Search results for "Genetic Structures"
showing 10 items of 2107 documents
Clinical Features and Natural History of AMD on OCT
2009
Despite recent progress, age-related macular degeneration (AMD) remains the leading cause of vision loss in high-income countries, and its incidence appears to be increasing, probably due to longer life span and improved methods of detection.
Optical Coherence Tomography in Glaucoma
2012
Retinal nerve fiber layer (RNFL) thinning and optic nerve head cupping are key diagnostic features of glaucomatous optic neuropathy. The higher resolution of the recently introduced SD-OCT offers enhanced visualization and improved segmentation of the retinal layers, providing a higher accuracy in identification of subtle changes of the optic disc and RNFL thinning associated with glaucoma.
Effect of dietary omega-3 and omega-6 fatty acids on IOP elevation, electroretinographic changes and retinal ganglion cell loss in a rat model of gla…
2008
Purpose To test the efficacy of dietary omega-3 and omega-6 fatty acids in a rat model of glaucoma induced by laser photocoagulation. Methods Rats were fed for 3 months with a diet containing either: 1) 17% of omega-3 fatty acids (10% EPA + 7% DHA), 2) 10% of omega-6 fatty acids (as GLA), or 3) a combination of both omega-3 and omega-6 fatty acids (10% EPA + 7% DHA + 10% GLA), by comparison with a control group of animals fed with a standard diet deprived of EPA, DHA and GLA. After 3 months of diet, glaucoma was induced in one eye of the animal by laser.IOP was regularly measured and the retinal function was evaluated by electroretinography (ERG) for 3 months. At the end of the experiment, …
Macular laser photocoagulation guided by spectral-domain optical coherence tomography versus fluorescein angiography for diabetic macular edema.
2011
Roberto Gallego-Pinazo1,2, Ana Marina Suelves-Cogollos1, Rosa Dolz-Marco1, J Fernando Arevalo3, Salvador García-Delpech1, J Luis Mullor4, Manuel Díaz-Llopis1,2,51Department of Ophthalmology, Hospital Universitario La Fe, Valencia, Spain; 2Centro de Investigación Biomédica en Red de Enfermedades Raras, Valencia, Spain; 3Retina and Vitreous Service, Clinical Ophthalmology Center, Caracas, Venezuela; 4Unit of Experimental Ophthalmology, Hospital Universitario La Fe, Valencia, Spain; 5University of Valencia, Faculty of Medicine, Valencia, SpainBackground: The aim of this study was to compare the efficacy of spectral-domain optical coherence tomography…
Classic Choroidal Neovascularization
2009
Since Donald Gass’s pioneering work in 1967, which demonstrated the role of choroidal neovascularization (CNV) in wet (exudative) AMD, visible (classic) CNV, well demarcated and well-defined on fluorescein angiography, has become the most characteristic form of AMD.
Abduction saccades in unilateral internuclear ophthalmoplegia
1990
Horizontal eye movements were investigated in 60 consecutive patients with unilateral internuclear ophthalmoplegia utilizing direct current electrooculography. In nine patients additional conjugated slowing of ipsiversive saccades indicated the diagnosis of a one-and-a-half syndrome. Slowing of abduction saccades was bilateral in two patients and unilateral in 20 (ipsilateral to the MLF lesion in 17 patients and contralateral in three). Slowing of abduction saccades was attributed to impaired inhibition of the tonic resting activity of the antagonistic medial rectus muscle. On the eye contralateral to the lesion 70% of the patients had abduction nystagmus and 66.7% hy permetric abduction sa…
The electrofunctional investigations in the diagnosis of orbital diseases
1983
The importance of electrofunctional examinations (electroretinography, electro-oculography and visual evoked potentials) in orbital diseases is emphasized. Although such tests cannot give the same support to the clinical diagnosis as ultrasonography or CT scanning, they do give information about the functional state of the various orbital components. Visual evoked potentials can monitor the functionality of the optic nerve during and after trauma or compressive orbital diseases; electroretinography shows retinal changes secondary to traumatic or vascular orbital diseases, while electro-oculography allows to record extraocular muscle dysfunction.
Towards the new spectral-domain optical coherence tomography based classification of age-related macular degeneration
2012
Abstract Introduction Age-related macular degeneration (AMD) is major social and health problem in industrialised societies. The contribution of the new diagnostic techniques, mainly spectral-domain optical coherence tomography (SD-OCT), has led to a better understanding of this disease. Aim To review the current clinical classification of AMD, to describe the new tomographic classification of wet AMD, and to review the new topographical findings in dry AMD. Development There are two classically described forms of AMD: dry and wet; there are also three progressive stages of severity: early, intermediate and advanced. This purely clinical stratification does not take into account any criteri…
Optic neuropathy caused by type A botulinic toxin
2014
Purpose To report the development of an optical neuropathy after injection of type A botulinic toxin in a subject with blepharospasm. Methods Optical neuropathy was evaluated through a complete ophthalmologic examination consisting of bio-microscopy, tonometry and study of visual sharpness, colour test, visual field, OCT, fluorangiography and determination of VEPs. Results Intravenous therapy was begun with Metilprednisolone (20 mg/Kg/day) and Vitamin B6 associated with oral Citicoline, and there was a clear improvement down to normalization of the symptoms. After 6 months the Humphrey computerized visual field with central 30-2 program threshold test emphasised in ODx an upper half-field a…
Zum Einsatz des Ultraschalls in der Diagnostik von Nase und Nasennebenhöhlen
2005
Ultrasound is commonly performed to diagnose pathological processes of the neck and the salivary glands. In contrast, pathological changes of the sinuses and the bony structures of the face are only rarely examined sonographically. This paper deals with the diagnostic scope of ultrasound in the case of orbital and nasal fractures as well as for cases of sinus pathology excluding acute sinusitis. 51 patients with different diseases of this area were examined using US and X-ray or CT scan. Fractures of the nose could all be diagnosed correctly by ultrasound, which is of clinical importance if children or pregnant patients are examined. Blow-out fractures of the orbit were not detected. In con…