Search results for "Germany"

showing 10 items of 1172 documents

Survival and reinterventions after isolated proximal aortic repair in acute type A aortic dissection.

2018

OBJECTIVES Conventional treatment for acute type A dissection is the replacement of the ascending aorta. This study demonstrates the results of a conventional approach with isolated proximal repair combined with concomitant endovascular procedures. METHODS Replacement of the ascending aorta with or without an open distal anastomosis was defined as isolated proximal repair and was performed in 562/588 patients between January 2004 and June 2017. A total of 68% were DeBakey type I and 32% were DeBakey type II aortic dissections. Concomitant procedures were thoracic endovascular aortic repair (3.6%); visceral, renal and iliac stents (2%); and peripheral bypasses (1.1%). Mean follow-up was 4.6 …

Pulmonary and Respiratory MedicineMaleReoperationmedicine.medical_specialtyAorta Thoracic030204 cardiovascular system & hematologylaw.inventionCoronary artery disease03 medical and health sciences0302 clinical medicinePostoperative ComplicationslawRisk Factorsmedicine.arteryGermanyAscending aortamedicineCardiopulmonary bypassHumansHospital MortalitySurvival rateAgedAortic dissectionAortic Aneurysm Thoracicbusiness.industryMortality rateIncidenceEndovascular ProceduresMiddle Agedmedicine.diseaseSurgerySurvival RateDissectionAortic DissectionTreatment Outcome030228 respiratory systemConcomitantSurgeryFemaleCardiology and Cardiovascular MedicinebusinessInteractive cardiovascular and thoracic surgery
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German registry for acute aortic dissection type A (GERAADA)--lessons learned from the registry.

2010

A German registry for acute aortic dissection type A (GERAADA) was initiated by the Working Group for Aortic Surgery and Interventional Vascular Surgery of the German Society for Thoracic and Cardiovascular Surgery (GSTCVS) in July 2006. This web-based database was developed to record the data of patients who had undergone surgery for aortic dissection type A. From analyzing the data, we aim to learn how to improve surgical treatment and to identify parameters affecting patient outcome. In the beginning, 33 cardiac centers participated via online access to the registry on the GSTCVS' homepage. Since then, 43 centers in Germany, Switzerland and Austria have begun entering data on the pre- an…

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtyMEDLINERisk AssessmentGermanBlood Vessel Prosthesis ImplantationAneurysmGermanymedicineHumansRegistriesSurgical treatmentSocieties MedicalAortic dissectionInternetbusiness.industryGeneral surgeryPatient SelectionVascular surgeryMiddle Agedmedicine.diseaseAortic surgerylanguage.human_languageAortic AneurysmAortic DissectionTreatment OutcomeMulticenter studyAustriaAcute DiseaselanguageSurgeryFemaleMedical emergencyCardiology and Cardiovascular MedicinebusinessSwitzerlandThe Thoracic and cardiovascular surgeon
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C-reactive Protein Levels After Esophagectomy Are Associated With Increased Surgical Trauma and Complications.

2020

With the introduction of minimally invasive esophagectomy, postoperative complications rates have decreased. Daily laboratory tests are used to screen patients for postoperative complications. The course of inflammatory indicators after esophagectomy after different surgical approaches has not been described yet. The aim of the study was to describe the postoperative C-reactive protein (CRP) and leukocyte levels after different surgical approaches for esophagectomy and relate it to postoperative complications.Between 2010 and 2018, 217 consecutive patients underwent thoracoabdominal esophagectomy with gastric conduit reconstruction. Blood tests to assess CRP and leukocytes were performed da…

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtyMultivariate analysisEsophageal Neoplasmsmedicine.medical_treatment030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicinePostoperative ComplicationsGermanyBiomarkers TumorMedicineHumansMinimally Invasive Surgical ProceduresPostoperative PeriodMinimally invasive proceduresRetrospective StudiesSurgical approachbiologybusiness.industryGastric conduitIncidence (epidemiology)IncidenceC-reactive proteinRetrospective cohort studyMiddle AgedSurgeryEsophagectomyC-Reactive Protein030228 respiratory systemEsophagectomybiology.proteinSurgeryFemaleCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesThe Annals of thoracic surgery
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Feasibility of transcatheter aortic valve implantation in patients with coronary heights ≤7 mm: insights from the transcatheter aortic valve implanta…

2018

OBJECTIVES Transcatheter aortic valve implantation (TAVI) in patients with low coronary heights is generally denied but is not impossible. Information about these high-risk procedures is sparse. METHODS Since May 2008, data of more than 3000 patients who had TAVI were prospectively collected in the institutional TAVI Karlsruhe registry. Characteristics, peri- and postoperative outcome of patients with low coronary heights of ≤7 mm were analysed according to the Valve Academic Research Consortium-2. RESULTS Eighty-six patients with an average coronary height of 6.4 ± 1.1 mm (mean age 81.0 ± 5.3 years, logistic EuroSCORE I 19.6 ± 13.3%) were treated. TAVI was performed in 72 transfemoral (83.…

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtymedicine.medical_treatment030204 cardiovascular system & hematologyCoronary AngiographyTranscatheter Aortic Valve Replacement03 medical and health sciences0302 clinical medicinePostoperative ComplicationsValve replacementGermanyMedicineHumans030212 general & internal medicineProspective StudiesRegistriesProspective cohort studyAortic dissectionAged 80 and overBioprosthesisbusiness.industryMortality rateIncidenceHazard ratioExtracorporeal circulationPercutaneous coronary interventionGeneral MedicineAortic Valve Stenosismedicine.diseaseCoronary VesselsSurgerySurvival RateTreatment OutcomeCoronary OcclusionCoronary occlusionAortic ValveFluoroscopyFeasibility StudiesSurgeryFemaleCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
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Eligibility for treatment with omalizumab in Italy and Germany.

2013

Summary Omalizumab is an add-on therapy for patients with uncontrolled severe allergic asthma. In Europe, patients must fulfil a number of additional criteria to become eligible for omalizumab therapy, creating a challenge for epidemiology studies to quantify the potential patient pool. Thus, and in the absence of robust data, the number of omalizumab-eligible patients has remained unclear. To assess eligible patient numbers, a chart-audit design approach was employed to measure epidemiology variables based on patient-level data. 770 patient charts were reviewed in designated towns in Germany and Italy, in collaboration with >200 primary care physicians (PCPs) and respiratory specialists (R…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyPediatricsReferralEpidemiologySevere asthmaAllergic asthmaEligibility DeterminationOmalizumabPrimary careOmalizumabAntibodies Monoclonal HumanizedSeverity of Illness IndexAntibodiesSampling StudiesDose-Response RelationshipProduct LabelGermanyEpidemiologyMonoclonalmedicinePrevalenceHumansNational levelAnti-Asthmatic AgentsHumanizedAnti-immunoglobulin EEligibilityDose-Response Relationship Drugbusiness.industryPatient SelectionAllergic asthmaImmunoglobulin EAsthmaAntibodies Anti-IdiotypicAnti-IdiotypicTreatment OutcomeItalyQuality of LifeBiological MarkersDrugbusinessBiomarkersmedicine.drugAllergic asthma; Anti-immunoglobulin E; Eligibility; Epidemiology; Anti-Asthmatic Agents; Antibodies Anti-Idiotypic; Antibodies Monoclonal Humanized; Asthma; Biological Markers; Dose-Response Relationship Drug; Eligibility Determination; Germany; Humans; Immunoglobulin E; Italy; Patient Selection; Prevalence; Quality of Life; Sampling Studies; Severity of Illness Index; Treatment OutcomeRespiratory medicine
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German Registry for Acute Aortic Dissection Type A (GERAADA)--new software design, parameters and their definitions.

2011

BACKGROUND The working group for aortic surgery and interventional vascular surgery of the German Society for Thoracic and Cardiovascular Surgery (GSTCVS) initiated the web-based German Registry for Acute Aortic Dissection type A (GERAADA). It is the project's aim to collect standardized data from a large pool of patients with acute aortic dissections type A (AADA) to gain a deeper insight and knowledge to improve surgical therapies and perioperative management for these patients in the future. METHODS In addition to new medical insights, the working group has gained more experience over the last 4 years in how to collect valid and high-quality data. This experience led us to revise the dat…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyTime FactorsInformation Storage and RetrievalGermanUser-Computer InterfaceSoftware DesignGermanyTerminology as TopicmedicineHumansMulticenter Studies as TopicRegistriesQuality Indicators Health CareAortic dissectionInternetPerioperative managementAcute aortic dissectionsbusiness.industryEndovascular ProceduresVascular surgerymedicine.diseaseAortic surgerylanguage.human_languageSurgeryAortic AneurysmAortic DissectionOutcome and Process Assessment Health CareTreatment OutcomeAustriaAcute DiseaselanguageSoftware designSurgeryMedical emergencyCardiology and Cardiovascular MedicinebusinessVascular Surgical ProceduresSwitzerlandThe Thoracic and cardiovascular surgeon
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German Thoracic Research Scholarship 1996: lung volume reduction for endstage pulmonary emphysema at the Washington University of St. Louis.

1998

The Thoracic Research Scholarship 1996 of the German Society for Thoracic and Cardiovascular Surgery enabled me to visit Barnes Hospital at the Washington University of St. Louis, USA, from May to July 1996. At that center Prof. J. D. Cooper has established lung-volume reduction surgery as a successful surgical treatment for patients with endstage pulmonary emphysema. The operation is performed using left-sided double-lumen intubation. After opening of the chest and pleura and starting single-lung ventilation the less diseased parts of the second lung collapse due to absorption atelectasis whereas the more diseased portion of the lung stays hyperinflated. Linear staplers buttressed with bov…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyUniversitiesmedicine.medical_treatmentPulmonary emphysemaAtelectasisGermanyPreoperative CaremedicineIntubationAnimalsHumansLung volumesLung Diseases ObstructiveFellowships and ScholarshipsPneumonectomySocieties MedicalLungMissouribusiness.industryPerioperativerespiratory systemLength of Staymedicine.diseasePrognosisrespiratory tract diseasesSurgerySt louismedicine.anatomical_structureTreatment OutcomePulmonary EmphysemaBreathingSurgeryCattleCardiology and Cardiovascular MedicinebusinessThe Thoracic and cardiovascular surgeon
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Postoperative non-invasive assessment of pulmonary vascular resistance using Doppler echocardiography.

2011

Non-invasive monitoring of pulmonary vascular resistance (PVR) in postoperative cardiac surgery patients might be useful, particularly for management of pulmonary hypertension. For this purpose, we sought to assess Doppler echocardiography in the intensive care setting. In 73 patients, hemodynamics was measured using both, invasive gold standard (pulmonary artery catheter), and non-invasively by Doppler echocardiography. Four Doppler parameters: (1) tricuspid regurgitant velocity/time-velocity-integral of right ventricular outflow tract (TRV/VTI(RVOT)), (2) tricuspid annular systolic velocity (S'), (3) tricuspid annular strain, and (4) tricuspid annular strain rate, were compared with invas…

Pulmonary and Respiratory Medicinemedicine.medical_specialtymedicine.medical_treatmentHypertension PulmonaryBlood PressureDoppler echocardiographyPulmonary ArterySensitivity and SpecificityVentricular Function LeftPredictive Value of TestsInternal medicineIntensive careGermanymedicineVentricular outflow tractHumansFamilial Primary Pulmonary Hypertensioncardiovascular diseasesSystoleCardiac Surgical ProceduresPulmonary wedge pressureAgedAged 80 and overPostoperative CareChi-Square Distributionmedicine.diagnostic_testbusiness.industryPulmonary artery catheterMiddle Agedmedicine.diseasePulmonary hypertensionEchocardiography DopplerIntensive Care Unitsmedicine.anatomical_structureCatheterization Swan-Ganzcardiovascular systemVascular resistanceCardiologyLinear ModelsVentricular Function RightSurgeryVascular ResistanceTricuspid ValveCardiology and Cardiovascular MedicinebusinessInteractive cardiovascular and thoracic surgery
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Perinatal Database in Germany

1995

By collecting standardized data from up to 600,000 deliveries per year in Germany a nation-wide database has been established in recent years enabling not only regional and overregional quality control, but also the scientific analysis of rare maternal and fetal complication. During the observation period of 10 years the understanding of perinatal risk factors has considerably improved and the perinatal mortality has declined from 9.4 to 6.4 (per 1,000 deliveries). From the huge amount of calculations typical results are presented.

Quality ControlDatabasebusiness.industryPerinatal mortalityObservation periodInfant NewbornObstetrics and GynecologyPerinatal riskcomputer.software_genrePregnancy ComplicationsPerinatal CareScientific analysisPregnancyRisk FactorsGermanyInfant MortalityHumansMedicineFemalebusinessComplicationcomputerInformation SystemsJournal of Obstetrics and Gynaecology
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Influences of heat seal lacquer thickness on the quality of blister packages.

2011

A sealability of aluminium lidding foils against formable polymer materials of blister packages is usually achieved by a coating of aluminium with certain grammages of heat seal lacquers. To investigate influences of their thickness on quality of blister packages, lidding foils with different grammages of two lacquer types were manufactured. Sealing experiments (variation of temperature, pressure and sealing time) were performed. Sealed seam strengths were determined with mechanical tensile tests, tightness of cold form blisters were analysed by means of helium leakage tests. Time-dependent moisture uptake of stored blisters was monitored with micro-gas chromatography. By means of a simple …

Quality ControlGrammageMaterials scienceTime FactorsChemical PhenomenaSurface PropertiesPharmaceutical Sciencechemistry.chemical_elementengineering.materialPermeabilityLacquerchemistry.chemical_compoundCoatingAluminiumGermanyTensile StrengthUltimate tensile strengthMaterials TestingmedicinePressureComposite materialPolyvinyl ChlorideLacquerDrug Packagingintegumentary systemMoistureTemperatureWaterBlistersPolyvinyl chloridechemistryModels Chemicalvisual_artvisual_art.visual_art_mediumengineeringmedicine.symptomAlgorithmsEuropean journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
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