Search results for "Geriatrics"

showing 10 items of 1388 documents

Comment on “Sleep disturbances and later cognitive status: a multi-centre study”

2018

To investigate the associations between sleep disturbances in mid-life and late-life and late-life cognitive status.In four population-based studies (three Swedish studies: H70 study, Kungsholmen Project (KP) and The Swedish Panel Study of Living Conditions of the Oldest Old (SWEOLD); and one Finnish study: Cardiovascular Risk Factors, Aging and Dementia (CAIDE)), participants provided self-reports on insomnia, nightmares and general sleep problems. Late-life cognitive status was measured by the Mini Mental State Exam (MMSE). The associations between late-life sleep disturbances and cognition 3-11 years later were investigated across all studies (n = 3210). Mean baseline ages were 70 (CAIDE…

MaleSleep Wake Disordersmedicine.medical_specialtyDisease03 medical and health sciencesCognition0302 clinical medicinePhysical medicine and rehabilitationRisk FactorsSleep Initiation and Maintenance DisordersHumansMedicineDementiaCircadian rhythmRisk factorFinlandAgedSlow-wave sleepAged 80 and overSweden030214 geriatricsbusiness.industryEye movementSleep disturbancesGeneral MedicineMental Status and Dementia Testsmedicine.diseaseSleep in non-human animalsEditorialCognitive impairmentAgeingFemaleSettore MED/26 - NeurologiaSelf Reportbusiness030217 neurology & neurosurgeryAnnals of Translational Medicine
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Antipsychotic prescription and mortality in hospitalized older persons

2016

Background: Recent scientific reports have shown that older persons treated with antipsychotics for dementia-related behavioural symptoms have increased mortality. However, the impact of these drugs prescribed during hospitalization has rarely been assessed. We aimed to investigate whether antipsychotics are associated with an increased risk of mortality during hospitalization and at 3-month follow-up in elderly inpatients. Methods: We analyzed data gathered during two waves (2010 and 2012) by the REPOSI (Registro Politerapie Società Italiana Medicina Interna). All new prescriptions of antipsychotic drugs during hospitalization, whether maintained or discontinued at discharge, were collect…

MaleSocio-culturaleOlder personAntipsychoticCognitionEconomicaAntipsychotics; Hospitalization; Mortality; Older persons; Gerontology; Geriatrics and Gerontology; Psychiatry and Mental HealthHumansMortalityPsychomotor AgitationAgedantipsychotics hospitalization mortality older personsAged 80 and overMental DisordersPatient DischargeHospitalizationantipsychoticsItalyantipsychotics; hospitalization; mortality; older personsPsychiatry and Mental Healtholder personsDementiaFemaleGeriatrics and GerontologyGerontologyAntipsychotic Agents
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Specific patterns of laryngeal electromyography during wakefulness are associated to sleep disordered breathing and nocturnal stridor in multiple sys…

2016

Abstract Background Nocturnal stridor and respiratory abnormalities are important features of multiple system atrophy (MSA) with relevance to patient survival, and they are detected and evaluated mainly through video-polysomnography (video-PSG). Diurnal laryngoscopy seems to yield abnormal findings only in the presence of significant vocal cord (VC) dysfunction. Aim To assess whether specific electrophysiological patterns of diurnal EMG of VC muscles may indicate nocturnal stridor or respiratory dysfunctions in MSA patients. Materials and methods Seventeen patients with probable MSA were examined. A full-night video-PSG to collect standard breathing parameters (apnea/hypopnea index, mean Hb…

MaleStridorPolysomnographyLaryngoscopySeverity of Illness Index03 medical and health sciences0302 clinical medicineAtrophySleep Apnea SyndromesmedicineHumansRespiratory systemWakefulness030223 otorhinolaryngologyAgedRespiratory Soundsmedicine.diagnostic_testbusiness.industryElectromyographyApneaEMG abnormalityMiddle AgedMultiple System Atrophymedicine.diseasenervous system diseasesrespiratory tract diseasesCircadian RhythmNeurologyAnesthesiaWakefulnessFemaleNeurology (clinical)Geriatrics and Gerontologymedicine.symptomLaryngeal MusclesbusinessHypopnea030217 neurology & neurosurgeryParkinsonismrelated disorders
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Measuring elderly people's quality of life through the Beck Hopelessness Scale: a study with a Spanish sample.

2016

Hopelessness is a key element of suicidal intent. It can instill a pessimistic outlook on the future, leading an individual to believe that suicide is the only answer to their problems. Hopelessness operates as a modulating variable between depression and suicidal behavior. The aim of this study was to confirm the factor structure of the Beck Hopelessness Scale (BHS) in a non-clinical sample.Three hundred and sixty-two Spanish individuals, aged over 60, free of cognitive impairment and depressive symptoms, completed the BHS scale. Participants were tested using confirmatory factor analysis (CFA), using one-, two- and three-factor models.The one- and two-factor models presented adequate fit …

MaleSuicide PreventionAgingPsychometricsmedia_common.quotation_subjectPoison controlPessimismSuicide preventionFrustrationSuicidal Ideation03 medical and health sciences0302 clinical medicineQuality of life (healthcare)Injury preventionHumansmedia_commonAgedPsychiatric Status Rating ScalesMotivationDepressionHuman factors and ergonomicsReproducibility of ResultsMiddle AgedhumanitiesConfirmatory factor analysis030227 psychiatryPsychiatry and Mental healthSuicideEarly DiagnosisSpainBeck Hopelessness ScaleQuality of LifeFemaleGeriatrics and GerontologyPshychiatric Mental HealthPsychologyFactor Analysis StatisticalGerontology030217 neurology & neurosurgeryClinical psychologyAgingmental health
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White blood cell counts as risk markers of developing metabolic syndrome and its components in the Predimed study.

2013

Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; TRIAL REGISTRATION Controlled-Trials.comISRCTN35739639. BACKGROUND The Metabolic Syndrome (MetS) is a cluster of metabolic abnormalities that includes hyperglucemia, hypertension, dyslipidemia and central obesity, conferring an increased risk of cardiovascular disease. The white blood cell (WBC) count has been proposed as a marker for predicting cardiovascular risk. However, few prospective studies have evaluated the relationship between WBC subtypes and risk of MetS. METHODS Participants were recruited from seven PREDIMED study centers. Both a baseline cross-sectional (n = 4,377) and a prospe…

MaleSíndrome metabòlicaMediterranean dietNeutrophilsEpidemiologyEstudios transversalesMetabolic disorders:Named Groups::Persons::Age Groups::Adult::Aged::Aged 80 and over [Medical Subject Headings]Disease:Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]Diet Mediterranean:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Leukocyte CountLymphocitesRisk FactorsBlood plasmaPathologyMedicineProspective StudiesProspective cohort studyAged 80 and overMetabolic SyndromeClinical ChemistryMultidisciplinary:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Nutrition Therapy::Diet Therapy::Diet Mediterranean [Medical Subject Headings]QRMiddle AgedMetabolic syndromeClinical Laboratory Sciences1932-6203:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings]medicine.anatomical_structureCholesterolCardiovascular diseasesCardiovascular DiseasesMedicineWhite blood cellsFemalePublic HealthEnfermedades cardiovascularesResearch Articlemedicine.medical_specialty:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Prospective Studies [Medical Subject Headings]Recuento de linfocitosScience:Check Tags::Male [Medical Subject Headings]Mediterranean cookingDiagnostic MedicineInternal medicineWhite blood cell:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Cell Count::Blood Cell Count::Leukocyte Count::Lymphocyte Count [Medical Subject Headings]Cuina mediterràniaHumansLymphocyte CountObesity:Named Groups::Persons::Age Groups::Adult::Aged [Medical Subject Headings]:Diseases::Cardiovascular Diseases [Medical Subject Headings]Cardiovascular Disease EpidemiologyAged:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Metabolic Syndrome X [Medical Subject Headings]business.industryMalalties cardiovascularsRecuento de leucocitosSíndrome X metabólicomedicine.diseaseObesityLong-Term CareDieta mediterránea:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Cell Count::Blood Cell Count::Leukocyte Count [Medical Subject Headings]Biomarker EpidemiologyCross-Sectional Studies:Check Tags::Female [Medical Subject Headings]GeriatricsImmunologyClinical ImmunologyPreventive MedicineMetabolic syndrome:Anatomy::Cells::Blood Cells::Leukocytes::Granulocytes::Neutrophils [Medical Subject Headings]businessDyslipidemiaBiomarkersGeneral Pathology
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Prevalence and Risk Factors Associated with Use of QT-Prolonging Drugs in Hospitalized Older People

2016

Aims: The objective of this study was to evaluate the prevalence of the prescription of QT-prolonging drugs at hospital admission and discharge and the risk factors associated with their use in older people (aged 65 years and older). Methods: Data were obtained from the REPOSI (REgistro POliterapie SIMI [Società Italiana di Medicina Interna]) registry, which enrolled 4035 patients in 2008 (n = 1332), 2010 (n = 1380), and 2012 (n = 1323). Multivariable logistic regression was performed to determine the risk factors independently associated with QT-prolonging drug use. QT-prolonging drugs were classified by the risk of Torsades de Pointes (TdP) (definite, possible, or conditional) acc…

MaleTORSADES-DE-POINTES INTERVAL PROLONGATION PATIENT CIPROFLOXACIN COHORT DEATH MULTIMORBIDITY AMIODARONE MORTALITY AIFA.Amiodarone030204 cardiovascular system & hematologyCIPROFLOXACINLogistic regressionAmiodaroneElectrocardiography0302 clinical medicineRisk FactorsTorsades de PointesAtrial Fibrillation80 and overPrevalencePharmacology (medical)030212 general & internal medicineAged; Aged 80 and over; Amiodarone; Atrial Fibrillation; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Middle Aged; Patient Discharge; Prevalence; Risk Factors; Torsades de Pointes; Hospitalizationmedia_commonAged 80 and overTorsades de PointeAged; Aged 80 and over; Amiodarone; Atrial Fibrillation; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Middle Aged; Patient Discharge; Prevalence; Risk Factors; Torsades de Pointes; Hospitalization; Pharmacology (medical); Geriatrics and Gerontology; Medicine (all)Medicine (all)DEATHMiddle AgedPatient DischargeHospitalizationLong QT SyndromeCohortHospitalized Older PeopleFemalemedicine.drugHumanDrugmedicine.medical_specialtymedia_common.quotation_subjectMULTIMORBIDITYTorsades de pointesPATIENT03 medical and health sciencesPharmacotherapyInternal medicineINTERVAL PROLONGATIONmedicineHumansTORSADES-DE-POINTESCOHORTMedical prescriptionAIFAAgedbusiness.industryMORTALITYRisk FactorSettore MED/09 - MEDICINA INTERNAOdds ratiomedicine.diseaseQT-Prolonging DrugAged; Aged 80 and over; Amiodarone; Atrial Fibrillation; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Middle Aged; Patient Discharge; Prevalence; Risk Factors; Torsades de Pointes; Hospitalization; Geriatrics and Gerontology; Pharmacology (medical)Physical therapyGeriatrics and Gerontologybusiness
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Life-review therapy with computer supplements for depression in the elderly: A randomized controlled trial

2012

Life-review therapy has been recognized as an effective therapeutic approach for depression in older adults. Additionally, the use of new media is becoming increasingly common in psychological interventions. The aim of this study was to investigate a life-review therapy in a face-to-face setting with additional computer use. This study explored whether a six-week life-review therapy with computer supplements from the e-mental health Butler system constitutes an effective approach to treat depression in older adults aged 65 and over. A total of 36 participants with elevated levels of depressive symptoms were randomized to a treatment group or a waiting-list control group and completed the po…

MaleTime Factors2921 Psychiatric Mental HealthPsychological intervention2717 Geriatrics and GerontologyPersonal Satisfactionlaw.inventionLife Change Events2738 Psychiatry and Mental HealthPsychotherapeutisches Zentrum des Psychologischen Instituts UZHe-mental healthTherapeutic approachQuality of lifeRandomized controlled trialBehavior TherapyMemorylawGermanySurveys and QuestionnairesReminiscenceHumansLife-reviewolder adultsDepression (differential diagnoses)AgedAged 80 and overComputers10093 Institute of PsychologyDepressionLife satisfaction2909 GerontologySelf ConceptPsychiatry and Mental healthTreatment OutcomeQuality of LifeFemaleSelf ReportGeriatrics and GerontologyPshychiatric Mental Health150 PsychologyPsychologyGerontologyLife reviewFollow-Up StudiesClinical psychologyAging & Mental Health
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Maximum bite force after the replacement of complete dentures.

2001

In complete denture wearers the maximum bite force (MBF) is known to be considerably lower than in dentate people. Low MBF might therefore be an indication of poor denture fit but there is limited evidence on this. Therefore, the aim of the present study was to investigate whether MBF can be improved by the replacement of complete dentures for elderly people. Nine edentulous volunteers, average age 74·2 ± 5·5 years and average denture experience 19·4 ± 19·5 years (1–50 years), had replacement dentures made. Functional impressions were taken after border moulding using zinc oxide eugenol paste. After a rehearsal session, MBF was recorded with the old dentures, and with the new dentures immed…

MaleTime Factorsmedicine.medical_treatmentTransducersDentistryPilot ProjectsBone resorptionStatistics NonparametricBite Forcechemistry.chemical_compoundSex FactorsmedicineElderly peopleHumansJaw EdentulousMandibular DiseasesLimited evidenceBone ResorptionBite strengthDenture DesignGeneral DentistryAgedDenture Completebusiness.industryAge FactorsSignal Processing Computer-AssistedPoint methodResorptionBite force quotientchemistryDenture DesignZinc oxide eugenolFemaleGeriatrics and GerontologyDenturesbusinesscirculatory and respiratory physiologyFollow-Up StudiesGerodontology
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Association Between Platelet Endothelial Cellular Adhesion Molecule-1 Polymorphisms and Atherosclerosis: Results of a Study on Patients from Northern…

2010

Adhesion of circulating cells to the arterial surface is among the first detectable events in atherogenesis. Cellular adhesion molecules, expressed by the vascular endothelium and by circulating leukocytes, mediate cell recruitment and their transendothelial migration. Platelet endothelial cellular adhesion molecule-1 (PECAM-1), involved in this migration, has been associated with the development of atherosclerosis. Studies have investigated an association between coronary artery disease (CAD) and single-nucleotide polymorphisms (SNPs) located in functionally important domains of the PECAM-1 gene with inconsistent results. Thus, we have analyzed the distribution of V125L, N563S, and G670R S…

MaleUntranslated regionAgingGenotypeSingle-nucleotide polymorphismCoronary Artery DiseaseBiologyPolymorphism Single NucleotideCoronary artery diseaseGene FrequencymedicineHumansGenetic Predisposition to DiseasePlateletCell adhesionGeneAgedCell adhesion moleculeAdhesionMiddle AgedAtherosclerosismedicine.diseasePlatelet Endothelial Cell Adhesion Molecule-1ItalyCase-Control StudiesImmunologycardiovascular systemFemaleGeriatrics and GerontologyRejuvenation Research
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Psychometric properties of the 10-item Connor–Davidson resilience scale among Finnish older adults

2021

Objectives: Resilience, the ability to bounce back after adverse events may be an important factor in active aging. The 10-item version of the Connor–Davidson Resilience Scale (CD-RISC10) seems suitable for aging research owing to its low participant burden; however, its psychometric properties have not been comprehensively reported for older people. For example, no estimate exists of the test–retest reliability of the scale when used with older adults. Hence, this study evaluated the psychometric properties of the CD-RISC10 in a large population-based sample of community-dwelling older people. Method: The scale’s internal consistency, factor structure, construct validity, test-retest relia…

MaleValidation studyPsychometricspsychometric properties03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesHumansResilience (network)resilienceFinlandreliabiliteettiAgedresilienssi030214 geriatricsagingReproducibility of ResultsResilience PsychologicalpsykometriikkaPsychiatry and Mental healthikääntyminenvalidation studyvaliditeettimittarit (mittaus)CD-RISCFemaleResilience scaleConnor-Davidson Resilience ScaleGeriatrics and GerontologyPshychiatric Mental HealthFactor Analysis StatisticalPsychologyGerontologyikääntyneet030217 neurology & neurosurgeryClinical psychologyAging & Mental Health
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