Search results for "Gradation"
showing 10 items of 1275 documents
Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease…
2009
Alcadeins (Alcs) constitute a family of neuronal type I membrane proteins, designated Alc(alpha), Alc(beta), and Alc(gamma). The Alcs express in neurons dominantly and largely colocalize with the Alzheimer amyloid precursor protein (APP) in the brain. Alcs and APP show an identical function as a cargo receptor of kinesin-1. Moreover, proteolytic processing of Alc proteins appears highly similar to that of APP. We found that APP alpha-secretases ADAM 10 and ADAM 17 primarily cleave Alc proteins and trigger the subsequent secondary intramembranous cleavage of Alc C-terminal fragments by a presenilin-dependent gamma-secretase complex, thereby generating "APP p3-like" and non-aggregative Alc pe…
Electrochemical characterization of mangrove sediments: A proposal of new proxies for organic matter oxidation
2019
Abstract The voltammetric response of microparticulate deposits resulting from solvent evaporation of ethanolic extracts of mangrove sediments in contact with aqueous acetate buffer is hereby described. Dated sediment cores sampled from the Peruvian mangrove system (“Manglares de Tumbes” National Sanctuary) presented voltammetric responses dominated by oxidative signals of organic components that exhibit significant variations depending on the depth. Voltammetric data allowed for the definition of electrochemical indexes representative of the electrochemically oxidable organic matter fraction. These electrochemical indexes were fEAOM (for the total amount of organic matter being electrochem…
Fast field cycling NMR relaxometry as a tool to monitor Parmigiano Reggiano cheese ripening.
2020
Abstract It is widely recognized that the longer the ageing, the more valuable Parmigiano Reggiano (PR) cheese becomes, due to the improvement of its sensorial and nutritional properties. Up to now, the evaluation of PR properties has been performed on samples mainly aged up to 40 months. For this reason, this study was aimed at collecting information about the chemical-physical characteristics of PR cheeses after ageing at 24, 48 and 84 months. The basic analyses on water amount, protein content and volatile organic compounds (VOC) revealed that PR ageing is associated to the decomposition of the organic components into smaller units. This drives water molecules closer to the aforementione…
Model of ageing inception and growth from microvoids in polyethylene-based materials under AC voltage
2008
Several degradation mechanisms may affect polymeric insulation system reliability. Some authors postulate that, even in a perfect dielectric, nanoscale cavities can enlarge due to various mechanisms (from mechanical fatigue to lowering of the degradation reaction energy barrier) up to a point where highly energetic phenomena, which bring about breakdown, can be incepted. Other authors are more focused on the inherent limits of manufacturing processes, which leave cavities within the insulation system whose size is large enough to cause electron avalanches, thus a measurable partial discharge (PD) activity, from the time the system is put in service or as a function of external factors (e.g.…
Enhancement of biomass retention in an EGSB reactor used to treat 1-methoxy-2-propanol
2017
An evaluation of a model ecosystem with DDT
1980
The reproducibility, variability, and reliability of a simple aquatic-terrtestrial model ecosystem experiment was tested with p,p'-DDT. The variation among the model replicates as well as within the units was studied by using hierarchal analysis of variance. the complete budget of the chemical was calculated and a theoretical transport model was constructed. The degradation and accumulation of DDT was followed by gas chromatographic residue analysis, which showed good reproducibility of the experimental design. The degradation of DDT in the model was similar to that found in the field, but the determination of concentration factors was questionable. The material balance tables revealed that…
Oilseed treatment by ultrasounds and microwaves to improve oil yield and quality: An overview.
2016
International audience; Efficiency is a key point to ensure the profitability in the production of vegetable oils from oilseeds. To maximize the recovery yields of seed oils, the traditional process involves mechanical expression followed by subsequent chemical extraction using organic solvents (e.g. hexane). Besides health, environmental, and economic related issues to the use of organic solvents, thermal treatment of seeds during conventional oil extraction process inevitably leads to chemical changes (e.g. changes in macronutrients such as protein denaturation/degradation in the meal, oil oxidation, and changes in minor constituents such as fatty acids, sterols, phenolic compounds and to…
Soil erosion modelling: a global review and statistical analysis
2021
40 Pags.- 10 Figs.- 2 Tabls.- Suppl. Informat. The definitive version is available at: https://www.sciencedirect.com/science/journal/00489697
Assessing land condition as a first step to achieving land degradation neutrality : A case study of the Republic of Srpska
2018
Abstract Land Degradation Neutrality (LDN) is a key voluntary and aspirational target of Sustainable Development Goal (SDG) 15 which urges countries to protect, restore and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat desertification, and halt and reverse land degradation and halt biodiversity loss. A first and critical important step in the implementation of LDN is assessing the current land condition using not only active restoration of degraded land, but also targeting land degradation drivers behind the land degradation process. In a first step to achieve these goals, countries were provided a global dataset for three sub-indicators of land degra…
Random Lasing of Rhodamine 6G Solution Containing TiO2:Silica Core:Shell Nanoparticles
2012
High efficiency and low rate of photodegradation was obtained in a random laser suspending TiO2@Silica nanoparticles in ethanol solution of Rhodamine 6G. The TiO2 nanoparticles were coated with a silica shell prepared via Stober method.