Search results for "Guidelines."

showing 10 items of 611 documents

Blood Transfusion Management for Patients Treated With Anti-CD38 Monoclonal Antibodies

2018

Daratumumab has proven to be highly efficacious for relapsed and refractory multiple myeloma (MM) and has recently been approved in the frontline setting for MM patients ineligible for transplantation. In the future, expanded indications are possible for daratumumab and other anti-CD38 monoclonal antibodies in development. For several years, it has been recognized that these therapies interfere with blood bank testing by binding to CD38 on red blood cells and causing panagglutination on the Indirect Antiglobulin Test. This can lead to redundant testing and significant delays in patient care. Given the anticipated increase in utilization of anti-CD38 monoclonal antibodies, as well as the tra…

lcsh:Immunologic diseases. Allergymedicine.medical_specialtyErythrocytesBlood transfusionmedicine.drug_classmedicine.medical_treatmentImmunologyAntineoplastic AgentsReview030204 cardiovascular system & hematologyCD38Monoclonal antibody03 medical and health sciences0302 clinical medicinemedicineHumansImmunology and AllergyBlood TransfusionDiagnostic ErrorsIntensive care medicinetransfusionIsatuximabbusiness.industryAntibodies MonoclonalDaratumumabdaratumumabADP-ribosyl Cyclase 1TransplantationCoombs TestBlood Grouping and Crossmatchingmonoclonal antibodyPractice Guidelines as TopicIndirect Antiglobulin Testlcsh:RC581-607Multiple MyelomabusinessCD38Blood bankProtein Bindingisatuximab030215 immunologyFrontiers in Immunology
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Improving quality and safety in nursing homes and home care: the study protocol of a mixed-methods research design to implement a leadership interven…

2018

IntroductionNursing homes and home care face challenges across different countries as people are living longer, often with chronic conditions. There is a lack of knowledge regarding implementation and impact of quality and safety interventions as most research evidence so far is generated in hospitals. Additionally, there is a lack of effective leadership tools for quality and safety improvement work in this context.Methods and analysisThe aim of the ‘Improving Quality and Safety in Primary Care—Implementing a Leadership Intervention in Nursing Homes and Homecare’ (SAFE-LEAD) study is to develop and evaluate a research-based leadership guide for managers to increase quality and safety compe…

leadershipAttitude of Health PersonneleducationPsychological interventionGuidelines as TopicNorwegiannursing homescontextprimary care03 medical and health sciencesPatient safety0302 clinical medicineNursingSurveys and QuestionnairesProtocolpatient safetyHumansMedicineSocial media15061704030212 general & internal medicineCompetence (human resources)interventionNetherlandspasientsikkerhetNorway:Medical disciplines: 700::Clinical medical disciplines: 750::Geriatrics: 778 [VDP]business.industry030503 health policy & servicesMultimethodologyaldershjemGeneral MedicineHome Care ServicesQuality Improvementlanguage.human_languageNursing HomesPeer reviewsykehjemResearch DesignqualitylanguageHealth Services Research0305 other medical scienceNursing homesbusinessProgram EvaluationBMJ Open
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Creating a Framework for Improving the Learnability of a Complex System

2006

When designing complex systems, it is crucial but challenging to make them easy to learn. In this paper, a framework for improving the learnability of a complex system is presented. A classification of factors affecting the learnability of a building modeling system as well as guidelines that refine the factors into practical ways of action are introduced. The factors and guidelines include issues related to the user interface, conformity of the system to user’s expectations, and training. The classification is based on empirical research during which learnability was assessed with several methods. The methodology and the classification of learnability factors can be used as references when…

learnabilityease-of-learningguidelinescomplex systemsgrounded theory
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Autophagy

2021

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide…

macroautophagy;autophagyAutophagosome[SDV]Life Sciences [q-bio]canceLC3 macroautophagyautophagosomeneurodegeneration;[SDV.BC]Life Sciences [q-bio]/Cellular BiologyAutophagy AutophagosomeNOstress vacuolestressautophagic processesstrerfluxLC3cancerguidelinesAutophagosome; cancer; flux; LC3; lysosome; macroautophagy; neurodegeneration; phagophore; stress; vacuoleSettore BIO/06 - Anatomia Comparata E Citologia[SDV.BC] Life Sciences [q-bio]/Cellular BiologyComputingMilieux_MISCELLANEOUSMedaka oryzias latipesphagophorevacuoleQHneurodegenerationAutophagosome cancer flux LC3 lysosome macroautophagy neurodegeneration phagophore stress vacuoleautophagy; autophagic processes; guidelines; autophagosome; cancer; flux; LC3; lysosome; macroautophagy; neurodegeneration; phagophore; stress; vacuolefluxmacroautophagystress.lysosomeAutophagosome; LC3; cancer; flux; lysosome; macroautophagy; neurodegeneration; phagophore; stress; vacuoleSettore BIO/17 - ISTOLOGIARC
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Robotic i.v. medication compounding: Recommendations from the international community of APOTECAchemo users.

2016

Purpose The development of recommendations for advancing automated i.v. medication compounding is described. Summary Managing the shift from manual to robotic compounding of i.v. therapies requires an awareness of how automation affects practice and how to best implement robotics into current practice. An international panel of pharmacy professionals, researchers, and technology leaders with experience in i.v. robotics collaborated during a two-day meeting in August 2014 to define a general set of principles to broaden the understanding of the fundamental elements of robotic compounding worldwide. Participants were divided into four working groups (technology and safety; drugs and products;…

media_common.quotation_subjectDrug CompoundingPharmacy030226 pharmacology & pharmacy03 medical and health sciencesAutomation0302 clinical medicineNursingSurveys and QuestionnairesMedicineHumansQuality (business)Set (psychology)media_commonPharmacologyDrug compoundingMedical educationbusiness.industryHealth PolicyInternational communityRoboticsCompoundingCurrent practice030220 oncology & carcinogenesisPractice Guidelines as TopicAdministration IntravenousWorking groupbusinessPharmacy Service HospitalAmerican journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
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Promoting good practice in health promotion in Spain: the potential role of a new agency.

2016

AbstractHealth promotion (HP) activities should be evaluated both in terms of process and results. However there remains a lack of information regarding the types of HP community interventions that are performed in our country, which of these are based on the best available evidence, and how the evidence available can be translated into HP recommendations for action? Spain does not have a dedicated body to answer such questions. If one existed, its role should be to identify the full range of interventions available to promote health, evaluate them and, in cases where there are positive results, facilitate their transfer and implementation. The aim of this article is to reflect on the need …

media_common.quotation_subjectPsychological interventionContext (language use)Health PromotionScientific evidence03 medical and health sciences0302 clinical medicineGovernment AgenciesExcellenceAgency (sociology)MedicineEvidenciaHumans030212 general & internal medicinemedia_commonEvidenceContextualizationbusiness.industry030503 health policy & servicesPromoción de la saludPublic Health Environmental and Occupational HealthPublic relationsCommunity interventionHealth promotionSpainPractice Guidelines as TopicIntervención en la comunidad0305 other medical sciencebusinessStrengths and weaknessesGaceta sanitaria
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Evaluation tools for spiritual support in end of life care: increasing evidence for their clinical application.

2015

Purpose of review To summarize current evidence on evaluation tools for spiritual care, paying special attention to recent validations and new instruments, systematic reviews, recent consensus on spiritual care and its measurement, plus other emergent topics. Recent findings The systematic review resulted in 45 identified studies, 14 of which were considered: five works addressed the need for development and validation of spiritual tools; three studies reviewed tools for spirituality assessment, interventions, or related concepts; three more covered the efforts to define guidelines and priorities for spiritual care and its measurement. Other topics such as pediatric spiritual care, the use …

media_common.quotation_subjectPsychological interventionCritical Care and Intensive Care MedicineBioinformaticsPediatricsQuality of life (healthcare)medicineHumansFamilySpiritualityCultural Competencymedia_commonMedical educationTerminal CareOncology (nursing)Data CollectionGeneral Medicinemedicine.diseaseComplicated griefSystematic reviewOncologyCaregiversResearch DesignPractice Guidelines as TopicQuality of LifeGriefSpiritual careGriefPsychologyEnd-of-life careCultural competenceCurrent opinion in supportive and palliative care
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Multimodality imaging strategies for the assessment of aortic stenosis: Viewpoint of the heart valve clinic international database (HAVEC) group

2016

International audience; Aortic stenosis is the most frequent valvular heart disease. In aortic stenosis, therapeutic decision essentially depends on symptomatic status, stenosis severity, and status of left ventricular systolic function. Surgical aortic valve replacement or transcatheter aortic valve implantation is the sole effective therapy in symptomatic patients with severe aortic stenosis, whereas the management of asymptomatic patients remains controversial and is mainly based on individual risk stratification. Imaging is fundamental for the initial diagnostic work-up, follow-up, and selection of the optimal timing and type of intervention. The present review provides specific recomme…

medicine.medical_specialty030204 cardiovascular system & hematologyDoppler echocardiographyAsymptomaticMultimodal ImagingRisk Assessment03 medical and health sciences0302 clinical medicineAortic valve replacementInternal medicinemedicineHumansRadiology Nuclear Medicine and imaging030212 general & internal medicineHeart valvehumanaortic valve stenosis ◼ biomarkers ◼ echocardiography Doppler ◼ guideline ◼ prognosis ◼ standardsalgorithmmedicine.diagnostic_testbusiness.industrypractice guidelinevalvular heart diseaseAortic Valve Stenosismedicine.diseasebiological markerPrognosis3. Good healthStenosismedicine.anatomical_structureclassificationAortic valve stenosisPractice Guidelines as TopicCardiologycardiovascular system[SDV.IB]Life Sciences [q-bio]/BioengineeringRadiologymedicine.symptomCardiology and Cardiovascular MedicineRisk assessmentbusinessAlgorithmsBiomarkers
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Providing pediatric well-care and sick visits in the COVID-19 pandemic era: the recommendations of the Italian pediatric society.

2020

AbstractPediatricians have observed a significant decrease in in-person child health visits during the COVID-19 pandemic. In the post lockdown period, the coronavirus trend remains positive in Italy but fears of a second wave have recently grown in Italy due to active hotbeds of contagion. The pandemic may negatively affect the care of pediatric patients and overall children welfare as it may present with severe signs and symptoms or it may complicate. The Italian Pediatric Society recommend to separate well visits from sick ones, to educate families and to promote hygienic strategies to provide an adequate pediatric assistance in case of a second pandemic wave.

medicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)COVID19Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)media_common.quotation_subjectPneumonia ViralChild WelfareSigns and symptomsPediatricsChild healthBetacoronavirusPandemicmedicineDisease Transmission InfectiousHumansVisitChildChildrenPandemicsSocieties Medicalmedia_commonMaternal and child healthbusiness.industrySARS-CoV-2lcsh:RJ1-570COVID-19lcsh:PediatricsSettore MED/38ItalyFamily medicinePractice Guidelines as TopicCommentarybusinessCoronavirus InfectionsWelfareItalian journal of pediatrics
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Analysis and review of the perioperative management of COVID-19 patients in thoracic surgery.

2021

Resumen Debido a la grave situacion de pandemia que vivimos causada por el COVID-19, la Seccion de Anestesia Cardiaca, Vascular y Toracica de la SEDAR pretende dar informacion de los aspectos mas relevantes a considerar en pacientes con sospecha o infeccion confirmada por coronavirus que van a ser sometidos a cirugia toracica. Creemos que es esencial mantener una optima transmision de informacion para llevar a cabo maniobras seguras, tanto para los pacientes como para el personal sanitario. La estrategia de manejo debe basarse en una organizacion exquisita del trabajo, definiendo quien, como y cuando va a realizar cada tarea y procedimiento. Las recomendaciones que se proponen, tras valorar…

medicine.medical_specialty2019-20 coronavirus outbreakThoracic Surgical Procedureone-lung ventilationCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MEDLINEcirugía torácica030204 cardiovascular system & hematologyCritical Care and Intensive Care MedicineArticlePerioperative Care03 medical and health sciencesmanejo de vía aérea0302 clinical medicinelung isolation/separationBronchoscopyIntubation Intratrachealventilation unipulmonarMedicineHumansAnesthesiaairway managementPerioperative managementCirurgiaLaryngoscopybusiness.industryGeneral surgeryAnestèsiaaislamiento/separación pulmonarCOVID-19General MedicineLetter to the DirectorThoracic Surgical Proceduresthoracic surgeryAnesthesiology and Pain Medicine030228 respiratory systemCardiothoracic surgeryPerioperative carePractice Guidelines as TopicAirway ExtubationbusinessHumanitiesRevista espanola de anestesiologia y reanimacion
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