Search results for "Glia"

Il fenomeno delle dipendenze patologiche: alcol e droghe illecite. Protocollo di analisi delle sostanze di abuso nei liquidi biologici con finalità d…

2011

Le tecniche grafiche

2015

Il capitolo presenta il tema delle tecniche grafiche nella valutazione psicodiagnostica in età evolutiva. In particolare vengono descritte le tecniche di analisi del disegno dell'albero, della figura umana e della famiglia negli aspetti della somministrazione e della valutazione in diversi contesti clinici.

Pharmacogenomic identification of small molecules for lineage specific manipulation of subventricular zone germinal activity

2017

Strategies for promoting neural regeneration are hindered by the difficulty of manipulating desired neural fates in the brain without complex genetic methods. The subventricular zone (SVZ) is the largest germinal zone of the forebrain and is responsible for the lifelong generation of interneuron subtypes and oligodendrocytes. Here, we have performed a bioinformatics analysis of the transcriptome of dorsal and lateral SVZ in early postnatal mice, including neural stem cells (NSCs) and their immediate progenies, which generate distinct neural lineages. We identified multiple signaling pathways that trigger distinct downstream transcriptional networks to regulate the diversity of neural cells …

The pattern of neuroblast formation, mitotic domains and proneural gene expression during early brain development in Drosophila.

2003

In the Drosophila embryo, studies on CNS development have so far mainly focused on the relatively simply structured ventral nerve cord. In the trunk, proneural genes become expressed in small cell clusters at specific positions of the ventral neuroectoderm. A lateral inhibition process mediated by the neurogenic genes ensures that only one cell within each proneural cluster delaminates as a neural stem cell (neuroblast). Thus, a fixed number of neuroblasts is formed, according to a stereotypical spatiotemporal and segmentally repeated pattern, each subsequently generating a specific cell lineage. Owing to higher complexity and hidden segmental organisation, the mechanisms underlying the dev…

Notch and Numb are required for normal migration of peripheral glia in Drosophila

2006

Abstract A prominent feature of glial cells is their ability to migrate along axons to finally wrap and insulate them. In the embryonic Drosophila PNS, most glial cells are born in the CNS and have to migrate to reach their final destinations. To understand how migration of the peripheral glia is regulated, we have conducted a genetic screen looking for mutants that disrupt the normal glial pattern. Here we present an analysis of two of these mutants: Notch and numb. Complete loss of Notch function leads to an increase in the number of glial cells. Embryos hemizygous for the weak NotchB-8X allele display an irregular migration phenotype and mutant glial cells show an increased formation of …

Sonic hedgehog promotes the migration and proliferation of optic nerve oligodendrocyte precursors.

2007

Optic nerve (ON) oligodendrocyte precursors (OPCs) are generated under the influence of the Sonic hedgehog (Shh) in the preoptic area from where they migrate to colonise the entire nerve. The molecular events that control this migration are still poorly understood. Recent studies suggested that Shh is often used by the same cell population to control different processes, including cell proliferation and migration, raising the possibility that Shh could contribute to these aspects of OPC development. In support of this idea, we show here that Shh induces the proliferation of OPCs derived from embryonic mouse ON explants and acts as a chemoattractant for their migration. In ovo injections of …

Strutture preesistenti come appoggio per le absidi a Cagliari nel XIV secolo

2015

The paper addresses the issue of the reuse of existing structures as a starting point for the construction of churches, paying particular attention to religious architecture built in Cagliari starting from the 1320s. The study focused in particular on some churches whose apses were built exploiting the presence of earlier defensive structures either abandoned or damaged during the Aragonese siege of Cagliari Castle (1324-26). As suggested by evidence found in the built-up architecture, in the architectural production after the Aragonese conquest of the city it is possible to find traces of a building strategy that involved the reuse of abandoned towers for the construction of apses, convert…

Preliminary results of fault-related permeability structures associated in the Scicli-Ragusa fault, Hyblean Plateau, Sicily.

2010

Il diritto di famiglia in Europa. Plurimi e simili o plurimi e diversi

2012

Apparati

2011

Amato, Giacomo: 32, 33. Basile, Ernesto: 17, 150, 161, 164, 170 nota 64, 171 nota 79, 172 nota 87. Basta, Scipione: 29, 30, 45 nota 47, 46 e ivi nota 51. Bocia, Innocenzo (anche Innocensus): 77. Boito, Camillo: 17. Cascione, Giovan Battista: 31, 32, 34. Chenchi, Carlo: 91, 93, 100 nota 77. Chiavetta Gaetano (anche Caietanus Chivetto): 77, 87.