Search results for "Glia"

Epilogo

2008

Breve riflessione a margine del volume sulle dinamiche di capitalizzazione delle risorse personali nella progettazione di politiche di welfare su base locale.

Scomposizione della disuguaglianza socio-economica della salute: analisi dei dati EU-SILC 2010 sulle condizioni di vita delle famiglie

RENDITE IMPUTATE E DISUAGUAGLIANZE DEI REDDITI:UN’ANALISI EMPIRICA SULLE FAMIGLIE ITALIANE

2009

Le condizioni di vita delle famiglie vengono generalmente influenzate da una molteplicità di fattori non tutti rigorosamente monetari, ma che possono esercitare ugualmente un effetto rilevante sul livello di benessere. Mentre la letteratura internazionale si è più volte interrogata sull’impatto delle componenti monetarie del reddito sulle disuguaglianze di reddito, lo stesso non può dirsi per le componenti non monetarie. Obiettivo principale di questo lavoro è valutare l’impatto dei vantaggi in termini di componenti di reddito non monetarie (imputed rent), di cui godono le famiglie che abitano in una casa di proprietà per il fatto che non sono tenute a pagarne l’affitto. In particolare, si …

MISURARE LE DISUGUAGLIANZE SOCIO-ECONOMICHE NELLE MALATTIE CRONICHE IN RELAZIONE ALLO STILE DI VITA

2017

In Europa, le principali malattie non trasmissibili (MNT), comprendono il diabete, le malattie cardiovascolari, il cancro, le malattie respiratorie croniche e i disturbi mentali, e rappresentano complessivamente circa l'86% delle morti e il 77% della spesa sanitaria. Delle sei regioni dell'OMS, la regione europea è quella più colpita dalle MNT (WHO, 2014). È stato dimostrato che almeno l'80% di tutte le malattie cardiache, ictus e diabete di tipo 2 e almeno un terzo dei casi di cancro sono evitabili (WHO, 2013). La strategia di sorveglianza globale di OMS sulle MNT si basa su una visione multidimensionale di determinanti della malattia in cui i fattori di rischio sono raggruppati lungo la t…

Study of tin and gold halos in the medieval wall painting depicting Saints Luke the Evangelist and Gregory the Great in Palermo’s San Francesco d’Ass…

2022

Lo scopo di questo studio è quello di fornire un supporto al restauratore quando si trova ad affrontare un manufatto con doratura a foglia di stagno. Lo studio dei materiali originali ha fornito un quadro completo dei vari componenti coinvolti, organici e inorganici, e sono stati delineati i degradi più comuni, nonché i metodi di conservazione per questi materiali estremamente fragili e sensibili come le foglie metalliche The purpose of this study is to provide a support for the restorer when facing an artifact with tin leaf gilding. The study of the original materials gave a complete picture of the various components involved, organic and inorganic, and the most common degradations were ou…

The role of Dutch in the development of East Anglian English

2013

Dutch speakers may or may not have contributed a certain amount of lexical material to modern East Anglian dialects. There is a much stronger case to be made, however, for arguing that Dutch speakers did have a rather profound infl uence on the morphology of East Anglian English, dating from the time when almost forty percent of the population of the capital of East Anglia, Norwich, were refugees from the Low Countries. That infl uence was indirect, and mediated through mechanisms of linguistic change associated with language contact.

Locust neuropeptides stimulating sex pheromone production in female European corn borer moth, Ostrinia nubilalis

1990

Abstract The presence of a pheromonotropically active hormone (PBAN-like substance) from locust organs, ( Locusta migratoria ) has been demonstrated. Extracts of brain, corpora cardiaca, corpora allata, suboesophageal ganglia and thoracic ganglia of L. migratoria caused highly pheromonotropic responses in decapitated females of the European corn borer moth ( Ostrinia nubilalis ). The highest activity per unit weight of tissue was found in the corpora cardiaca and corpora allata of the locust followed by the brain plus suboesophageal ganglion of O. nubilalis . Following 8 days of disconnection, separating the corpora allata from the corpora cardiaca and suboesophageal ganglion, the pheromono…

Expression of neurotrophins, GDNF, and their receptors in rat thyroid tissue

1999

Levels of mRNA for neurotrophins (brain-derived neurotrophic factor, BDNF; neurotrophin 3, NT-3; neurotrophin 4, NT-4) and their receptors (trkA, trkB, trkC) and for glial cell line-derived neurotrophic factor (GDNF) and its receptors (ret, GDNFR-alpha) were measured in rat thyroid tissue by ribonuclease protection assays. In thyroid tissue the NT-3 mRNA level was threefold lower and the NT-4 mRNA level sixfold higher than those detected in adult rat hippocampus, while BDNF mRNA was undetectable. Very low levels of mRNA for truncated trkB and trkC receptors and no catalytic trkA, trkB or trkC were found. In conclusion NT-3 and NT-4, but not the corresponding functional receptors, are expres…

Transgenic overexpression of corticotropin releasing hormone provides partial protection against neurodegeneration in an in vivo model of acute excit…

2008

Abstract Corticotropin releasing hormone (CRH) is the central modulator of the mammalian hypothalamic–pituitary–adrenal (HPA) axis. In addition, CRH affects other processes in the brain including learning, memory, and synaptic plasticity. Moreover, CRH has been shown to play a role in nerve cell survival under apoptotic conditions and to serve as an endogenous neuroprotectant in vitro . Employing mice overexpressing murine CRH in the CNS, we observed a differential response of CRH-overexpressing mice (CRH-COE hom -Nes) to acute excitotoxic stress induced by kainate compared with controls (CRH-COE con -Nes). Interestingly, CRH-overexpression reduced the duration of epileptic seizures and pre…

2013

Following traumatic brain injury (TBI) neuroinflammatory processes promote neuronal cell loss. Alpha-melanocyte-stimulating hormone (α-MSH) is a neuropeptide with immunomodulatory properties, which may offer neuroprotection. Due to short half-life and pigmentary side-effects of α-MSH, the C-terminal tripeptide α-MSH(11–13) may be an anti-inflammatory alternative. The present study investigated the mRNA concentrations of the precursor hormone proopiomelanocortin (POMC) and of melanocortin receptors 1 and 4 (MC1R/MC4R) in naive mice and 15 min, 6, 12, 24, and 48 h after controlled cortical impact (CCI). Regulation of POMC and MC4R expression did not change after trauma, while MC1R levels incr…