Search results for "H-2"

CCDC 1545350: Experimental Crystal Structure Determination

2017

Related Article: Rajendhraprasad Tatikonda, Evgeny Bulatov, Elina Kalenius, Matti Haukka|2017|Cryst.Growth Des.|17|5918|doi:10.1021/acs.cgd.7b01034

Ses racines et son développement de 1820 à 1920

2017

The aim of the study is to examine the Saami book history in the context of Finland in order to understand its evolution from 1820 to 1920. The study focuses on books and other printed materials in Saami language(s) (or idioms) and it looks into archival documents to throw light on their intellectual history. The Saami book history has unfolded slowly, and occasionally, it has appeared to fall into decline. The present study follows the French school of book history that uses multidisciplinary methods to examine books as a reflection of ideology in the context of a given culture at a given time. Such an approach allows us to see how a minority can express itself, what possibilities there ar…

D1 receptors play a major role in the dopamine modulation of mouse ileum contractility

2010

Since the role of dopamine in the bowel motility is far from being clear, our aim was to analyse pharmacologically the effects of dopamine on mouse ileum contractility. Contractile activity of mouse ileum was examined in vitro as changes in isometric tension. Dopamine caused a concentration-dependent reduction of the spontaneous contraction amplitude of ileal muscle up to their complete disappearance. SCH-23390, D1 receptor antagonist, which per se increased basal tone and amplitude of spontaneous contractions, antagonized the responses to dopamine, whilst sulpiride or domperidone, D2 receptor antagonists, were without effects. The application of both D1 and D2 antagonists had additive effe…

Response to dopamine agonists of the rat isolated uterus.

1993

1. Quinpirole did not produce any effect in isolated uterus from oestrogenized rats even when it is contracted by KCl (37 mM). 2. Fenoldopam produced a relaxant effect on rat isolated uterus contracted by KCl which was not significantly modified by SCH 23390. 3. Reserpine decreased the effect of the lowest doses of fenoldopam. In reserpinized rats, propranolol (10(-9), 10(-8), 10(-7) M) antagonized the effect of the lowest doses of fenoldopam and neither SCH 23390, sulpiride nor ranitidine modified the effect of fenoldopam. 4. The results confirm our previous finding that DA1-receptors are not functional in our preparation. The effect of fenoldopam was partially due to a catecholamine-relea…

D2-dopamine receptor blockade modulates temporal resolution in goldfish.

2002

A possible effect of dopamine on the temporal resolution of goldfish was investigated in a behavioral, two-alternative, forced-choice procedure. Flicker fusion frequency (FFF) was measured before and after bilateral intravitreal injections of D1- or D2-dopamine receptor (D1-/D2-R) antagonists, or after depletion of retinal dopamine by bilateral intravitreal injections of the dopaminergic neurotoxin 6-hydroxydopamine (6-OHDA). Prior to drug injections, fish achieved FFFs of 33–39 Hz. A D1-R antagonist, SCH 23390, reduced FFF by about 12% (P > 0.1), whereas a D2 antagonist, sulpiride, reduced the relative FFF by 25% (P < 0.03). Depletion of retinal dopamine with 6-OHDA induced a gradual…

Major histocompatibility complex regulation of cytokine production.

1996

This review describes the phenomenon of the major histocompatibility complex (MHC) control of cytokine production both in experimental animals and in humans. H-2 (mouse MHC) regulates which type of cytokine is selectively produced in response to the hapten trinitrophenyl (TNP). T cells from TNP-immune H-2k mice produce interferon-gamma (IFN-gamma), interleukin-2 (IL-2), IL-3, IL-5, tumor necrosis factor-alpha (TNF-alpha), IL-10, and very low levels of IL-4 on reexposure to the specific antigen in vitro. By contrast, T cells from H-2d mice produce IL-3, TNF-alpha, IL-10, and IL-4 but very low levels of IL-2, IL-5 and IFN-gamma. As MHC-congenic matched strains (BALB/k and BALB/c) are used, th…

H2-M polymorphism in mice susceptible to collagen-induced arthritis involves the peptide binding groove.

1996

The ability to develop type II collagen (CII)-induced arthritis (CIA) in mice is associated with the major histocompatibilityI-A gene and with as yet poorly defined regulatory molecules of the major histocompatibility complex (MHC) class II antigen processing and presentation pathway. H2-M molecules are thought to be involved in the loading of antigenic peptides into the MHC class II binding cleft. We sequencedH2-Ma, H2-Mb1, andH2-Mb2 genes from CIA-susceptible and-resistant mouse strains and identified four differentMa andMb2 alleles and three differentMb1 alleles defined by polymorphic residues within the predicted peptide binding groove. Most CIA-resistant mouse strains share commonMa, M…

"Se taistelu just ... eri tahojen kanssa viedä tätä asiaa eteenpäin" : CATCH-22 -lasten vanhempien kokemuksia suomalaisesta palvelujärjestelmästä

2002

L'écart et l'entre-deux : traduire la culture

2011

Comparative linguistics seems to suggest that the gap between two languages can be filled by grammar. But mapping the structural gaps between languages hardly makes for the more fundamental gap that is created by the writing of a new text, a supposedly identical addendum to the first. Writing that new text entails questions about the nature of texts, their intentions, their interpretations. Translation must therefore develop a hermeneutical approach. This critical stance is about sorting out what belongs to the languages and what belongs to the text as a specific unit, as a cultural and authorial unit. Because of its cultural nature, translation questions the way one can carry meaning acros…