Search results for "H30"

showing 7 items of 1587 documents

Exosomal and Plasma Non-Coding RNA Signature Associated with Urinary Albumin Excretion in Hypertension

2022

Non-coding RNA (ncRNA), released into circulation or packaged into exosomes, plays important roles in many biological processes in the kidney. The purpose of the present study is to identify a common ncRNA signature associated with early renal damage and its related molecular pathways. Three individual libraries (plasma and urinary exosomes, and total plasma) were prepared from each hypertensive patient (with or without albuminuria) for ncRNA sequencing analysis. Next, an RNA-based transcriptional regulatory network was constructed. The three RNA biotypes with the greatest number of differentially expressed transcripts were long-ncRNA (lncRNA), microRNA (miRNA) and piwi-interacting RNA (piR…

MaleRNA UntranslatedhypertensionQH301-705.5non-coding RNABlood PressureexosomesArticleCatalysisInorganic ChemistryAlbuminuriaHumansGene Regulatory NetworksPhysical and Theoretical ChemistryBiology (General)Molecular BiologyQD1-999Spectroscopyplasmaurinary albumin excretion; hypertension; exosomes; plasma; non-coding RNAGene Expression ProfilingOrganic ChemistryLiquid BiopsyGeneral MedicineComputer Science ApplicationsChemistryGene Expression Regulationurinary albumin excretionFemaleDisease SusceptibilityTranscriptomeCell-Free Nucleic AcidsBiomarkersInternational Journal of Molecular Sciences
researchProduct

Dentinal microcracks after root canal instrumentation using instruments manufactured with different NiTi alloys and the SAF system: A systematic revi…

2021

Aim: The aim of this systematic analysis was to assess the prevalence of dentinal microcracks at various levels (3, 6, and 9 mm from the apex) after using instruments made with conventional, R-Phase, and M-Wire NiTi alloys and the SAF system. Materials and Methods: Electronic searches were conducted in the databases Embase, Cochrane Library, Scopus, PubMed, and Web of Science. To arrange search methods, “MeSH” terms and/or keywords typically associated with the subject were paired with the Boolean operators “AND” and “OR.” Additional searches were conducted on the websites of four separate endodontic journals. After reading the titles and excluding duplicates, 1000 of the 1343 documents ori…

TechnologyMtwo filesWeb of scienceQH301-705.5Computer scienceQC1-9990206 medical engineeringDentistryTF Adaptive files02 engineering and technologyRoot canal instrumentationSystem a03 medical and health sciencesReciproc files0302 clinical medicineSelf-Adjusting File systemGeneral Materials ScienceBiology (General)QD1-999InstrumentationFluid Flow and Transfer ProcessesR-phasebusiness.industryTPhysicsProcess Chemistry and TechnologyGeneral Engineering030206 dentistryWAVEONE filesEngineering (General). Civil engineering (General)ProTaper Next files020601 biomedical engineeringComputer Science ApplicationsChemistryK3XF filesProTaper Universal filesMartensite-wireNickel titaniumDentin microcracksLower prevalenceNiTi instrumentsTA1-2040business
researchProduct

Mean square rate of convergence for random walk approximation of forward-backward SDEs

2020

AbstractLet (Y,Z) denote the solution to a forward-backward stochastic differential equation (FBSDE). If one constructs a random walk$B^n$from the underlying Brownian motionBby Skorokhod embedding, one can show$L_2$-convergence of the corresponding solutions$(Y^n,Z^n)$to$(Y, Z).$We estimate the rate of convergence based on smoothness properties, especially for a terminal condition function in$C^{2,\alpha}$. The proof relies on an approximative representation of$Z^n$and uses the concept of discretized Malliavin calculus. Moreover, we use growth and smoothness properties of the partial differential equation associated to the FBSDE, as well as of the finite difference equations associated to t…

Statistics and ProbabilityDiscretizationapproximation schemeMalliavin calculus01 natural sciences010104 statistics & probabilityconvergence rateMathematics::ProbabilityConvergence (routing)random walk approximation 2010 Mathematics Subject Classification: Primary 60H10FOS: MathematicsApplied mathematics0101 mathematicsBrownian motionrandom walk approximationMathematicsstokastiset prosessitSmoothness (probability theory)konvergenssiApplied Mathematics010102 general mathematicsProbability (math.PR)Backward stochastic differential equationsFunction (mathematics)Random walkfinite difference equation[MATH.MATH-PR]Mathematics [math]/Probability [math.PR]Rate of convergencebackward stochastic differential equations60G50 Secondary 60H3060H35approksimointidifferentiaaliyhtälötMathematics - Probability
researchProduct

Predictors of therapy failure in newly diagnosed pulmonary tuberculosis cases in Beira, Mozambique.

2018

Abstract Objective Tuberculosis (TB) remains a major global health issue, ranking in the top ten causes of death worldwide. A deep understanding of factors influencing poor treatment outcomes may allow the development of additional treatment strategies, focused on the most vulnerable groups. Aims of the study were: (i) to evaluate the treatment outcome among TB subjects followed in an outpatient setting and (ii) to analyze factors associated with treatment failure in newly diagnosed patients with pulmonary TB in Beira, the second largest city of Mozambique. Results A total of 301 TB adult patients (32.6% females) were enrolled. Among them, 62 (20.6%) experienced a treatment failure over a 6…

Genetics and Molecular Biology (all)0301 basic medicineMaleTreatment outcomeAntitubercular Agentslcsh:MedicineHIV InfectionsSettore MED/42 - Igiene Generale E ApplicataBiochemistryTreatment failureBody Mass Index0302 clinical medicineTherapy failureOutpatientsGlobal healthOdds Ratio030212 general & internal medicineTreatment Failurelcsh:QH301-705.5MozambiqueCoinfectionGeneral MedicinePrognosisMozambique; Therapy failure; Tuberculosis; Biochemistry Genetics and Molecular Biology (all)Research NoteEducational StatusFemaleAdultEmploymentmedicine.medical_specialtyTuberculosisAdolescent030106 microbiologyNewly diagnosedGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesPulmonary tuberculosisInternal medicinemedicineHumansTuberculosislcsh:Science (General)PovertyTuberculosis PulmonaryAdult patientsbusiness.industrylcsh:RMalnutritionmedicine.diseaseTuberculosis Mozambique Therapy failurelcsh:Biology (General)Hiv statusbusinesslcsh:Q1-390BMC research notes
researchProduct

Editorial: Physiology and Pathophysiology of Heat Shock Protein 60

2020

business.industrypost translational modificationshepatocellular carcinomaacquired chaperonopathieBioinformaticsHsp60Biochemistry Genetics and Molecular Biology (miscellaneous)BiochemistryPathophysiologypost translational modificationlcsh:Biology (General)cardiovascular diseasegenetic chaperonopathieHeat shock proteinPosttranslational modificationMedicineHSP60acquired chaperonopathiesbusinessgenetic chaperonopathieslcsh:QH301-705.5Molecular Biologychaperonotherapy
researchProduct

Single-cell analysis of the ventricular-subventricular zone reveals signatures of dorsal and ventral adult neurogenesis

2021

The ventricular-subventricular zone (V-SVZ), on the walls of the lateral ventricles, harbors the largest neurogenic niche in the adult mouse brain. Previous work has shown that neural stem/progenitor cells (NSPCs) in different locations within the V-SVZ produce different subtypes of new neurons for the olfactory bulb. The molecular signatures that underlie this regional heterogeneity remain largely unknown. Here, we present a single-cell RNA-sequencing dataset of the adult mouse V-SVZ revealing two populations of NSPCs that reside in largely non-overlapping domains in either the dorsal or ventral V-SVZ. These regional differences in gene expression were further validated using a single-nucl…

MaleNervous systemMouseTransgenicneuroscienceMiceNeural Stem CellsLateral VentriclesBiology (General)education.field_of_studyGeneral NeuroscienceNeurogenesisQRGeneral MedicineStem Cells and Regenerative Medicineadult neurogenesismedicine.anatomical_structureolfactory bulbNeurologicalMedicineStem Cell Research - Nonembryonic - Non-HumanFemaleSingle-Cell AnalysisStem cellMicrodissectionneuroblastResearch ArticleQH301-705.51.1 Normal biological development and functioningNeurogenesisSciencePopulationregenerative medicineSubventricular zoneMice TransgenicBiologysingle-cell sequencingGeneral Biochemistry Genetics and Molecular BiologyNeuroblaststem cellsUnderpinning researchGeneticsmedicineAnimalseducationmouseGeneral Immunology and MicrobiologyNeurosciencesStem Cell ResearchOlfactory bulbstem cellnervous systemBiochemistry and Cell BiologyNeuronTranscriptomeNeuroscienceNeuroscienceregional differenceseLife
researchProduct

The Unity of The Mathematical Science and Ethics in terms of evolutionary scale

Hallo, I wish to share with you my view of the possible associations among Entrop

Quantitative Biology::BiomoleculesQH301 BiologyGN AnthropologyQ Science (General)QC00 Physics (General)
researchProduct