Search results for "HAp"

The human side of leadership: exploring the relationship between servant leadership, organisational facilitators and happiness at work

2018

Although human resource management (HRM) research has established a significant relationship between leadership styles and different attitudinal outcomes, few studies have considered the important role of organisational facilitators as a more proximal outcome of servant leadership to explain happiness at work (HAW). This paper explores the relationships between servant leadership, organisational facilitators and HAW, based on the leader-member exchange (LMX) and job-demands resources (JD-R) theories. Individual-level analyses from a sample of 189 machine operators revealed that organisational facilitators fully mediate the relationship between servant leadership and HAW. The discussion revi…

Liderazgo femenino y felicidad en el trabajo: el papel mediador del intercambio líder-colaborador

2018

Objetivo: el objetivo de este artículo es examinar el papel del liderazgo femenino en la felicidad en el trabajo de sus colaboradores. Además, se analiza el papel mediador de la relación entre el líder y el colaborador, entendida como el intercambio líder-colaborador (LMX). Método: se ha utilizado la encuesta como método de investigación; se analizaron datos cuantitativos a nivel individual a través de modelos de ecuaciones estructurales. La muestra está compuesta por 292 empleados no directivos del sector hotelero español, para los que se analiza su percepción individual acerca de las variables objeto de estudio. Resultados: los resultados revelan que el liderazgo femenino ejerce un papel …

Freedom and the Pursuit of Happiness

2014

This book is about the relationship between different concepts of freedom and happiness. The book's authors distinguish three concepts for which an empirical measure exists: opportunity to choose (negative freedom), capability to choose (positive freedom), and autonomy to choose (autonomy freedom). They also provide a comprehensive account of the relationship between freedom and well-being by comparing channels through which freedoms affect quality of life. The book also explores whether the different conceptions of freedom complement or replace each other in the determination of the level of well-being. In so doing, the authors make freedoms a tool for policy making and are able t…

Assessment of the Optimum Linker Tethering Site of Alternariol Haptens for Antibody Generation and Immunoassay Development

2021

Immunochemical methods for mycotoxin analysis require antigens with well-defined structures and antibodies with outstanding binding properties. Immunoreagents for the mycotoxins alternariol and/or alternariol monomethyl ether have typically been obtained with chemically uncharacterized haptens, and antigen conjugates have most likely been prepared with mixtures of functionalized molecules. For the first time, total synthesis was performed, in the present study, to obtain two haptens with opposite linker attachment locations. The functionalized synthetic haptens were purified and deeply characterized by different spectrometric methods, allowing the preparation of bioconjugates with unequivoc…

Synthetic Haptens and Enantioselective Monoclonal Antibodies to the Cyanotoxin Anatoxin‐a

2019

Early warning systems for monitoring toxic events may benefit from the availability of monoclonal antibodies enabling the sensitive and specific detection of anatoxin‐a, a cyanotoxin involved in numerous cases of animal poisoning due to toxic algal blooms in freshwaters. Through the synthesis of three functionalized derivatives of anatoxin‐a, we have succeeded in generating the first‐ever reported immunoreagents (bioconjugates and antibodies) suitable for the development of immunoanalytical approaches aimed at rapid and onsite detection of this harmful cyanotoxin.

Concise and modular synthesis of regioisomeric haptens for the production of high-affinity and stereoselective antibodies to the strobilurin azoxystr…

2011

The immune response to regioisomeric haptens of azoxystrobin with varied derivatization sites was studied. Based on the Sonogashira and Suzuki-Miyaura couplings and following a straightforward modular design, we have synthesized four haptens with the same linker anchored through C-C bonds and located at different sites of the molecule. The most stereoselective antibodies were produced from immunogens with the spacer arm at a distal position from the β-methoxyacrylate moiety characteristic of strobilurins. Moreover, we observed that assay cross-reactivity was reliant on the functionalization site of the competitor derivative. Finally, the antibody binding site was explored using synthetic ch…

The affect of contact force sensations on user performance in virtual assembly tasks

2007

International audience; Abstract The development of a realistic virtual assemblyenvironment is challenging because of the complexity of the physical processes and the limitation of available VRtechnology. Many research activities in this domain pri-marily focused on particular aspects of the assembly task such as the feasibility of assembly operations in terms of interference between the manipulated parts. The virtualassembly environment reported in this research is focusedon mechanical part assembly. The approach presented ad-dresses the problem of part-to-part contacts during themating phase of assembly tasks. The system describedcalculates contact force sensations by making their inten-s…

On the distribution of haptoglobin types in Iceland

1963

Assessment of the interpretability of data mining for the spatial modelling of water erosion using game theory

2021

Abstract This study undertook a comprehensive application of 15 data mining (DM) models, most of which have, thus far, not been commonly used in environmental sciences, to predict land susceptibility to water erosion hazard in the Kahorestan catchment, southern Iran. The DM models were BGLM, BGAM, Cforest, CITree, GAMS, LRSS, NCPQR, PLS, PLSGLM, QR, RLM, SGB, SVM, BCART and BTR. We identified 18 factors usually considered as key controls for water erosion, comprising 10 factors extracted from a digital elevation model (DEM), three indices extracted from Landsat 8 images, a sediment connectivity index (SCI) and three other intrinsic factors. Three indicators consisting of MAE, MBE, RMSE, and…

Smoking cessation opportunities in severe mental illness (tobacco intensive motivational and estimate risk — TIMER—): study protocol for a randomized…

2019

There is an increased risk of premature death in people with severe mental illness (SMI). Respiratory disorders and cardiovascular disease are leading causes of increased mortality rates in these patients, and tobacco consumption remains the most preventable risk factor involved. Developing new tools to motivate patients towards cessation of smoking is a high priority. Information on the motivational value of giving the lung age and prevention opportunities is unknown in this high-risk population. In the context of community care, screening and early detection of lung damage could potentially be used, together with mobile technology, in order to produce a prevention message, which may provi…