Search results for "HEE"
showing 10 items of 1797 documents
Weak and Strong Compensation for the Prioritization of Public Investments: Multidimensional Analysis for Pools
2015
Despite the economic crisis still heavily affecting most of Europe, a possible resumption can be found in the revitalization of public and private investments. These investments should be directed not only towards the strategic areas of infrastructures and production, but also to those which allow for a higher level of the quality of life (sports facilities, parks, etc.). In such cases, the need to balance the reasons of financial sustainability with environmental and social profiles is even more evident. Thus, multicriteria techniques, supporting complex assessments, should be implemented together with a monetary feasibility study (cost-benefit analysis). Multidimensional methods allow for…
Multicriteria Prioritization for Multistage Implementation of Complex Urban Renewal Projects
2015
Renewal projects on neighborhood scale often include several sub projects aiming at fulfill the different functions of urban areas, while public funds or activated public-private partnership can be insufficient to face the implementation of subprojects simultaneously. Therefore single parts of wider projects are frequently realized at different period of time, according to the availability of public funds or the interest of private partners in the most profitable projects. Although a major organizational effort of funding could be necessary, a more rational approach is required, which will be able to identify the most suitable sequence of realization ensuring the greatest advantage if non c…
Supporting Small Medium Enterprises planning through the use of a step-by-step System Dynamics model building process
2011
This paper aims to support small medium enterprises (SMEs) in business planning through the use of system dynamics models. In particular, it has been hypothesized that through the use of a step-by-step system dynamics model building process SMEs’ entrepreneurs can better understand the net of cause-and-effect relationships underlying company financial and non-financial results. Such an approach also enables decision makers to improve their understanding about the figures portrayed in a balance sheet. In order to reach such a goal, this study has been carried out through the use of a case-study. The small company investigated is a leather handcraft operating in Indonesia. The paper makes e…
Incremental forming using KUKA KR210-2 industrial robot - research regarding design rules and process modelling
2021
Incremental sheet forming (ISF) process show a great potential in the manufacturing of small series production or prototype development parts. One of the sheet metal forming process, where the contact between punch and metal sheet is in a single point, is known as single point incremental forming (SPIF). The part is manufacture with a simple tool, known as punch, that performs a series of combined movements on the vertically and horizontally directions. The paper introduces a study regarding the design rules and process modelling of this unconventional process, by means of a KUKA KR210-2 industrial robot as technological equipment able to control the correlated movement of the punch. Supple…
Quantitative Analysis of Prion-Protein Degradation by Constitutive and Immuno-20S Proteasomes Indicates Differences Correlated with Disease Susceptib…
2004
Abstract The main part of cytosolic protein degradation depends on the ubiquitin-proteasome system. Proteasomes degrade their substrates into small peptide fragments, some of which are translocated into the endoplasmatic reticulum and loaded onto MHC class I molecules, which are then transported to the cell surface for inspection by CTL. A reliable prediction of proteasomal cleavages in a given protein for the identification of CTL epitopes would benefit immensely from additional cleavage data for the training of prediction algorithms. To increase the knowledge about proteasomal specificity and to gain more insight into the relation of proteasomal activity and susceptibility to prion diseas…
Identification of enolase as a plasminogen-binding protein in excretory-secretory products ofFasciola hepatica
2004
AbstractWe have followed a combined proteomic approach to identify proteins of Fasciola hepatica that could be involved in host–parasite interactions. Using two-dimensional gel electrophoresis, far Western immunoblot and mass spectrometry analyses, we have identified the enolase enzyme, present in the excretory/secretory materials of F. hepatica, as a human plasminogen-binding protein. This enzyme has an apparent molecular weight of 47 kDa with pI ranging from 6.2 to 7.2. These results suggest that enolase could act as a plasminogen receptor.
Slipshod utterances : a study of mislanguage
1992
Theoretical Perspectives and Therapeutic Approaches in Music Therapy with Families
2021
Music therapists have described the importance of working collaboratively with family members in various populations throughout the history of the profession. Despite the growing amount of literature, not enough is known regarding the scope of theoretical perspectives and therapeutic approaches that guide family centered music therapy. The aim of this international survey study was to better understand the professional perspectives and approaches of music therapists who work with families around the world. This article presents the results of the survey where a total of 125 responses were analysed. Participants’ responses indicated that music therapy with families is well established as an …