Search results for "H.P.M."

showing 10 items of 738 documents

The contribution of dynamic marketing capabilities to service innovation and performance

2015

Innovation can become a sustainable competitive advantage for service firms. However, there is lack of empirical research on how marketing capabilities support innovation. This study differentiates between operational and dynamic marketing capabilities, the latter related to strategic marketing, marketing planning and market knowledge skills. Based on a sample of 152 service firms, the results show that operational marketing capabilities influence on those dynamic marketing capabilities. Strategic marketing and marketing planning capabilities impact positively on firm's performance while market knowledge capabilities impact positively on service innovation.

Return on marketing investmentBusiness-to-governmentDigital marketingbusiness.industryStrategy and ManagementManagement Science and Operations ResearchMarketing strategyMarketing mixMarketing managementManagement of Technology and InnovationBusiness and International ManagementMarketingbusinessMarketing researchRelationship marketingInternational Journal of Business Environment
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Harnessing marketing automation for B2B content marketing

2016

The growing importance of the Internet to B2B customer purchasing decisions has motivated B2B sellers to create digital content that leads potential buyers to interact with their company. This trend has engendered a new paradigm referred to as ‘content marketing.’ This study investigates the organizational processes for developing valuable and timely content to meet customer needs and for integrating content marketing with B2B selling processes. The results of this single case study demonstrate the use of marketing automation to generate high-quality sales leads through behavioral targeting and content personalization. The study advances understanding of the organizational processes that su…

Return on marketing investmentContent marketingsocial mediasosiaalinen mediatapaustutkimuscase studyMarketing management0502 economics and businessMarketingmarketing and sales alignmentnew technologiesMarketing researchRelationship marketingta512digitaalinen markkinointiMarketingDigital marketingbusiness.industryMarketing effectiveness05 social sciencesMarketing strategysales funnelComputingMilieux_COMPUTERSANDSOCIETYdigital marketing050211 marketingbusiness050203 business & managementIndustrial Marketing Management
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Factors affecting Finnish consumers' intention to receive SMS marketing: a conceptual model and an empirical study

2008

The study examines factors that affect consumers' intentions to participate in mobile marketing and explores the relationship between consumers' intentions to participate in mobile marketing and their experience with mobile marketing. The authors develop and test a research model with a sample of 4062 mobile phone users. The empirical model highlights that Perceived Utility (PU), context, credibility and Perceived Social Utility (PSU) are the main contributors to consumers' intentions to participate in mobile-marketing initiatives. The paper provides several contributions to both theory and practice.

Return on marketing investmentDigital marketingbusiness.industryAdvertisingQuantitative marketing researchGeneral Business Management and AccountingComputer Science ApplicationsEmpirical researchMobile phoneCredibilityMarketingbusinessMarketing researchRelationship marketingInternational Journal of Electronic Business
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Marketing communication metrics for social media

2011

The objective of this paper is to develop a conceptual framework for measuring the effectiveness of social media marketing communications. Specifically, we study whether the existing marketing communications performance metrics are still valid in the changing digitalised communications landscape, or whether it is time to rethink them, or even to devise entirely new metrics. Recent advances in information technology and marketing bring a need to re-examine measurement models. We combine two important research topics and set directions for potential future research. Metrics to measure marketing communications performance have developed towards a customer orientation. There is no broadly accep…

Return on marketing investmentKnowledge managementmarkkinoinnin tehokkuuden mittaaminenComputer sciencesocial media marketingQuantitative marketing researchmarkkinointiviestintäMarketing scienceMarketing managementsosiaaliset verkostotqualitative metricsmarketing communications marketing performanceMarketingMarketing researchRelationship marketingMarketingfinancial metricsDigital marketingbusiness.industryperformance measurementquantitative metricsMarketing strategyComputer Science Applicationssocial networks.laadullinen mittaaminenbusinessInternational Journal of Technology Marketing
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A new marketing mix model to rescue the hospitality industry: Evidence from Egypt after the Arab Spring

2017

After January 25th 2011 Egypt witnessed political, economic and social instability leading to drastic consequences in the hospitality and tourism industry. Thus unstable situation reflected on the deteriorated occupancy percentages that led to declined profit margins, higher employee layoffs and degraded quality of product and services. The objectives of this research is to examine how the Egyptian hospitality properties manage this dilemma through their marketing practices, and to propose a new marketing mix model that adds new layers of depth to the traditional marketing mix model. A methodological framework was designed to help in the assessment process of management practices pertaining…

Return on marketing investmentMarketing mix modelinglcsh:BusinessTourismMarketing managementddc:650lcsh:Financelcsh:HG1-99990502 economics and businessMarketingRelationship marketingH19business.industryTransition processMarketing effectivenessM31Crisis management05 social sciencesM10Economía AplicadaHotel industryMarketing mixHospitality industryMarketing strategyJ5Marketing mixM100Turismo [5312.90 Economía Sectorial]050211 marketingBusinesslcsh:HF5001-6182050203 business & managementFuture Business Journal
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Contributions to the study of returns to education : the Tunisian case

2016

In Tunisia, enrollment rates in tertiary education had soared up over the past two decades. A significant increase of student annual flows imposed the implementation of reforms that led to an increase in the number of higher education institutions and universities. One of the challenges in Tunisia and many African countries is to improve the efficiency of education systems to promote employability and graduates employment. This thesis discuss the question of the efficiency of education from an economic approach based on returns to education in the labor market. The first chapter analyses private returns to education particularly higher education in African countries. Our findings highlight …

Return to educationEvaluation randomiséRendement de l’éducationSchooling EffectEntrepreneurshipModèles multiniveauxMultilevel Models[SHS.ECO] Humanities and Social Sciences/Economics and FinanceProgram evaluationEffet établissementEntrepreneuriat
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Unexpected substitution of dominant rotavirus G genotypes in French hospitalized children over five consecutive seasons.

2009

International audience; The study was designed to evaluate the circulation of group A rotaviruses in French hospitalized children, and to detect unusual strains. This prospective study was conducted from 2001 to 2006 in children consulting for acute diarrhea at the pediatric emergency department in three French University Hospitals. The rotaviruses were detected by rapid test and genotyped by RT-PCR on the basis of their outer capsid proteins VP4 (P-type) and VP7 (G-type). The stools from 757 children were analyzed. G1P[8] strains were predominant (44.0%), followed by G9P[8] (17.7%), G3P[8] 13.1%, G4P[8] (9.5%), and G2P[4] (1.8%); mixed rotavirus infections occurred in 2.3%. G9 rotaviruses …

Rotavirus[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiologyvirusesmedicine.disease_causeFecesfluids and secretionsMedical microbiology[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseasesRotavirusGenotypeProspective StudiesProspective cohort studyChildAntigens ViralComputingMilieux_MISCELLANEOUS[SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology0303 health sciencesbiologyReverse Transcriptase Polymerase Chain Reactionvirus diseasesGeneral MedicineHospitals3. Good healthInfectious DiseasesChild Preschool[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/VirologyAcute Disease[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]FranceMicrobiology (medical)Diarrheamedicine.medical_specialtyAdolescentReoviridae[ SDV.MP.VIR ] Life Sciences [q-bio]/Microbiology and Parasitology/VirologyRotavirus Infections03 medical and health sciences[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]medicineHumansTypingSerotyping030304 developmental biologyMolecular epidemiology030306 microbiologybusiness.industryInfant NewbornInfant[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologybiology.organism_classification[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyVirology[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human geneticsEl NiñoCapsid ProteinsbusinessEuropean journal of clinical microbiologyinfectious diseases : official publication of the European Society of Clinical Microbiology
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Targeting SARS-CoV-2 Main Protease for Treatment of COVID-19: Covalent Inhibitors Structure-Activity Relationship Insights and Evolution Perspectives

2022

The viral main protease is one of the most attractive targets among all key enzymes involved in the SARS-CoV-2 life cycle. Covalent inhibition of the cysteine145 of SARS-CoV-2 MPRO with selective antiviral drugs will arrest the replication process of the virus without affecting human catalytic pathways. In this Perspective, we analyzed the in silico, in vitro, and in vivo data of the most representative examples of covalent SARS-CoV-2 MPRO inhibitors reported in the literature to date. In particular, the studied molecules were classified into eight different categories according to their reactive electrophilic warheads, highlighting the differences between their reversible/irreversible mech…

SARS-CoV-2COVID-19Viral Nonstructural ProteinsAntiviral AgentsSettore CHIM/08 - Chimica FarmaceuticaCOVID-19 Drug TreatmentCovalent inhibitorsMolecular Docking SimulationCysteine EndopeptidasesStructure-Activity RelationshipMain ProteaseDrug DiscoveryMolecular MedicineHumansProtease InhibitorsCysteineCoronavirus 3C Proteases
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Heteroaromatic Inhibitors of the Astacin Proteinases Meprin α, Meprin β and Ovastacin Discovered by a Scaffold-Hopping Approach.

2020

Abstract Astacin metalloproteinases, in particular meprins α and β, as well as ovastacin, are emerging drug targets. Drug‐discovery efforts have led to the development of the first potent and selective inhibitors in the last few years. However, the most recent compounds are based on a highly flexible tertiary amine scaffold that could cause metabolic liabilities or decreased potency due to the entropic penalty upon binding to the target. Thus, the aim of this study was to discover novel conformationally constrained scaffolds as starting points for further inhibitor optimization. Shifting from flexible tertiary amines to rigid heteroaromatic cores resulted in a boost in inhibitory activity. …

ScaffoldTertiary amineStereochemistryCell SurvivalAntineoplastic Agentsscaffold hoppingMatrix metalloproteinaseScaffold hoppinghydroxamate01 natural sciencesBiochemistryHydrocarbons AromaticmetalloproteinasesStructure-Activity RelationshipmeprinVery Important PaperDrug DiscoveryTumor Cells CulturedHumansProtease InhibitorsGeneral Pharmacology Toxicology and PharmaceuticsAminesPharmacologyDose-Response Relationship DrugMolecular StructureFull Paper010405 organic chemistryChemistryOrganic ChemistryMetalloendopeptidasesFull PapersovastacinRecombinant Proteinsheteroaromatics0104 chemical sciences010404 medicinal & biomolecular chemistryMetalloproteasesMolecular MedicineAstacinDrug Screening Assays AntitumorSelectivityChemMedChem
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Concepts and Framework

2014

Alongside defining the term ‘event’, the relevant literature has developed five characteristics for distinguishing events: (1) the event schedule, (2) the event strategy, (3) the event period, (4) the event content and (5) the event size (Preuss et al., 2009, 26). While singular events in the area of art and culture (including historical jubilee celebrations and concerts) are considered as being of vital importance, singular events in sports are rather an exception and comparatively limited (ibid.) Events in the area of sport are typically considered as regularly held events within an event series (Kurscheidt, 2006). It is however to be differentiated between guest-events being held from a …

Schedule (workplace)Host countryHistoryEvent (computing)World championshipMedia studiesmedia_common.cataloged_instanceEuropean unionPeriod (music)media_commonTerm (time)
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