Search results for "HD"
showing 10 items of 4547 documents
Sosiaaliset suhteet ja sosiaalinen kompetenssi 3.-4. luokkalaisilla
2008
Huostaanotettujen lasten taustamuuttujat sosiaalilautakunnan pöytäkirjojen perusteella
2003
Julkisen ja salaisen rajat maakuntien EU-tukihallinnossa : kartoitus journalismin ehdoista ja mahdollisuuksista uudessa julkisuuskulttuurissa
1997
Biohajoavien ja biostabiilien polymeerien aiheuttamat pehmytkudosreaktiot
2007
Randomized Trial : D-Glyceric Acid Activates Mitochondrial Metabolism in 50–60-Year-Old Healthy Humans
2021
Background: Based on earlier studies, natural metabolite D-glyceric acid (DGA) does not seem to play any role in whole-body metabolism. Nevertheless, one ethanol oxidation-related rat study with controversial results raised our interest. According to preparatory studies for the regulatory approval of DGA, some highly conserved mechanism seems to subtly activate the cellular energy metabolism. Therefore, the present 25-days double-blind human study with placebo control was initiated. Purpose: The main target in the present study with 27 healthy 50–60-year-old human volunteers was to find out whether an “acute” 4-days and a longer 21-days exogenous DGA regimen caused moderate activation of th…
Heme Oxygenase-1 and Blood Bilirubin Are Gradually Activated by Oral D-Glyceric Acid
2022
It has been shown that small doses of oral D-glyceric acid (DGA) activate mitochondrial metabolism and reduce inflammation among 50–60-year-old healthy volunteers. The present results with the same small doses reveal that after a 4-day DGA regimen, a dose of DGA activated the HO-1 pathway acutely, while enhanced inflammatory status after the 4-day DGA regimen seemed to be able to downregulate the HO-1 pathway in non-acute measurement. Blood bilirubin was strongly upregulated towards the end of the altogether 21-day study period with positive associations towards improved inflammation and reduced blood triglycerides. After the 4-day DGA regimen, hepatic inflow of blood bilirubin with albumin…
Exercise and inflammation with special reference to resistance training
2018
The aim of the present dissertation was to examine the acute and chronic effects of resistance exercise on inflammation markers in young men. In addition, the effect of combined resistance and endurance training on inflammation was assessed. The present dissertation consisted of four studies. Acute inflammation response was evaluated using cross-sectional design after hypertrophic and maximal (n=12) resistance exercise bouts (I). In addition, acute inflammation was examined before and after resistance training (RT) consisting either hypertrophic or maximal explosive (n=8) resistance exercise bouts (RE) (II). The effect of RT on basal levels of markers of systemic inflammation was evaluated …
Lääkeaineanalytiikan oppimateriaalin kehittäminen ammatilliseen laboratorioalan koulutukseen
2015
Tässä Pro gradu -tutkielmassa on suunniteltu lääkeaineanalytiikan opetusmateriaalia laboratorioalan ammatillisen koulutuksen valinnaisiin opintoihin. Kirjallisuusosaan on koottu tietoja tulehduskipulääkkeistä, niiden sitoutumisesta plasman proteiineihin sekä lääkeainepitoisuuden analysoinnista ja menetelmän validoinnista. Analysoinnissa on keskitytty erilaisiin plasman proteiinien erotustapoihin ja näytteen derivatisointiin. Analyysilaitteistoina olevista kaasu- ja nestekromatografeista on kirjallisuusosaan kerätty oleellisimmat tiedot. Menetelmän validointia on käsitelty lähtökohtaisesti biologisten näytteiden kannalta. Kirjallisuusosaan on kerätty tietoja, joita voi käyttää teoriaopetukse…