Search results for "Genou"
showing 10 items of 610 documents
Frequency-dependent effects of activation and inhibition of protein kinase C on neurohypophysial release of oxytocin and vasopressin
1989
Isolated rat neurohypophyses were superfused in vitro and the release of vasopressin and oxytocin into the medium was determined by specific radioimmunoassays. Hormone secretion was increased by electrical stimulation of the pituitary stalk at different frequencies. The effects of several phorbol esters, known to activate (phorbol 12,13-dibutyrate, PDB) or not to affect (4a-phorbol 12,13-dideconate and phorbol 12-monoacetate) protein kinase C, and of the direct protein kinase C inhibitor 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (H7) were tested. Electrical stimulation with 450 pulses caused the release of about 45 μU vasopressin and 55 μU oxytocin, when a frequency of 3 Hz was applied…
Effects of endotoxin on neurally-mediated gastric acid secretion in the rat.
1998
Abstract The effects of a peripheral administration of E. coli endotoxin on neurally-mediated gastric acid secretion and the role of endogenous opioids or PAF receptors in endotoxin effects have been evaluated in the continuously perfused stomach of the anaesthetized rat. Gastric acid secretion stimulated by distension (20 cm H2O) was reduced dose-dependently by single intravenous bolus injection of endotoxin (0.1–10 μg kg−1). Doses of 5 μg kg−1 induced a peak reduction of distension-stimulated acid output and significantly reduced the secretory response induced by an intravenous bolus of 2-deoxy-d-glucose (150 mg kg−1). This dose of endotoxin did not significantly modify mean systemic arte…
Pan-cancer analysis of whole genomes
2020
Publisher's version (útgefin grein)
Strictly convex variable cost does not imply U-shaped average cost
2016
Abstract We show that strictly convex variable costs do not imply U-shaped average costs and provide a sufficient condition for U-shaped average costs. As an application we study endogenous entry when firms have market power and they have decreasing average cost but increasing marginal cost.
Endogenous timing with infinitely many firms
2008
Abstract A model with constant marginal costs is considered where firms choose first a period for production and then the amount to produce when competing in the market according to the resulting timing decisions. Multiple equilibria arise allowing for infinitely many industry output configurations encompassing one limit-output dominant firm and the Cournot equilibrium with free entry as extreme cases. At each of these equilibria a firm produces a positive amount only if this firm commits to produce at period one. Both Stackelberg and Cournot-like outcomes are sustainable as equilibria however. When the number of leaders is given, production at subsequent periods is always prevented, and in…
Influence of the use of autogenous bone particles to close the access window after maxillary sinus floor augmentation: an experimental study in rabbi…
2020
Abstract Aim To study the influence on the healing of the placement of particulate autogenous bone in the antrostomy and in the subjacent region after maxillary sinus elevation. Material and methods Sixteen New Zealand rabbits were undergone to bilateral maxillary sinus floor augmentation with 4 × 4 mm antrostomy dimension. The sinus mucosa was elevated, and the space obtained was filled with xenograft. In the test site (treated sites), autogenous bone was harvested from the tibia and was placed either in the antrostomy and the subjacent region while the control site was left untreated. Antrostomy was covered bilaterally with collagen membranes. Animals were euthanized after 1 and 8 weeks o…
Freshening of the Mediterranean Salt Giant: controversies and certainties around the terminal (Upper Gypsum and Lago-Mare) phases of the Messinian Sa…
2021
The late Miocene evolution of the Mediterranean Basin is characterized by major changes in connectivity, climate and tectonic activity resulting in unprecedented environmental and ecological disruptions. During the Messinian Salinity Crisis (MSC, 5.97-5.33 Ma) this culminated in most scenarios first in the precipitation of gypsum around the Mediterranean margins (Stage 1, 5.97-5.60 Ma) and subsequently > 2 km of halite on the basin floor, which formed the so-called Mediterranean Salt Giant (Stage 2, 5.60-5.55 Ma). The final MSC Stage 3, however, was characterized by a "low-salinity crisis", when a second calcium-sulfate unit (Upper Gypsum; substage 3.1, 5.55-5.42 Ma) showing (bio)geochemica…
Irrigation Agrosystems in Eastern Spain: Roman or Islamic Origins?
1985
Abstract The long-standing controversy concerning Islamic diffusion of cultivars and irrigation technology to Spain is approached by comparing Roman and Islamic agrosystems at the general, regional, and local levels. We describe the Roman intensification of the older Mediterranean agrosystem and then examine the subsequent agricultural and demographic decline between A.D. 250 and 800. The operation, organization, and evolution of large, intermediate, and small-scale irrigation are analyzed in seven case studies from the Valencia region of eastern Spain. The largest systems were refurbished in Islamic times, but during a period when Berber and Arab settlement was thin and acculturation of th…
Diversity and Distribution of the Dinoflagellates Brachidinium, Asterodinium and Microceratium (Brachidiniales, Dinophyceae) in the open Mediterranea…
2011
Diversity and Distribution of the DinoflagellatesBrachidinium, AsterodiniumandMicroceratium(Brachidiniales, Dinophyceae) in the open Mediterranean SeaBrachidiniacean dinoflagellates have been investigated in the open waters of the Mediterranean Sea, along a transect from the south of France to the south of Cyprus (20 June-18 July 2008).BrachidiniumandKarenia papilionaceaoften co-occurred,B. capitatumpredominating in the surface waters. The highest abundance ofBrachidiniumwere found in the upper 25min the western Mediterranean with amaximum (24 cells L-1) at a depth of 5 m in the Balearic Sea.Asterodinium(up to 4 cells L-1) was recorded below of deep chlorophyll maxima. The genusMicroceratiu…
A Culturally Sensitive Approach to Promoting Initial Literacy Development in Africa : Ongoing and Planned Research and Development at the University …
2017
A four-year research and development program at CAPOLSA (the Centre for the Promotion of Literacy in Sub-Saharan Africa) was inspired by widespread dissatisfaction with poor literacy outcomes of mass basic schooling in Zambia and sought to test the generalizability of a scientifically grounded, computer-mediated instructional resource developed in Finland, for effective intervention in an African society where different linguistic and educational conditions obtain. Specific challenges and opportunities posed by the local sociocultural context included the prevalence of multilingualism, the relatively transparent orthographies of local languages, and poor infrastructure of the public school …