Search results for "HAP"

showing 10 items of 2767 documents

Acute inflammatory response after inguinal and incisional hernia repair with implantation of polypropylene mesh of different size.

2005

The purpose of this study was to assess the modifications of interleukin (IL)-6, C-reactive protein (CRP), leukocytes and fibrinogen after implantation of polypropylene mesh.Thirty-six patients were included in this study and divided into two groups. To the first group were allocated patients affected by inguinal hernia and undergoing conventional repair (subgroup Ia) or hernioplasty with 40-cm(2) polypropylene mesh (subgroup Ib). To the second group were allocated patients affected by incisional hernia and undergoing conventional repair (subgroup IIa) or incisional hernia repair with 400-cm(2) polypropylene mesh (subgroup IIb). Peripheral venous blood samples were collected 24 h before sur…

medicine.medical_specialtyIncisional herniaBiocompatible MaterialsHernia InguinalFibrinogenPolypropylenesProsthesis ImplantationmedicineLeukocytesHumansHerniaHerniorrhaphyInflammationbiologybusiness.industryInterleukin-6C-reactive proteinFibrinogenVenous bloodMiddle AgedSurgical Meshmedicine.diseaseSurgeryHernia AbdominalInguinal herniaSurgical meshC-Reactive Proteinbiology.proteinSurgeryFemalebusinessAbdominal surgerymedicine.drugLangenbeck's archives of surgery
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Association of ACACB polymorphisms with obesity and diabetes

2011

El pdf del artículo es la versión pre-print.-- et al.

medicine.medical_specialtyLinkage disequilibriumEndocrinology Diabetes and MetabolismPopulationSingle-nucleotide polymorphismType 2 diabetesBiologyBiochemistryPolymorphism Single NucleotideLinkage DisequilibriumCohort StudiesEndocrinologyInternal medicineGeneticsmedicineHumansObesityAlleleeducationMolecular BiologyAllelesGenetic Association StudiesAgedGeneticsACACBAged 80 and overeducation.field_of_studyHaplotypeAcetyl-CoA carboxylaseType 2 diabetesMiddle Agedmedicine.diseasePostmenopauseEndocrinologyDiabetes Mellitus Type 2HaplotypesACACBCase-Control StudiesFemalePolymorphismsAcetyl-CoA Carboxylase
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New approaches in the treatment of Adamantiades-Behçet's disease.

2005

Purpose of review To update clinicians on the recent advances in the treatment of Adamantiades-Behcet's disease. Recent findings Interferon-α-2a and infliximab have proved able to induce prompt remission in the vast majority of Adamantiades-Behcet's patients with DMARD-resistant uveoretinitis. Efficacy of interferon-α-2a has also been reported for mucocutaneous lesions, arthritis, and (more anecdotally) for neuro-Behcet, while results from small case series suggest that infliximab is beneficial for mucocutaneous lesions and (more anecdotally) for arthritis and gastro-intestinal manifestations. Two cases of neuro-Behcet treated with infliximab showed a complete resolution. Finally, in a rand…

medicine.medical_specialtyMucocutaneous zoneArthritisBehcet's diseaseDiseaseInterferon alpha-2Receptors Tumor Necrosis Factorlaw.inventionEtanerceptEtanerceptRheumatologyRandomized controlled triallawAntibodies Monoclonal; Behcet Syndrome; Chaperonin 60; Humans; Immunoglobulin G; Immunologic Factors; Interferon-alpha; Receptors Tumor Necrosis Factor; Recombinant ProteinsmedicineHumansImmunologic FactorsIFN-α2abusiness.industryBehcet SyndromeAntibodies MonoclonalInterferon-alphaChaperonin 60medicine.diseaseDermatologyeye diseasesInfliximabAdamantiades-Behçet's diseaseInfliximabRecombinant Proteinsstomatognathic diseasesImmunoglobulin GImmunologyTumour necrosis factorbusinessTolerizationUveitismedicine.drugCurrent opinion in rheumatology
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Neo-nervegenesis in 3D dynamic responsive implant for inguinal hernia repair. Qualitative study.

2020

Abstract Background Prosthetic repair of inguinal hernias is one of the most performed surgical procedures. Nevertheless, high rates of complications affect the surgical treatment. Implant fixation, poor-quality tissue ingrowth and mesh shrinkage seem to be involved in postoperative complications, discomfort and chronic pain following inguinal hernia repair. To address these issues a multilamellar shaped 3D dynamic responsive prosthesis has been developed. This new implant, positioned fixation-free to obliterate the hernia opening, thanks its inherent dynamic compliance during inguinal movements, has demonstrated to induce an enhanced biological response. The ingrowth of newly formed muscle…

medicine.medical_specialtyNeo-nervegenesimedicine.medical_treatmentConnective tissueArtificial LimbsHernia InguinalGroinProsthesisProsthesis Implantation03 medical and health sciences0302 clinical medicinePostoperative ComplicationsProstheseBiopsymedicineHumansHerniaTissue scaffoldsHerniorrhaphyQualitative ResearchGroinmedicine.diagnostic_testbusiness.industryInguinal herniaNerveGeneral MedicineSurgical Meshmedicine.diseaseHernia repairSurgerySettore MED/18 - Chirurgia GeneraleInguinal herniamedicine.anatomical_structure030220 oncology & carcinogenesisPrinting Three-DimensionalTissue regeneration030211 gastroenterology & hepatologySurgeryImplantbusinessInternational journal of surgery (London, England)
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n-3 Fatty Acids Modulate T-Cell Calcium Signaling in Obese Macrosomic Rats

2004

Objective: We investigated the effects of a diet containing EPAX-7010, rich in PUFAs such as eicosapentaenoic acid [20:5(n-3)] and docosahexaenoic acid [22:6(n-3)], i.e., a PUFA/EPAX regimen, on T-cell activation in diabetic pregnant rats and their obese pups. Research Methods and Procedures: Mild hyperglycemia in pregnant rats was induced by intraperitoneal injection of streptozotocin on Day 5 of gestation. T-cell blastogenesis was assayed by using 3H-thymidine, whereas intracellular free calcium concentrations ([Ca2+]i) were measured by using Fura-2 in diabetic pregnant rats and their obese offspring. Results: Concavalin-A-stimulated T-cell proliferation was decreased in both pregnant dia…

medicine.medical_specialtyOffspringT-LymphocytesEndocrinology Diabetes and Metabolismmedicine.medical_treatmentIntraperitoneal injectionPregnancy in DiabeticsMedicine (miscellaneous)Gestational AgeLymphocyte ActivationDiabetes Mellitus ExperimentalFetal MacrosomiaEndocrinologyDietary Fats UnsaturatedPregnancyDiabetes mellitusInternal medicineFatty Acids Omega-3Concanavalin AmedicineAnimalsObesityRats Wistarchemistry.chemical_classificationCalcium metabolismbusiness.industryIonomycinPublic Health Environmental and Occupational Healthmedicine.diseaseStreptozotocinEicosapentaenoic acidRatsEndocrinologychemistryDocosahexaenoic acidThapsigarginCalciumFemalebusinessSpleenSignal TransductionFood SciencePolyunsaturated fatty acidmedicine.drugObesity Research
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Community detection-based deep neural network architectures: A fully automated framework based on Likert-scale data

2020

[EN] Deep neural networks (DNNs) have emerged as a state-of-the-art tool in very different research fields due to its adaptive power to the decision space since they do not presuppose any linear relationship between data. Some of the main disadvantages of these trending models are that the choice of the network underlying architecture profoundly influences the performance of the model and that the architecture design requires prior knowledge of the field of study. The use of questionnaires is hugely extended in social/behavioral sciences. The main contribution of this work is to automate the process of a DNN architecture design by using an agglomerative hierarchical algorithm that mimics th…

medicine.medical_specialtyPalliative careCommunity-detection deep neural network (CD-DNN)General Mathematicsmedia_common.quotation_subjectHappinessNetwork scienceNetwork science01 natural sciences010305 fluids & plasmasLikert scalePsychometric scales0103 physical sciencesmedicineCollective wisdom03.- Garantizar una vida saludable y promover el bienestar para todos y todas en todas las edadesQuality (business)010306 general physicsMathematicsmedia_commonArtificial neural networkCommunity detectionbusiness.industryPublic healthDeep learningGeneral EngineeringDeep learningRegression3. Good healthEngineering managementFISICA APLICADAArtificial intelligenceAutomatic architecturebusinessMATEMATICA APLICADA
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Factores de predicción de dosificación inadecuada de rivaroxabán utilizando la ecuación de CKD-EPI

2021

Yes

medicine.medical_specialtyPatientsCKD-EPI:Diseases::Hemic and Lymphatic Diseases::Hematologic Diseases::Blood Coagulation Disorders [Medical Subject Headings]Dosislcsh:RC870-923:Anatomy::Cardiovascular System::Blood Vessels::Arteries::Aorta [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]DosageRivaroxabanRivaroxabánmedicineRenal insufficiency chronicInsuficiencia renal crónicaGynecology:Diseases::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Renal Insufficiency::Renal Insufficiency Chronic [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Clinical Trials as Topic::Observational Study as Topic [Medical Subject Headings]business.industry:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Dosage Calculations [Medical Subject Headings]lcsh:Diseases of the genitourinary system. Urology:Persons::Persons::Patients [Medical Subject Headings]NephrologyPacientesDosificaciónbusiness:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Prescriptions [Medical Subject Headings]Nefrología
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Effects of military basic training on VO2max, body composition, muscle strength and neural responses in conscripts of different aerobic condition

2019

Summary Study aim: The purpose of this study was to evaluate neuromuscular adaptations in conscripts with different fitness levels (VO2max) during 8 weeks of military basic training (BT). Material and methods: Twenty-four male conscripts (18–21 years) were divided into two groups (Good Fitness [GF] and Low fitness [LF]) based on their VO2max at the beginning of BT. Body mass (BM), fat free mass (FFM) and Fat% were measured after 2, 4, and 7 weeks of training. VO2max, maximal isometric leg press force (MVC), H-reflex (Hmax/Mmax) at rest and V-wave (V/Mmax) during maximal isometric plantarflexion were measured from the soleus muscle at the beginning, after 5, and after 8 weeks of training. Re…

medicine.medical_specialtyPhysiologyPhysical Therapy Sports Therapy and Rehabilitationsotilaskoulutus030204 cardiovascular system & hematologyPhysical education03 medical and health sciences0302 clinical medicinemaksimaalinen hapenottoMedicineQP1-981Orthopedics and Sports MedicineComposition (language)military trainingkehonkoostumusaerobic fitnessneuromuscular adaptationbusiness.industryPublic health030229 sport sciencesSports medicinePhysical therapyMuscle strengthaerobinen suorituskykybusinesshuman activitiesRC1200-1245lihasvoimafysiologiset vaikutuksetBiomedical Human Kinetics
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Muscle Free Fatty-Acid Uptake Associates to Mechanical Efficiency During Exercise in Humans

2018

Intrinsic factors related to muscle metabolism may explain the differences in mechanical efficiency (ME) during exercise. Therefore, this study aimed to investigate the relationship between muscle metabolism and ME. Totally 17 healthy recreationally active male participants were recruited and divided into efficient (EF; n = 8) and inefficient (IE; n = 9) groups, which were matched for age (mean ± SD 24 ± 2 vs. 23 ± 2 years), BMI (23 ± 1 vs. 23 ± 2 kg m−2), physical activity levels (3.4 ± 1.0 vs. 4.1 ± 1.0 sessions/week), and V˙O2peak (53 ± 3 vs. 52 ± 3 mL kg−1 min−1), respectively, but differed for ME at 45% of V˙O2peak intensity during submaximal bicycle ergometer test (EF 20.5 ± 3.5 vs. I…

medicine.medical_specialtyPhysiologyrasvahapotPhysical activitylihaksetMuscle blood flowlcsh:Physiology03 medical and health sciences0302 clinical medicinePhysiology (medical)Internal medicinemedicineskeletal muscleta315aineenvaihduntaSport and Fitness SciencesOriginal Researchhapenottochemistry.chemical_classificationluustolcsh:QP1-981Idrottsvetenskapta1184Fatty acidSkeletal muscle030229 sport sciencesMetabolismRespiratory quotientoxygen uptakeeconomyEndocrinologymedicine.anatomical_structurechemistryBicycle ergometerfree fatty-acidEnergy sourcemetabolism030217 neurology & neurosurgeryFrontiers in Physiology
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Biomechanical and histological evaluation of abdominal wall compliance with intraperitoneal onlay mesh implants in rabbits: A comparison of six diffe…

2012

Abstract Background An ideal prosthetic mesh for incisional hernia repair should mimic the anisotropic compliance of the abdominal wall, and at lower loads should exhibit higher distensibility without impairment of safety at higher loads. This study evaluated the biomechanical properties of six meshes in a rabbit model. Methods New Zealand white rabbits were used for this study. Two meshes of the same brand (Ethicon Physiomesh™, Bard Composix ® L/P, Gore Dualmesh ® , Bard Sepramesh ® , Ethicon Proceed ® or Parietex™ Composite) were implanted into each animal for assessment of intra-abdominal hernia repair, with a total of ten meshes per group. Twelve weeks after implantation, the abdominal …

medicine.medical_specialtyPolyestersmedicine.medical_treatmentBiomedical EngineeringBiophysicsAdhesion (medicine)PolypropylenesDioxanesAbdominal wallAdhesivesMaterials TestingAnimalsMedicinePeritoneal CavityPhysiological reactionHerniorrhaphyMechanical PhenomenaWound HealingMathematical approximationbusiness.industryAbdominal WallIncisional hernia repairProstheses and ImplantsHernia repairmedicine.diseaseBiomechanical PhenomenaSurgeryCompliance (physiology)medicine.anatomical_structurePolydioxanoneRabbit modelFemaleRabbitsbusinessPorosityMedical Engineering & Physics
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