Search results for "HD"
showing 10 items of 4547 documents
Commento a "Resistin, visfatin, leptin and omentin are differently related to hormonal and metabolic parameters in growth hormone-deficient children "
2016
Background Nonostante siano ampiamente riconosciuti gli effetti del GH sul tessuto adiposo e il ruolo metabolico delle adipocitochine, i dati in letteratura sono piuttosto discordanti. Obiettivo Scopo di questo studio è stato quello di valutare l’impatto della terapia con GH su una serie di adipocitochine aventi un chiaro ruolo metabolico ma poco studiate in questo contesto clinico. Materiali e metodi In questo studio prospettico sono stati valutati 31 bambini prepuberi (25 M, 6 F; età media di 8.5 ± 1.6 anni) affetti da deficit di GH (GHD) isolato e trattati con GH per almeno 12 mesi consecutivi e 30 controlli sani appaiati per età e sesso. Sia in baseline (in tutti i soggetti) che dopo 12…
Commento a "The impact of real practice inappropriateness and devices' inefficiency to variability in growth hormone consumption"
2015
Questo lavoro di Spandonaro e collaboratori è uno dei pochi lavori scientifici prodotti volti ad analizzare un aspetto poco conosciuto e meritevole di attenzione e opportune riflessioni riguardo alla terapia con ormone somatotropo (GH).
Istutuspäällikkö Gaddin julkiset matkaraportit 1763–1765
2022
Artikkelissa tarkastellaan Inrikes Tidningarissa julkaistuja raportteja Pehr Adrian Gaddin (1727–1797) matkoista Suomessa vuosina 1763–1765. Tekstit sekä rikastavat käsitystä Gaddin toiminnasta istutuspäällikkönä että antavat esimerkin mahdollisesta julkisuuden käytöstä vapaudenajan lopun Ruotsissa.
Female survivors’ experiences of authorities’ actions in cases of partner stalking
2020
Previous studies have shown that civil authorities fail to understand the nature of stalking and the harmful consequences it causes victims. The aim of this study was to investigate how the victims of partner stalking had perceived the actions of civil authorities and the stalking investigation process. The data were drawn from conversations among members of an internet-based peer support group for female victims of partner stalking. We identified four main categories of victims’ experiences pertaining to authorities’ actions and the investigation process: authorities’ problems in dealing with stalking, dissatisfaction with the investigation process, trust in the authorities and expectation…
Challenging Unequal Gendered Conventions in Heterosexual Relationship Contexts through Affective Dissonance
2019
In Nordic countries, intimate relationships are routinely compared against ideals of gender equality, even though equality is not always achieved in everyday life. In this article, we analyse interviews with women that lived in unconventional relationships: mid- to later-life women in relationships with younger men, and bisexual women who have had relationships with people of different genders. The women’s expectations of equality and reciprocity in heterosexual relationships collided with the lived reality of inequalities, causing affective dissonance. We identify three strategies that women use to deal with this affective dissonance. In the first strategy, unequal relationship patterns ar…
Evidence for shared environmental contributions to attention-deficit/hyperactivity traits. A twin study
2019
Background and objectives: Behavior-genetic analyses have shown that measurements of inattention and hyperactivity-impulsivity are genetically-influenced. In view of limited studies on ADHD (Attention deficit hyperactivity disorder) in Spanish samples, this study aims to explore the genetic architecture of ADHD symptoms; inattention and hyperactivity-impulsivity in a Spanish twin schoolchildren sample. Methods: Participants were 258 pairs of adolescent Spanish twins. Symptoms of ADHD, inattention and hyperactivity-impulsivity were assessed by means of a sub-scale of the Strengths and Difficulties Questionnaire. Univariate twin models, according to sex, were run to assess the heritability of…
Synthesis of Enaminones-Based Benzo[d]imidazole Scaffold: Characterization and Molecular Insight Structure
2020
(E)-1-(1H-Benzo[d]imidazol-2-yl)-3-(dimethylamino)prop-2-en-1-one 2 was synthesized by one-pot synthesis protocol of 2-acetyl benzo[d]imidazole with dimethylformamide dimethylacetal (DMF-DMA) in xylene at 140 °
Synthesis, X-ray Structure, Conformational Analysis, and DFT Studies of a Giant s-Triazine bis-Schiff Base
2021
The current work involves the synthesis of 2,2′-(6-(piperidin-1-yl)-1,3,5-triazine-2,4-diyl)bis(hydrazin-2-yl-1-ylidene))bis(methanylylidene))diphenol 4, characterization, and the DFT studies of the reported compound. The crystal unit cell parameters of 4 are a = 8.1139(2) Å, b = 11.2637(2) Å, c = 45.7836(8) Å. The unit cell volume is 4184.28(15) Å3 and Z = 4. It crystallized in the orthorhombic crystal system and Pbca space group. The O…H, N…H, C…H, H…H and C…C intermolecular contacts which affect the crystal stability were quantitatively analyzed using Hirshfeld calculations. Their percentages were calculated to be 9.8, 15.8, 23.7, 46.4, and 1.6% from the whole contacts occurred in the cr…
Synthesis, and Molecular Structure Investigations of a New s-Triazine Derivatives Incorporating Pyrazole/Piperidine/Aniline Moieties
2021
In this work, we synthesized two new s-triazine incorporates pyrazole/piperidine/aniline moieties. Molecular structure investigations in the light of X-ray crystallography combined with Hirshfeld and DFT calculations were presented. Intermolecular interactions controlling the molecular packing of 4-(3,5-dimethyl-1H-pyrazol-1-yl)-N-phenyl-6-(piperidin-1-yl)-1,3,5-triazin-2-amine; 5a and N-(4-bromophenyl)-4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(piperidin-1-yl)-1,3,5-triazin-2-amine; 5b were analyzed using Hirshfeld calculations. The most dominant interactions are the H...H, N...H and H...C contacts in both compounds. The N...H and H...C interactions in 5a and the N...H, Br...H and H...H interacti…
Solution- and gas-phase study of binding of ammonium and bisammonium hydrocarbons to oxacalix[4]arene carboxylate
2023
Oxacalixarenes represent a distinctive class of macrocyclic compounds, which are closely related to the parent calixarene family, offering binding motifs characteristic of calixarenes and crown ethers. Nevertheless, they still lack extensive characterization in terms of molecular recognition properties and the subsequent practical applicability. We present here the results of binding studies of an oxacalix[4]arene carboxylate macrocycle toward a variety of organic ammonium cationic species. Our results show that the substituents attached to the guest ammonium compound largely influence the binding strengths of the host. Furthermore, we show that the characteristic binding pattern changes up…