Search results for "HBO"
showing 10 items of 311 documents
Classification of spatio-temporal point pattern in the presence of clutter using K-th nearest neighbour distances
2019
In a point process spatio-temporal framework, we consider the problem of features detection in the presence of clutters. We extend the methodology of Byers and Raftery (1998) to the spatio-temporal context by considering the properties of the K-th nearest-neighbour distances. We make use of the spatio-temporal distance based on the Euclidean norm where the temporal term is properly weighted. We show the form of the probability distributions of such K-th nearest-neighbour distance. A mixture distribution, whose parameters are estimated with an EM algorithm, is used to classify points into clutters or features. We assess the performance of the proposed approach with a simulation study, togeth…
A two-armed bandit collective for hierarchical examplar based mining of frequent itemsets with applications to intrusion detection
2014
Published version of a chapter in the book: Transactions on Computational Collective Intelligence XIV. Also available from the publisher at: http://dx.doi.org/10.1007/978-3-662-44509-9_1 In this paper we address the above problem by posing frequent item-set mining as a collection of interrelated two-armed bandit problems. We seek to find itemsets that frequently appear as subsets in a stream of itemsets, with the frequency being constrained to support granularity requirements. Starting from a randomly or manually selected examplar itemset, a collective of Tsetlin automata based two-armed bandit players - one automaton for each item in the examplar - learns which items should be included in …
RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy
2014
Macroautophagy is a degradative pathway that sequesters and transports cytosolic cargo in autophagosomes to lysosomes, and its deterioration affects intracellular proteostasis. Membrane dynamics accompanying autophagy are mostly elusive and depend on trafficking processes. RAB GTPase activating proteins (RABGAPs) are important factors for the coordination of cellular vesicle transport systems, and several TBC (TRE2-BUB2-CDC16) domain-containing RABGAPs are associated with autophagy. Employing C. elegans and human primary fibroblasts, we show that RAB3GAP1 and RAB3GAP2, which are components of the TBC domain-free RAB3GAP complex, influence protein aggregation and affect autophagy at basal an…
162P Prevalence and spectrum analysis of germline BRCA1 and BRCA2 variants of unclear significance in HBOC Syndrome: Decoding the mysterious signals …
2021
Microsatellite-based species identification method for Drosophila virilis group species
2007
Species of the D. virilis group are widely used in evolutionary research, but the individuals of different species are difficult to distinguish from each other morphologically. We constructed a fast and easy microsatellite-based identification method for the species of the group occurring sympatrically in northern Europe. The neighbor joining tree based on 14 microsatellite loci also gave a good resolution of the species divergence pattern in the whole group.
A GIS-Based Method for Analysing the Association Between School-Built Environment and Home-School Route Measures with Active Commuting to School in U…
2020
In the current call for a greater human health and well-being as a sustainable development goal, to encourage active commuting to and from school (ACS) seems to be a key factor. Research focusing on the analysis of the association between environmental factors and ACS in children and adolescents has reported limited and inconclusive evidence, so more knowledge is needed about it. The main aim of this study is to examine the association between different built environmental factors of both school neighbourhood and home-school route with ACS of children and adolescents belonging to urban areas. The ACS level was evaluated using a self-reported questionnaire. Built environment variables (i.e.,…
School Neighbourhood Built Environment Assessment for Adolescents’ Active Transport to School: Modification of an Environmental Audit Tool and Protoc…
2020
School neighbourhood built environments (SN-BE) can influence adolescents&rsquo
THE EXPECTED DEMOGRAPHIC INFLUENCES ON THE PROVISION OF EDUCATION SERVICES IN THE NEIGHBOURHOODS OF RIGA
2020
This paper discusses the spatial extent of population change and provides new insights into the relationships between demographic characteristics and the provision of education services in urban neighbourhoods of Riga. Thus, our empirical evidence confirms that the provision of social infrastructure is fundamentally dependent on the nature of demographic processes. The aim of this paper is twofold: to explore the spatial extent of changes in the number of pre-school and school-aged children in Riga, and to assess how the demographic change of particular age cohorts are associated with the provision of educational establishments at the neighbourhood level. Using available statistics and base…
A Mosaic of Suburbs: The Historic Boroughs of Palermo
2013
Palermo suburbs have grown and developed at the expense of becoming isolated from other parts of the city. Ancient boroughs have been eradicated, alongside their urban identities. The challenges of a cosmopolitan and global world are felt even in middle-sized, fringe cities like Palermo, as its suburbs are forced to become tiles of an urban mosaic that is created by urban development. It is the duty of urban scholars to clarify and strengthen the relationships between these urban parts, and in the process restore the neglected notion of neighborhood. By overcoming the distinction between cities and urban sprawl, the controversial dispute may be resolved by urban scholars. Through historica…
Between Strategic Cooperation and Distrustful Neighbourhood. Polish-German relations in the agendas of Polish governments, 1990–2019
2019
Since 1989 the building of new Polish-German relations has been carried out in the dimensions of both time (historical reconciliation) and space (reintegration eastern and western parts of Europe). This determines their fundamental importance for contemporary Europe. This article presents an analysis of Polish-German relations from the perspective of issue salience. The source base of this paper comprises Addresses by the Ministers of Foreign Affairs (AMFAs), i.e. annual speeches given by foreign ministers presenting the major goals of Poland’s foreign policy. It makes it possible to adopt a long-term perspective (1990-2018). The quantitative analysis was based on the rules of the Comparati…