong correlation between the severity and extent of gingival recessions and past orthodontic treatment, it was suggested that orthodontic tooth movement may lead to gingival recession. The principal objective in the treatment of gingival recession is to cover the exposed root surfaces to improve es- thetics and to reduce hypersensitivity. Different soft tissue grafting procedures have been proposed in the treatment of gingival recessions. Free gingival grafts (FGG) are a reliable method for treatment of gingival recessions: An autograft i…
Association between maxillary and mandibular apical base lengths and severity of dental crowding or spacing in Class II malocclusion subjects: An
2018
Background Anterior crowding/ spacing are one of the major problems that inspire patients to undergo orthodontic treatment. Several factors associated with anterior crowding/ spacing includes arch width and length, mesio-distal tooth diameter and proportions. The aim of the present study was to evaluate the relationship of maxillary and mandibular base lengths to the amount of anterior dental crowding/ spacing in patients with complete class II malocclusions. Material and methods A retrospective study was done with 152 patients who were divided into four groups according to the severity of pre-treatment dental crowding/spacing present in the mandibular arch. Measurements were performed on t…
Intravitreal delivery of AAV-NDI1 provides functional benefit in a murine model of Leber hereditary optic neuropathy.
2012
Leber hereditary optic neuropathy (LHON) is a mitochondrially inherited form of visual dysfunction caused by mutations in several genes encoding subunits of the mitochondrial respiratory NADH-ubiquinone oxidoreductase complex (complex I). Development of gene therapies for LHON has been impeded by genetic heterogeneity and the need to deliver therapies to the mitochondria of retinal ganglion cells (RGCs), the cells primarily affected in LHON. The therapy under development entails intraocular injection of a nuclear yeast gene NADH-quinone oxidoreductase (NDI1) that encodes a single subunit complex I equivalent and as such is mutation independent. NDI1 is imported into mitochondria due to an e…
"Table 33" of "Comprehensive measurements of $t$-channel single top-quark production cross sections at $\sqrt{s} = 7$ TeV with the ATLAS detector"
2021
Statistical correlation matrices for the normalized differential cross section as a function of $p_{\mathrm{T}}(\bar t)$.
"Table 35" of "Comprehensive measurements of $t$-channel single top-quark production cross sections at $\sqrt{s} = 7$ TeV with the ATLAS detector"
2021
Statistical correlation matrices for the normalized differential cross section as a function of $|y(\bar t)|$.
"Table 137" of "Measurements of $t\bar{t}$ differential cross-sections of highly boosted top quarks decaying to all-hadronic final states in $pp$ col…
2019
$m^{t\bar{t}}$ covariance matrix for relative differential cross-section in parton level
"Table 136" of "Measurements of $t\bar{t}$ differential cross-sections of highly boosted top quarks decaying to all-hadronic final states in $pp$ col…
2019
$m^{t\bar{t}}$ correlation matrix for absolute differential cross-section in parton level
Neuropharmacology of vision in goldfish: A review
2009
AbstractThe goldfish is one of the few animals exceptionally well analyzed in behavioral experiments and also in electrophysiological and neuroanatomical investigations of the retina. To get insight into the functional organization of the retina we studied color vision, motion detection and temporal resolution before and after intra-ocular injection of neuropharmaca with known effects on retinal neurons. Bicuculline, strychnine, curare, atropine, and dopamine D1- and D2-receptor antagonists were used. The results reviewed here indicate separate and parallel processing of L-cone contribution to different visual functions, and the influence of several neurotransmitters (dopamine, acetylcholin…
Ahmed valve, suture-less implantation: A new approach to an easier technique.
2013
Purpose Tissue adhesives have been used in ophthalmology instead of sutures to minimize the operating time. This case series investigated the effectiveness and safety of use of cyanoacrylate in Ahmed valve implantation through pars plana for refractory glaucoma. Patients and methods Seventeen eyes of 17 patients with refractory glaucoma underwent Ahmed valve scleral suture-less implantation through pars plana with a cyanoacrylate suture of the plate. Refractory glaucoma was defined as intraocular pressure (IOP) ≥ 21 mm Hg with antiglaucoma eye drops, good adherence to treatment, and no previous glaucoma surgery. IOP control and development of complications were evaluated during the follow-u…