Search results for "H1"
showing 10 items of 1219 documents
La evaluación de un programa de formación con profesorado de escuelas de personas adultas del Perú
2018
Se presenta la evaluación de un programa de formación con profesorado de Escuelas de Personas Adultas. El Seminario en Gestión Pedagógica para Directores, Subdirectores y Docentes nombrados de los Centros de Educación Básica Alternativa Públicos se desarrolla en España desde la Universitat de València. El programa se diseña a partir de un proceso consensuado entre las instituciones y autoridades implicadas, vinculando un adecuado análisis de necesidades previo. Asimismo, el seminario se diseña combinando tres aproximaciones de formación: conferencias sobre temáticas específicas, visitas a lugares y diferentes recursos educativos y cursos formativos. Diseñar un programa de formación sobre ed…
Association of ADH4 genetic variants with alcohol dependence risk and related phenotypes: results from a larger multicenter association study
2011
Genetic variants of the alcohol-metabolizing enzyme ADH4, located on chromosome 4q22-4q23, have been related to alcohol dependence (AD) risk in previous research. The aim of this association study in a large multicenter sample of alcohol-dependent individuals and controls is to confirm ADH4 single nucleotide polymorphism (SNP) and haplotype association with AD and relevant related phenotypes. One thousand, six hundred and twenty-two (1622) inpatient subjects and 1469 control subjects with DSM-IV. AD from four addiction treatment centres were included. Characteristics of AD and related phenotypes including alcohol withdrawal, Cloninger's type I and II and first ages of drinking, regular drin…
Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster
2011
Alcohol dependence (AD) is an important contributory factor to the global burden of disease. The etiology of AD involves both environmental and genetic factors, and the disorder has a heritability of around 50%. The aim of the present study was to identify susceptibility genes for AD by performing a genome-wide association study (GWAS). The sample comprised 1333 male in-patients with severe AD according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, and 2168 controls. These included 487 patients and 1358 controls from a previous GWAS study by our group. All individuals were of German descent. Single-marker tests and a polygenic score-based analysis to assess the …
Histamine inhibits spontaneous activity of the uterus of the progesterone-treated rat
1993
Percezione e immagine
2006
Il titolo individua un argomento che per la sua vastità, qualunque sia il taglio con cui si decide di affrontarlo, risulta impossibile nelle logiche spazio-temporali di un convegno. È stato affettuosamente “estorto”, ma innanzi tempo, quando foggetto doveva ancora essere concepito. Si sa: le parole hanno la capacità, con piccoli aggiustamenti, di adattarsi a cose diverse e apparire, di volta in volta, persino appropriate, come se fossero state ritagliate proprio per quella o quel- raltra cosa...
AMPLIFICANDO TÉCNICAMENTE LA VIRTUD - UTOPÍA Y MORAL ENHANCEMENT
2017
En este artículo analizo el proyecto de perfeccionar moralmente al ser humano por mediode la eugenesia desde el ángulo brindado por la utopía. Ello nos permitirá conectar lostrabajos de la actual Moral Enhancement con obras literarias y teóricas del siglo XIX einicios del XX donde la confianza en el progreso de la ciencia y la tecnología ya alentaba laconvicción de que la humanidad sería mejorada artificialmente a todos los niveles en elfuturo, incluido el nivel moral. La exposición hará hincapié en las diferencias y similitudesexistentes entre los dos paradigmas eugenésicos (el victoriano y el liberal) que dichaconvicción ha originado hasta ahora. También en los impactos negativos que a mi…
«Evo-devo meets the Mind». La questione dell’esperienza estetica e l’evoluzionismo contemporaneo, dall’ipotesi degli adattamenti modulari all’interpr…
2013
Is it achievable to read aesthetic experience as a modular adaptation, and what would be its implication on the image of man, on aesthetics and on evolutionary theory itself? An alternative path is offered by evolutionary morphology, starting from the elaboration of a biologic concept of organism and from the notion of homology of function as a system of interconnections organized in a hierarchy. We deduce the possibility of thinking the peculiar innovation of aesthetic experience in an evolutionary way.
Neuroestetica e fenomenologia della percezione pittorica e musicale
2008
Neuroaesthetics aims at working out a neurobiological theory of aesthetic experience that accounts for neural invariants of perceptual properties fo artworks. In this paper, arguments are proposed that deal with the specification of the intended domain of application, its implications for neurobiological evidence that qualifies as explanans, the contribution that a rigorous phenomenological explanation of the perceptual variety in visual and musical arts can give to an evolutionary account of the cognitive skills underlying arts.
Pho85 and PI(4,5)P(2) regulate different lipid metabolic pathways in response to cold
2019
Lipid homeostasis allows cells to adjust membrane biophysical properties in response to changes in environmental conditions. In the yeast Saccharomyces cerevisiae, a downward shift in temperature from an optimal reduces membrane fluidity, which triggers a lipid remodeling of the plasma membrane. How changes in membrane fluidity are perceived, and how the abundance and composition of different lipid classes is properly balanced, remain largely unknown. Here, we show that the levels of phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2], the most abundant plasma membrane phosphoinositide, drop rapidly in response to a downward shift in temperature. This change triggers a signaling cascade trans…
Empirical determination of Einstein A-coefficient ratios of bright [Fe II] lines
2014
The Einstein spontaneous rates (A-coefficients) of Fe+ lines have been computed by several authors with results that differ from each other by up to 40%. Consequently, models for line emissivities suffer from uncertainties that in turn affect the determination of the physical conditions at the base of line excitation. We provide an empirical determination of the A-coefficient ratios of bright [Fe II] lines that would represent both a valid benchmark for theoretical computations and a reference for the physical interpretation of the observed lines. With the ESO-Very Large Telescope X-shooter instrument between 3000 Å and 24700 Å, we obtained a spectrum of the bright Herbig-Haro object HH 1. …