Search results for "Genou"

Depression subtyping based on evolutionary psychiatry: Proximate mechanisms and ultimate functions

2018

Major depressive disorder constitutes one of the leading causes of disability worldwide. However, it is not a unitary disease-it is a heterogeneous syndrome, with patients differing remarkably in symptom profile, pathophysiology and treatment responsiveness. Previous attempts to subtype major depressive disorder have showed limited clinical applicability. We present a classification of major depressive disorder episodes based on the proximate mechanisms that led to the original mood change that caused the depressive episode. We identify discrete depression subtypes that are induced by: 1) infection, 2) long-term stress, 3) loneliness, 4) traumatic experience, 5) hierarchy conflict, 6) grief…

Assessment of clinical outcomes and histomorphometric findings in alveolar ridge augmentation procedures with allogeneic bone block grafts: A systema…

2020

Background This systematic literature review aimed to evaluate the efficacy of allogeneic bone blocks for ridge augmentation by assessing block survival rates and subsequent implant survival, including post-surgical complications and histomorphometric analysis. Material and Methods An electronic and manual search among references, was conducted up to April 2019 by two independent authors. Inclusion criteria were: human clinical trials in which the outcomes of allogeneic bone block grafts were evaluated by means of their survival rates and subsequent implant success rates. Results Seven articles fulfilled the inclusion criteria and were analyzed. A total of 323 allogeneic block grafts were m…

Indigenous Rights

2010

Brain Opioid Activity and Oxidative Injury: Different Molecular Scenarios Connecting Celiac Disease and Autistic Spectrum Disorder

2020

Celiac Disease (CD) is an immune-mediated disease triggered by the ingestion of wheat gliadin and related prolamins from other cereals, such as barley and rye. Immunity against these cereal-derived proteins is mediated by pro-inflammatory cytokines produced by both innate and adaptive system response in individuals unable to adequately digest them. Peptides generated in this condition are absorbed across the gut barrier, which in these patients is characterized by the deregulation of its permeability. Here, we discuss a possible correlation between CD and Autistic Spectrum Disorder (ASD) pathogenesis. ASD can be induced by an excessive and inappropriate brain opioid activity during the neon…

Obesity and functional gait recovery after total hip and total knee arthroplasties : clinical and biomechanical analysis

2018

Introduction : Body Mass Index (BMI) impact on gait recovery after total hip and total knee arthroplasty (THA and TKA) remains misunderstood. Few studies have analyzed the influence of BMI on the recovery of hip and knee range of motion (ROM) during gait or walking speed after THA and TKA. Our objective was to assess this impact preoperatively and post-operatively using both 3D gait analysis and clinical assessment. Our hypothesis was that obesity (BMI> 30kg /m2) would be a negative factor in the recovery of gait parameters.Material and methods: After conducting a systematic review of the literature on functional recovery after total prostheses of the lower limb (THA and TKA) to ensure the …

Zemes dzīļu bagātības Latvijā: KAĻĶAKMENS

2022

Buklets "Zemes dzīļu bagātības Latvijā: KAĻĶAKMENS" iepazīstina ar vienu no Latvijas vērtīgākajiem dabas resursiem, tā daudzveidību un tajā atklātajiem interesantajiem minerāliem. Iekļauta informācija par perma periodā veidojušos kaļķakmeņu pētniecību un atšķirīgajiem pielietojuma veidiem. Bukletu ilustrē Latvijas Universitātes Muzeja Ģeoloģijas kolekciju kaļķakmens paraugu fotogrāfijas.

CHEMICAL INVESTIGATION OF THE INVASIVE ALGA CAULERPA TAXIFOLIA VAR. DISTICHOPHYLLA FROM SICILIAN COASTS

2018

Biological invasions by non-indigenous species have been widely recognized among the most important threats to the integrity of Mediterranean ecosystems, often resulting in huge economic and societal impacts. The success of non-indigenous macrophytes in the new range may be due to a variety of factors such as their vegetative reproductive strategy and synthesis of toxic compounds. These toxic compounds may influence native consumers by reducing their performance with negative implications for their overall grazing activity and, ultimately, for their ability to control the spread of the invasive algae in the new area. In particular, the invasive algae Caulerpa taxifolia (Vahl) C. Agardh (Ct)…

High-intensity interval training and moderate intensity training with exogenous adenosine counteract development of obesity in rats

2022

Objectives High-Intensity Interval Training (HIIT) and Moderate Intensity Training (MIT) can combat the obesity epidemic. However, studies comparing their effects on obesity show controversial findings regarding weight loss. Adenosine has emerged as a possible, novel therapeutic agent to treat obesity, but more preclinical studies on its efficacy are needed. Therefore, the objectives of this study were to compare the effects of HIIT and MIT on obesity, and further to determine the dose-dependent effects of adenosine on body weight. Equipment and methods We induced obesity in male Wistar rats with high-fat diet (HFD) and monitored development of obesity by comparing the weight to rats on nor…

Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity

2021

Centrioles comprise the heart of centrosomes, microtubule-organizing centers. To study the function of centrioles in lung and gut development, we genetically disrupted centrioles throughout the mouse endoderm. Surprisingly, removing centrioles from the endoderm did not disrupt intestinal growth or development but blocked lung branching. In the lung, acentriolar SOX2-expressing airway epithelial cells apoptosed. Loss of centrioles activated p53, and removing p53 restored survival of SOX2-expressing cells, lung branching, and mouse viability. To investigate how endodermal p53 activation specifically killed acentriolar SOX2-expressing cells, we assessed ERK, a prosurvival cue. ERK was active t…

Ceramic Production in the Indigenous Settlement of Entella (Western Sicily) During the Archaic Age

2010

Indigenous fine tablewares (both plain and with painted geometric patterns/decorations) were widely diffused in western and central Sicily between the seventh and the fifth centuries BC (Gargini 1995; Spatafora 1996; Trombi 1999; Campisi 2003 However, the considerable recurrence of shapes and decorative subjects inhibits the identification of specific production centres merely on the basis of stylistic and morphological analyses. Therefore, the extent of the distribution of objects manufactured in different workshops cannot be fully appreciated, and the network of ceramic trade in Archaic Sicily is acknowledged only in terms of the relationships between the Phoenician and Greek colonies and…