Search results for "HIF"
showing 10 items of 1515 documents
Regional Powers as Leaders or Rambos? The Ambivalent Behaviour of Brazil and South Africa in Regional Economic Integration
2013
The behaviour of regional powers towards their own regions is often volatile in the developing world, which leads to unstable integration processes. This article argues that this volatility is due to limited intra-regional gains from regional integration in developing regions, which implies that the behaviour of regional powers is constrained by extra-regional economic interests. When regional integration is not in conflict with extra-regional interests, regional powers provide regional leadership. However, when extra-regional interests are in conflict with regional integration, regional powers become regional Rambos. This argument is illustrated with the two examples of Brazil's behaviour …
El sector no lucrativo en el marco de la nueva era tecnológica: el desafío del Crowdfunding social en España. Análisis del caso de la asociación Alba…
2017
Los albores del siglo XXI se presentan a las economías y las sociedades en el marco de un desafiante doble cambio de paradigma. Uno, alentado por el neoliberalismo gobernante en gran parte del mundo avanzado, que ha provocado que la propia sociedad admita la arresponsabilidad de las estructuras gobernantes en la prestación de los servicios que componen el Estado del bienestar. Otro, tecnológico, que ha cambiado el modo en que la sociedad se informa, se comunica y se relaciona. Frente a estas dos realidades la sociedad civil ha tomado conciencia de su papel transformador e impulsor de cambios, así como de las crecientes necesidades de atención social que han surgido en este principio de sigl…
Reciprocal regulation of the human sterol regulatory element binding protein (SREBP)-1a promoter by Sp1 and EGR-1 transcription factors.
2007
AbstractSterol regulatory element binding protein (SREBP)-1a is a transcription factor that is highly expressed in actively growing cells, and is involved in the biosynthesis of cholesterol, fatty acids and phospholipids. We have mapped the minimal human SREBP-1a promoter region to 75bp upstream of the translation start site where we discovered a functional role for the 3 GC-boxes containing overlapping sites for the Sp1 and EGR-1 transcription factors. Intact SP1-binding sites are essential for promoter activity, whereas EGR-1 suppresses the transcription of the human SREBP-1a promoter. These results reveal a novel physiologically relevant transcriptional mechanism for the reciprocal regul…
Initial state radiation experiment at MAMI
2014
In an attempt to contribute further insight into the discrepancy between the Lamb shift and elastic scattering determinations of the proton charge radius, a new experiment at MAMI is underway, aimed at measuring proton form-factors at very low momentum transfers by using a new technique based on initial state radiation. This paper reports on the conclusions of the pilot measurement performed in 2010, whose main goal was to check the feasibility of the proposed experiment and to recognize and overcome any obstacles before running the full experiment. The modifications to the experimental apparatus are then explained which significantly improved the quality of data collected in the full scale…
Exactly solvable model of two three-dimensional harmonic oscillators interacting with the quantum electromagnetic field: The far-zone Casimir-Polder …
2005
We consider two three-dimensional isotropic harmonic oscillators interacting with the quantum electromagnetic field in the Coulomb gauge and within dipole approximation. Using a Bogoliubov-like transformation, we can obtain transformed operators such that the Hamiltonian of the system, when expressed in terms of these operators, assumes a diagonal form. We are also able to obtain an expression for the energy shift of the ground state, which is valid at all orders in the coupling constant. From this energy shift the nonperturbative Casimir-Polder potential energy between the two oscillators can be obtained. When approximated to the fourth order in the electric charge, the well-known expressi…
Energy level shifts of a uniformly accelerated atom in the presence of boundary conditions
2009
We discuss the radiative level shifts of an atom moving with uniform acceleration near an infinite reflecting plate. We first consider the case of a two-level system interacting with a massless scalar field in the vacuum state. The acceleration of the two-level atom is supposed in a direction parallel to the conducting plate. We evaluate the contribution of vacuum fluctuations and of the radiation reaction field to the energy shift of the atomic levels, and discuss their behaviour as a function of the atomic acceleration and of the atom-plate distance. Then, we investigate the more general case of an hydrogen atom accelerating near a perfectly reflecting plate and interacting with the elect…
Cathodoluminescence study of undoped GaN films: Experiment and calculation
2009
Abstract In this paper, we report the theoretical and experimental results of cathodoluminescence (CL) from GaN layers grown at 800 °C by metal organic vapor phase epitaxy (MOVPE) on silicon substrate. The CL spectra recorded at room temperature reveal the near band-edge emission at 3.35–3.42 eV and a broad yellow luminescence at 2.2 eV. The CL depth analysis at constant power excitation shows inhomogeneous CL distribution in depth of these emissions as the electron beam increases from 3 to 25 keV. There appears a blue shift of the CL band-edge peaks with increasing sample depth. This behavior is explained by a change of the fundamental band gap due to residual strain and the local temperat…
Nuclear magnetic shielding constants in the CC2 model
1997
Abstract Test calculations of nuclear magnetic shielding constants in the CC2 model are performed using the gauge-including atomic orbital approach. Absolute shielding constants are reported for reprsentative first-row hydrides, a few multiply bonded molecules and some challenging cases. The performance of CC2 is analyzed by comparison with experimental data and results from calculations employing more sophisticated treatments of electron correlation. In most cases, CC2 shieldings and chemical shifts are close to those obtained at second-order perturbation theory, despite the fact that the CC2 model includes an approximate treatment of orbital relaxation effects at the correlated level.
Electron correlation effects on the calculated 13C NMR spectra of vinyl cations
1997
Abstract A study of calculated 13C NMR chemical shifts in vinyl cations is presented. The sensitivity of predicted isotropic shifts to correlation, basis set and geometry effects is explored. In order to obtain accurate estimates that are reasonably well converged with respect to further improvements in theory, it appears that the CCSD(T) method must be used with a basis of triple-zeta plus polarization quality on the carbon atoms. Second-order many-body perturbation theory performs adequately for all carbons except for that bearing the formal positive charge, while the self-consistent field approximation cannot be relied upon to predict even the correct qualitative ordering in the spectrum…
1H nmr chemical shifts of [14]annulenes and their dianion salts
1987
Abstract The bridged (14]annulene 2 was reduced into its dianion and the structure of the dianion salt was proven by chemical and spectroscopic means. The 1H NMR spectroscopic properties of 2 are similar to those of the structurally related bridged [14]annulene 1 , whereas the corresponding dianions 2 2- and 1 2- are strikingly different. The geometries of 1 and 2 and their dianions were studied by means of a modified π-SCF force field approach. Almost planar perimeters without significant bond length alternation are obtained for the neutral annulenes 1 and 2 , whereas their dianions are characterized by structures with reduced symmetry. The 1H chemical shifts of the bridged [14]annulenes a…