Search results for "H1"
showing 10 items of 1219 documents
The oceanic feeling in painterly creativity
2014
The oceanic feeling has been a relatively persistent topic of discussion in both creativity research and aesthetics. Characterized by a sensation of self-boundary dissolution, the feeling has often been reported to involve experiences of fusion with various objects, including works of art. In this article, I will discuss the oceanic feeling in the specific context of painterly creativity. I will begin by arguing that the oceanic feeling cannot be classified as an emotion, mood, or bodily feeling in the established senses of these terms. I will then introduce philosopher Matthew Ratcliffe’s theory of existential feelings to help formulate a more accurate view of the oceanic feeling. More spe…
Neoestetica: un archetipo disciplinare
2011
The paper focuses on Du Bos’ contribution to the birth of aesthetics. Du Bos elaborates – in an anticlassicistical tone – three central notions: 1) that of “artificial passion”, 2) of the taste of “the public” (which is in turn linked to a peculiar conception of “feeling”) and 3) of “artistic genius”. The main tenet will be that such an approach does lead to a “philosophy of fine arts” (or of “artistic beauty”), i.e. the discipline with which modern aesthetics ends up identifying at the end of the xviii century. Hence the theoretical, and not just historical, interest for this author, especially when having an eye to neoaesthetics, viz. aesthetics as begotten by the crisis of the modern aes…
DesignArt. Ibridazioni creative tra arte e oggetti d’uso
2016
Oggi il mondo dell’arte si apre a un’ibridizzazione di forme e generi. La bellezza e la creatività, categorie fondamentali dell’arte secondo la tradizione idealistica e romantica, trovano nella vita quotidiana nuovi territori da colonizzare. In questo panorama di esteticità diffusa un fenomeno acquista particolare interesse: la DesignArt. La DesignArt costituisce un’intersezione tra due ambiti della creatività storicamente volti l’uno a progettare per l’industria oggetti seriali, utili ed esteticamente gradevoli, l’altro a ideare opere uniche e belle, ma senza scopo. Il luogo precipuo della DesignArt è l’ambiente vissuto, dove contemplazione e consumo si intrecciano in un’esperienza sineste…
Federalism and Ethnic Minorities in Ethiopia: Ideology, Territoriality, Human Rights, Policy
2014
In 1994 Ethiopia has adopted a new constitution, considered one of the most advanced in terms of provisions for human rights. The progressive ratification of several international treaties on minority rights had already begun in 1991, immediately after the fall of the Derg regime. This progress has brought Ethiopia into the UN monitoring system, but the review of the official UN documents reveals the mismatch between the mentioned constitutional and international steps and the on-ground situation. This article considers two possible causes of this gap. The first is the particular form of ethnic federalism, first introduced with the Charter of the Transitional Government of Ethiopia and late…
EL FÚTBOL COMO POTENCIADOR DE TURISMO DEPORTIVO
2018
El turismo deportivo se puede definir como un viaje de ocio con el fin de participar, de distintas formas, en actividades físico-deportivas. Respecto al fútbol, sus encuentros constituyen grandes eventos deportivos, atracciones donde el turista vivencia, principalmente de forma pasiva, distintas actividades, ya sea como espectador o como visitante de las atracciones turístico-futbolísticas. Sin duda, el fútbol tiene un importante valor turístico, en especial para la estructura turística local, incidiendo de manera directa en aspectos como la promoción y difusión de un destino turístico. En este marco, los clubs de fútbol se convierten en promotores turísticos de su ciudad, además de desarro…
Prácticas de recursos humanos y su impacto en los resultados de innovación: una revisión teórica
2013
El presente artículo tiene como objetivo la realización de una revisión teórica con la finalidad de identificar las prácticas de Recursos Humanos más analizados respecto a los resultados de innovación y, como resultado, poner de manifiesto otras variables no consideradas hasta la fecha pera que también tengan incidencia en dicha relación. Así pues, autonomía, participación, formación, sistemas de recompensas, trabajo en equipo, reclutamiento y selección, además del desarrollo de carrera profesional, afectarían positivamente los resultados de la innovación a través de la creatividad y la gestión del conocimiento. La estructura y cultura organizativa jugarían un papel moderador en esta relaci…
El derecho de participación en las políticas sociales: el proceso participativo para la elaboración de la Ley valenciana de Servicios Sociales
2020
espanolEl derecho de participacion ciudadana en la configuracion de las politicas sociales es un elemento esencial en las nuevas formas de gobernanza y en el ejercicio de la gobernabilidad de los estados democraticos. En el siguiente articulo, se presenta el ejemplo de la Ley Valenciana de Servicios Sociales, desgranando las diferentes fases del proceso de elaboracion y profundizando en las aportaciones de los distintos actores sociales. Dicho proceso, comprendido entre el periodo 2015–2019, consto de cuatro etapas con una triple finalidad: 1) hacer participes a la pluralidad de actores (ciudadania, profesionales, entidades locales, entidades del tercer sector, personas expertas) y partidos…
Human Memory Th17 Cell Populations Change Into Anti-inflammatory Cells With Regulatory Capacity Upon Exposure to Active Vitamin D
2019
Autoimmune diseases are characterized by an aberrantly activated immune system, resulting in tissue damage and functional disability in patients. An important therapeutic goal is to restore the deregulated immunological balance between pro- A nd anti-inflammatory T cells. This imbalance is illustrated by elevated levels and activity of memory Th17 cell populations, such as Th17, Th1/Th17, and Th17.1 cells, in various autoimmune diseases. These cells are characterized by the chemokine receptor CCR6, RORC expression and production of IL-17A, IFNγ, and TNFα. Using rheumatoid arthritis (RA) as a model of autoimmune disease, we here demonstrate that pro-inflammatory memory CCR6+ Th cells can swi…
Osteoclast Immunosuppressive Effects in Multiple Myeloma: Role of Programmed Cell Death Ligand 1
2018
Immunomodulatory drugs and monoclonal antibody-based immunotherapies have significantly improved the prognosis of the patients with multiple myeloma (MM) in the recent years. These new classes of reagents target malignant plasma cells (PCs) and further modulate the immune microenvironment, which prolongs anti-MM responses and may prevent tumor occurrence. Since MM remains an incurable cancer for most patients, there continues to be a need to identify new tumor target molecules and investigate alternative cellular approaches using gene therapeutic strategies and novel treatment mechanisms. Osteoclasts (OCs), as critical multi-nucleated large cells responsible for bone destruction in >80% …
Azithromycin Differentially Alters TCR-Activated Helper T Cell Subset Phenotype and Effector Function
2020
In addition to their antibiotic activities, azithromycin (AZM) exhibits anti-inflammatory effects in various respiratory diseases. One of the potent anti-inflammatory mechanisms is through inhibition of CD4+ helper T (Th) cell effector function. However, their impact on specific Th subset is obscure. Herein, we demonstrate the cellular basis of phenotypic and functional alterations associated with Th subsets following AZM treatment in vitro. Using well-characterized Th subset specific chemokine receptors, we report significant suppression of T cell receptor (TCR)-stimulated hyperactivated CCR4+CXCR3+ (Th0) expansion compared to CCR4-CXCR3+ (Th1-like) and CCR4+CXCR3- (Th2-like) cells. Intere…