Search results for "Government"
showing 10 items of 1098 documents
Modulation of P-Glycoprotein-Mediated Multidrug Resistance by Synthetic and Phytochemical Small Molecules, Monoclonal Antibodies, and Therapeutic Nuc…
2014
Multidrug resistance of malignant tumors severely hampers their successful treatment frequently leading to fatal consequences for affected patients. During the past three decades, many efforts have been spent to develop strategies to overcome multidrug resistance. Many chemical compounds have been shown to inhibit the drug efflux of the multidrug-resistance-mediating P-glycoprotein. Chemical P-glycoprotein inhibitors are from the classes of calcium channel antagonists, calmodulin inhibitors, cyclosporins, antiarrhythmics, hormones, antimalarials, antibiotics, detergents, beta-blockers, antidepressants, blood pressure lowering indol alkaloids, aerobic glycolysis inhibitors, HIV-protease inhi…
Foreign Direct Investment in oil-abundant countries: The role of institutions
2019
The present work reassesses the impact of good governance and democracy on Foreign Direct Investment (FDI) in oil-abundant countries. To this end, we estimate the effect of host countries’ institutions on greenfield FDI, using a gravity equation for a dataset that covers 182 countries during 2003-2012. Our findings confirm that compliance to rule of law, lack of corruption, political stability and democracy could boost new FDI links through the extensive margin. Our results could not rule out the “oil curse”, meaning that oil producers attract fewer new greenfield projects than similar countries without oil. Unlike other studies, we show that the impact of institutions is not necessarily un…
Antisense lipoprotein[a] therapy: State-of-the-art and future perspectives
2020
Several lines of evidence now attest that lipoprotein[a] (Lp[a]) is a significant risk factor for many cardiovascular disorders. This enigmatic lipoprotein, composed of a single copy of apolipoprotein B (apoB) and apolipoprotein[a] (apo [a]), expresses peculiar metabolism, virtually independent from lifestyle interventions. Several therapeutic options have hence been proposed for lowering elevated Lp[a] values, with or without concomitant effect on low density lipoprotein (LDL) particles, mostly encompassing statins, ezetimibe, nicotinic acid, lipoprotein apheresis, and anti-PCSK9 monoclonal antibodies. Since all these medical treatments have some technical and clinical drawbacks, a novel s…
The first colonization of Ibiza and Formentera (Balearic Islands, Spain): Some more islands out of the stream?
1995
Abstract The Balearic Islands, off the east coast of Spain, have provided a focus of interest in investigations of the earliest colonization of the Mediterranean islands, because of the relatively late date of their oldest sites. Mallorca was visited in the fifth millennium BC and inhabited by the third, and Menorca was colonized during the closing centuries of the third millennium; this therefore makes Ibiza and Formentera special cases of isolation, since they were evidently not occupied until about 2000 BC and moreover were essentially deserted between roughly the thirteenth and seventh centuries BC. The paper presents all the currently available data relevant to this question, particula…
Julien : les années parisiennes
2009
This article intends to scrutinize in what ways Julian’s stay in Gaul as a Caesar were decisive in Julian’s political and military education, and whether a specific ruling style and manner may be detected in the Parisian years of Julian’s government. Relying on a critical analysis of the documentation (Julian himself, Mamertinus, Ammianus, Libanios), the author examines the military and civilian aspects of Julian’s training as an apparently inexperienced ruler but quick learner. She carries out a prosopographical study of the Caesar’s circle and the administrative staff which was then on duty, combining friendly and hostile persons. Gaul offered him a training ground and he became even the …
Territorialization in Political Discourse: A Pragma-Linguistic Study of Jerzy Buzek’s Inaugural Speeches
2011
The purpose of this study is to review some discursive strategies used to (de)territorialize the European public sphere by the newly elected President of the European Parliament Jerzy Buzek. A corpus of his inaugural speeches (over 7,000 words) is examined in order to identify salient pragma-linguistic devices, such as for example high-frequency references, linguistic markers of identities, values and interests, as well as metaphors and argumentative schemata. These are presumed to have been used by Buzek to territorialize the presidential office: to position himself as its leader, to establish his credibility, to become its agenda-setter. Additionally, the analysis focuses on the way Buzek…
Zvaigžņotā Debess: 2009, Rudens (205)
2009
Contents: I.Daube. Jānis Ikaunieks ; A.Balklavs. Mountains on the Venus ; TASS and “Pravda” materials. Soviet Automatic Stations “Venera-5” and “Venera-6” Reach Venus ; A.Alksnis. Gathering of Astronomers at the University ; A.Alksnis, M.Ābele, I.Eglītis, B.Rjabovs, K.Salmiņš, I.Pundure. Directions of Scientific Research of the UL Institute of Astronomy Assessed ; D.Docenko. Meteorite Fallen in Sudan Recovered ; A.Alksnis. How Asteroids Will Disturb Observation with Extremely Large Telescopes ; M.Gills. Daily in Network with Astronomy ; I.Pundure. Arturs Balklavs and Astronomy of Latvia (continued) ; M.Sudārs. IXV – Step towards Reusable Space Vehicles ; V.Kalniņš. Hyperdrive and Heim’s Qua…
Students Mobility: Assessing the Determinants of Attractiveness Across Competing Territorial Areas
2016
A central question for education authorities has become ‘‘which factors make a territory attractive for tertiary students?’’ Tertiary education is recognised as one of the most important assets for the development of a territory, thus students’ mobility becomes a brain drain issue whenever there are prevalent areas that attract students from other territories. In this paper, we try to identify the most important factors that could affect student mobility in Italy. In doing that we analyse students’ flows across competing territorial areas which supply tertiary education programs. We will consider a wide range of determinants related to the socio-economic characteristics of the areas as well…
Helianthemum scopulicolum (Cistaceae), a new species from Majorca (Balearic Islands, Spain)
1999
Rupicolous plants coming from a single Balearic locality are described as a new species, Helianthemum scopulicolum. The plant is diploid (2n=20) and belongs to Helianthemum subgenus Helianthemum sect. Helianthemum. On morphological grounds, Helianthemum scopulicolum is related to some members of the H. apenninum aggregate, notably H. apenninum s.l., H. asperum and H. violaceum. However, the new species can be distinguished on the basis of leaves green, shining, glabrescent on the adaxial surface, deciduous short bracts, glabrescent inner sepals lacking long setae and pink-purple flowers.
Euphorbia Nurae P. Fraga & Rosselló (Euphorbiaceae), a New Species from Minorca (Balearic Islands)
2011
Abstract FRAGA-ARGUIMBAU, P. & J. A. ROSSELLO (2011). Euphorbia nurae P. Fraga & Rossello (Euphorbiaceae), a new species from Minorca (Balearic Islands). Candollea 66: 181–190. In English, English and French abstracts. Euphorbia nurae P. Fraga & Rossello (Euphorbiaceae sect. Cymatospermum (Prokh.) Prokh.) is described as a new species from coastal sites of Minorca (Balearic Islands). Morphological features suggest that Euphorbia exigua L., Euphorbia dracunculoides Lam. and Euphorbia sulcata Loisel. are the most closely related taxa, but the new species can be easily discriminated by several morphological characters.