Search results for "HD"
showing 10 items of 4547 documents
Power training and postmenopausal hormone therapy affect transcriptional control of specific co-regulated gene clusters in skeletal muscle
2010
At the moment, there is no clear molecular explanation for the steeper decline in muscle performance after menopause or the mechanisms of counteractive treatments. The goal of this genome-wide study was to identify the genes and gene clusters through which power training (PT) comprising jumping activities or estrogen containing hormone replacement therapy (HRT) may affect skeletal muscle properties after menopause. We used musculus vastus lateralis samples from early stage postmenopausal (50–57 years old) women participating in a yearlong randomized double-blind placebo-controlled trial with PT and HRT interventions. Using microarray platform with over 24,000 probes, we identified 665 diffe…
Plasma lipid, apolipoprotein and Lp(a) levels in elderly normolipidemic women: Relationships with coronary heart disease and longevity
1995
The relation between plasma lipids and coronary heart disease (CHD) in the elderly is still debated, as well as the proposed role of lipoproteins as markers of longevity. In this study both normolipidemic elderly and middle-aged women with CHD showed higher triglycerides and apolipoprotein B levels and lower high-density lipoprotein (HDL)-cholesterol and apolipoprotein A-I levels in comparison with age-matched subjects without CHD. In the middle-aged group, hypertension and HDL-cholesterol levels and, in the elderly group, only HDL-cholesterol levels were independently associated with CHD. No significant difference was found between a group of healthy centenarians and elderly and middle-age…
Muscular transcriptome in postmenopausal women with or without hormone replacement.
2007
The loss of muscle mass and strength with aging is well characterized, but our knowledge of the molecular mechanisms underlying the development of sarcopenia remains incomplete. Although menopause is often accompanied with first signs of age-associated changes in muscle structure and function, the effects of hormone replacement therapy (HRT) or menopause-related decline in estrogen production in the muscles of postmenopausal women is not well understood. Furthermore the knowledge of the global transcriptional changes that take place in skeletal muscle in relation to estrogen status has thus far been completely lacking. We used a randomized double-blinded study design together with an explor…
Ethological analysis of morphine withdrawal with different dependence programs in male mice.
2002
Abstract This work was performed to clarify the differences between a long or short development of morphine dependence as well as between a recently installed or a long-term dependence. Morphine withdrawal in rats is a well-characterized phenomenon but this is not so in mice. A study of the principal withdrawal signs have been performed in mice, evaluating their specificity and particular profile of appearance in each type of dependence. Mice were divided into two groups that received increasing doses of morphine every 24 h, three groups that received increasing doses of morphine twice a day for 3 days, and a control group that received saline. Naloxone-induced opiate withdrawal was evaluat…
Pandemic Prevention and Personality Psychology: Gender Differences in Preventive Health Behaviors during COVID-19 and the Roles of Agreeableness and …
2022
One of the greatest public health crises in recent times, the COVID-19 pandemic, has come with a myriad of challenges in terms of health communication and public cooperation to prevent the spread of the disease. Understanding which are the key determinants that make certain individuals more cooperative is key in effectively tackling pandemics and similar future challenges. In the present study (N = 800), we investigated whether gender differences in compliance with preventive health behaviors (PHB) at the onset of the COVID-19 pandemic could be established, and, if so, whether the personality traits of agreeableness and conscientiousness could help explain this presumed relationship. Consis…
Mitä mieltä, professorit?
2006
25 vuoden ikään ehtinyt Aikuiskasvatus kysyi kaikilta aikuiskasvatuksen professoreiltamme heidän näkemyksiään neljässä asiassa. Kaikkiin ei tarvinnut vastata. Tällaista kysyttiin ja näin vastasivat Yrjö Engeström ja Reijo Miettinen Helsingin yliopistosta, Anneli Eteläpelto Jyväskylän yliopistosta, Jukka Tuomisto ja Juha Suoranta Tampereen yliopistosta, Risto Rinne Turun yliopistosta, Kari E. Nurmi Lapin yliopistosta sekä vt:nä virkaa hoitava Leena Ahteenmäki-Pelkonen Joensuun yliopistosta. Vastausjärjestys on arvottu.
Arithmetical Analysis of Biomolecular Finite Automaton
2013
In the paper we present a theoretical analysis of extension of the finite automaton built on DNA (introduced by the Shapiro team) to an arbitrary number of states and symbols. In the implementation we use a new idea of several restriction enzymes instead of one. We give arithmetical conditions for the existence of such extensions in terms of ingredients used in the implementation.
De la reproduction au récit de soi : engendrement et destruction des images dans Fun Home et Are You My Mother? d'Alison Bechdel
2022
International audience
Raconter ses lectures, se raconter : plaisir de lire, identité et émancipation chez Alison Bechdel
2017
National audience; Cette communication interroge l’importance donnée aux liens entre plaisir de lire et identité (en particulier identité lesbienne) dans les récits autobiographiques d’Alison Bechdel. Celle-ci met en scène une première opposition entre les lectures d’enfance, caractérisée par l’immersion narrative, et les lectures légitimes que son père tente de lui imposer à mesure qu’elle grandit, avec une injonction à lire qu’elle finit par intérioriser. Cette opposition prend une valeur plus directement identitaire lorsque la lecture obligatoire de Ulysses à l’université est systématiquement opposée à la lecture d’un corpus varié d’œuvres gays et lesbiennes au moment de l’éveil politiqu…
Penser la frontière entre essai et autobiographie à partir de la bande dessinée. Are You My Mother? d'Alison Bechdel
2018
Based on Alison Bechdel's autobiographical essay Are You My Mother?, this article is a discussion on two boundaries of the essay : a generic boundary between essay and autobiography, questioned by the possibility of autobiographical essay, and an intermedial boundary challenged by the development of graphic essays in comics. Are You My Mother? is a self-reflexive autobiographical work which describes the author's discovery of psychoanalysis and deals at the same time with mother-child relationships and the continuity between novel writing, autobiography and psychoanalysis, thus articulating autobiographical material and general thoughts. The book can be described in particular as a consiste…