Search results for "HD"
showing 10 items of 4547 documents
Aika aikaansa kutakin
2023
Iso-Britannian lehdistö ja Unkarin vuoden 1956 kansannousu
1997
Substantial Fat Loss in Physique Competitors Is Characterized by Increased Levels of Bile Acids, Very-Long Chain Fatty Acids, and Oxylipins.
2022
Funder: Finnish Foundation for Cardiovascular Research
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
2012
BACKGROUND: High plasma HDL cholesterol is associated with reduced risk of myocardial infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes are randomly assigned at meiosis, are independent of non-genetic confounding, and are unmodified by disease processes, mendelian randomisation can be used to test the hypothesis that the association of a plasma biomarker with disease is causal. METHODS: We performed two mendelian randomisation analyses. First, we used as an instrument a single nucleotide polymorphism (SNP) in the endothelial lipase gene (LIPG Asn396Ser) and tested this SNP in 20 studies (20,913 myocardial infarction cases, 95,407 controls). Se…
Pharmacologic screen identifies active combinations with BET inhibitors and LRRK2 as a novel putative target in lymphoma
2022
Inhibitors of the Bromo- and Extra-Terminal domain (BET) family proteins have strong preclinical antitumor activity in multiple tumor models, including lymphomas. Limited single-agent activity has been reported in the clinical setting. Here, we have performed a pharmacological screening to identify compounds that can increase the antitumor activity of BET inhibitors in lymphomas. The germinal center B-cell like diffuse large B-cell lymphoma (DLBCL) cell lines OCI-LY-19 and WSU-DLCL2 were exposed to 348 compounds given as single agents at two different concentrations and in combination with the BET inhibitor birabresib. The combination partners included small molecules targeting important bi…
Political risks: the “red shift” in debt sustainability analysis
2020
Political stability and economic policy uncertainty can be key determinants of sovereign debt dynamics, and we show how they can be incorporated in debt sustainability analysis. We distinguish between short-term ambiguity and long-term uncertainty about political risk factors, and using a combination of narrative scenarios and calibrated probabilistic scenarios we obtain a comprehensive heatmap of high-risk debt dynamics. We use Italy as an interesting case study and demonstrate a “red shift” in the assessment of vulnerabilities when accounting for political risks. Ignoring these risks can lead to excessive optimism and wrong decisions.
The public–private sector wage gap in Latvia
2018
This study investigates the public-private sector wage gap in Latvia using microdata from the labour force survey. The severity of public sector wage cuts employed as a response to the economic crisis and subsequent recovery provides a test bed to analyse whether and how the public-private sector wage gap has adjusted after consolidation-driven wage cuts. Findings reveal that the observed wage gap is slightly in favour of the public sector; however, once differences in individual characteristics and selection effects are considered, results point to a private sector wage premium. Findings also suggest that the private sector wage premium has increased since the pre-crisis period. A signific…
FORECASTING THE LABOUR FORCE DEMAND AND SUPPLY IN LATVIA / LATVIJOS DARBO JĖGOS PAKLAUSOS IR PASIŪLOS MODELIAVIMAS
2008
The purpose of this paper is to analyse the problems of Latvian labour market and its possible development. An econometric model for labour force demand and supply forecasting is elaborated and it comprises 120 professions, 37 aggregated groups of professions and covers time period 2007–2030. The results of the quantitative and qualitative Employers’ Survey are analysed and taken into account. The novelty of this research study lies in the complex approach to the labour force demand and supply analyses and to the forecasts to the Latvian economy in general and for its 15 separate sectors. Santrauka Šio straipsnio tikslas – išanalizuoti Latvijos darbo rinkos problemas ir galimus pokyčius. Su…
Halu kielessä eli prosessin alaisen subjektin ongelma Markku Lahtelan teksteissä Se ja Yksinäinen mies : lacanilais-kristevalainen psykoanalyyttislin…
2000
Development of iron oxide/activated carbon nanoparticle composite for the removal of Cr(VI), Cu(II) and Cd(II) ions from aqueous solution
2018
Iron oxide (Fe3O4) and iron oxide/activated carbon (Fe3O4/AC) were fabricated by co-precipitation method for the removal of Cr(VI), Cu(II) and Cd(II) ions from aqueous solution in batch mode. These nanoparticles were characterized by BET, FTIR, XRD, SEM/TEM and VSM. The optimum conditions for the removal of ions were pH = 2 for Cr(VI) and 6 for Cu(II) and Cd(II), initial metal ion concentration = 50 mg L−1, nanoparticle dose = 50 mg/10 mL, temperature = 25 ± 1 °C, shaking speed = 180 rpm and contact time = 3 h. The equilibrium data of ions sorption were well described by Langmuir, Freundlich, Redlich-Peterson and Intraparticle Diffusion model. The R2 values obtained by Langmuir model were h…