Search results for "Guide"
showing 10 items of 1478 documents
La sentencia y su ejecución en el proyecto dominicano de ley sobre control judicial de la administración pública
2021
The regime of the execution of the sentence is analyzed, starting from the powers of declarative and executive substitution of the contentious-administrative judge. It begins with the reference to the constitutional guidelines of the administrative process. Then, the different modalities of judicial substitution are described in the types of sentences (declarative, constitutive and conviction) regulated in the project, to then refer to the regime of executive seizure of public goods. It ends by describing: the powers granted to the judge to agree indirect measures that assist with the execution of the judgment, the cases of impossibility of execution and the extension of the sentence to thi…
Perspectives for the Treatment of Brucellosis in the 21st Century: The Ioannina Recommendations
2007
Policy Forum. Competing interests: ER has received research grants from Daiichi, Bayer, and Theravance and has served as a consultant to Pfizer, Theravance, Bayer, Wyeth, Rosetta, and BiondVax. Summary Points Brucellosis remains the commonest anthropozoonosis worldwide, and its treatment remains complex, requiring protracted administration of more than one antibiotic. In November 2006, a consensus meeting aimed at reaching a common specialist statement on the treatment of brucellosis was held in Ioannina, Greece under the auspices of the International Society of Chemotherapy and the Institute of Continuing Medical Education of Ioannina. The author panel suggests that the optimal treatment o…
Report of the Scientific Committee of the Spanish Agency for Food Safety and Nutrition (AESAN) on the review and update of Dietary Recommendations fo…
2020
*This record is given in both English and Spanish Until now, the established dietary patterns have not demonstrated to achieve the goal of maintaining good health in the general population. In addition to the human health, the current dietary models, called “Sustainable Healthy Diets”, take into account the concept of sustainability in all its aspects. With this goal in mind the World Health Organization (WHO) and the Food and Agriculture Organization of the United Nations (FAO) encourage the development of national food-based dietary recommendations within the specific context of the Sustainable Healthy Diets, taking into account the social, cultural, economic, ecological and environmental…
Intraoperative transfusion practices in Europe
2016
PubMed: 26787795
Development of a GC–MS/MS strategy to determine 15 mycotoxins and metabolites in human urine
2014
The widespread mycotoxins contamination of food commodities has made the monitoring of their levels essential. To overcome the disadvantages of the indirect approach by food analysis, detection of mycotoxin as biomarkers in urine provides a useful and specific data for exposure assessment to these food contaminants. In this work, a sensitive, rapid and accurate method based on gas chromatography-tandem mass spectrometry procedure to determine 15 mycotoxins and metabolites in human urine was optimized and validated taking into consideration the guidelines specified in Commission Decision 2002/657/EC and 401/2006/EC. A salting-out assisted acetonitrile-based extraction was used for sample pre…
Global-Local model for guided wave scattering problems with application to defect characterization in built-up composite structures
2020
Abstract Predicting scattering of elastic guided waves in multi-layered solid plates with geometrical and/or material discontinuities is of great interest to many fields, including ultrasonic-based Non-Destructive Testing (NDT) and health monitoring of critical structural components (SHM). The problem is complicated by the multimode and dispersive behaviour of the guided waves. This paper describes a unified Global-Local (GL) approach that is computationally efficient in cases that can be very complex in terms of geometry and/or material properties. One example of this is a composite built-up structure. The proposed GL procedure discretizes the “local” region with the scattering discontinui…
The impact of the EMA change in definition of "dose" on the BCS dose-solubility ratio: a review of the biowaiver monographs.
2013
The Biopharmaceutics Classification System (BCS) defines the solubility characteristics of an active pharmaceutical substance based on its dose-solubility ratio: for highly soluble drugs this ratio is less than 250 mL over a defined pH range. Prior to the revision of the European Medicines Agency (EMA, formerly EMEA) guideline in 2010, the "dose" in this ratio was consistently defined by the US FDA, the EMA, and the WHO biowaiver guidelines as the highest dosage strength. However, in the revised EMA guideline, the dose is defined as the highest single dose administered according to the Summary of Product Characteristics. The new EMA criterion for highly soluble may be closer to the actual c…
The importance of moral sensitivity when including persons with dementia in qualitative research
2012
Author's version of an article in the journal: Nursing Ethics. Also avaliable from the publisher at: httjp://dx.doi.org/10.1177/0969733012455564 The aim of the article is to show the importance of moral sensitivity when including persons with dementia in research. The article presents and discusses ethical challenges encountered when a total of fifteen persons with dementia from two nursing homes and seven proxies were included in a qualitative study. The examples show that ethical challenges may be unpredictable. As researcher you participate with the informants in their daily life and in the interview situation, and it is not possible to plan all that may happen. A procedural proposal to …
Acute cholecystitis during COVID-19 pandemic: a multisocietary position statement
2020
AbstractFollowing the spread of the infection from the new SARS-CoV2 coronavirus in March 2020, several surgical societies have released their recommendations to manage the implications of the COVID-19 pandemic for the daily clinical practice. The recommendations on emergency surgery have fueled a debate among surgeons on an international level.We maintain that laparoscopic cholecystectomy remains the treatment of choice for acute cholecystitis, even in the COVID-19 era. Moreover, since laparoscopic cholecystectomy is not more likely to spread the COVID-19 infection than open cholecystectomy, it must be organized in such a way as to be carried out safely even in the present situation, to gu…
Management of acute promyelocytic leukemia: updated recommendations from an expert panel of the European LeukemiaNet
2019
Abstract Since the comprehensive recommendations for the management of acute promyelocytic leukemia (APL) reported in 2009, several studies have provided important insights, particularly regarding the role of arsenic trioxide (ATO) in frontline therapy. Ten years later, a European LeukemiaNet expert panel has reviewed the recent advances in the management of APL in both frontline and relapse settings in order to develop updated evidence- and expert opinion–based recommendations on the management of this disease. Together with providing current indications on genetic diagnosis, modern risk-adapted frontline therapy, and salvage treatment, the review contains specific recommendations for the …