Search results for "HIF"

showing 10 items of 1515 documents

RELIABILITY OF THE DETECTION OF THE BARYON ACOUSTIC PEAK

2008

The correlation function of the distribution of matter in the universe shows, at large scales, baryon acoustic oscillations, which were imprinted prior to recombination. This feature was first detected in the correlation function of the luminous red galaxies (LRG) of the Sloan Digital Sky Survey (SDSS). The final release (DR7) of the SDSS has been recently made available, and the useful volume is about two times bigger than in the old sample. We present here, for the first time, the redshift space correlation function of this sample at large scales together with that for one shallower, but denser volume-limited subsample drawn from the 2dF redshift survey. We test the reliability of the det…

Physicsmedia_common.quotation_subjectAstrophysics (astro-ph)FOS: Physical sciencesAstronomy and AstrophysicsAstrophysics::Cosmology and Extragalactic AstrophysicsAstrophysicsCorrelation function (astronomy)AstrophysicsRedshift surveyGalaxyRedshiftBaryonDistribution (mathematics)Space and Planetary ScienceSkyBaryon acoustic oscillationsAstrophysics::Galaxy Astrophysicsmedia_commonThe Astrophysical Journal
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XMM-Newton First-Light Observations of the Hickson Galaxy Group 16

2000

This paper presents the XMM-Newton first-light observations of the Hickson-16 compact group of galaxies. Groups are possibly the oldest large-scale structures in the Universe, pre-dating clusters of galaxies, and are highly evolved. This group of small galaxies, at a redshift of 0.0132 (or 80 Mpc) is exceptional in the having the highest concentration of starburst or AGN activity in the nearby Universe. So it is a veritable laboratory for the study of the relationship between galaxy interactions and nuclear activity. Previous optical emission line studies indicated a strong ionising continuum in the galaxies, but its origin, whether from starbursts, or AGN, was unclear. Combined imaging and…

Physicsmedia_common.quotation_subjectAstrophysics::High Energy Astrophysical PhenomenaAstrophysics (astro-ph)Continuum (design consultancy)FOS: Physical sciencesAstronomy and AstrophysicsGalaxies: activeAstrophysicsFirst lightAstrophysics::Cosmology and Extragalactic AstrophysicsGalaxy mergerAstrophysicsGalaxyUniverseRedshiftCompact groupSpace and Planetary ScienceGalaxy groupGalaxies: starburstX-rays: galaxieAstrophysics::Galaxy Astrophysicsmedia_common
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Optical pumping and unstable nuclei

1985

The paper reviews the application of optical pumping to short-lived nuclei, where either the nuclear polarisation is detected by the β-decay asymmetry or the atomic polarisation by Stern-Gerlach-analyzer. Moreover the paper deals with collinear laser spectroscopy on beams of short-lived, mass-separated isotopes. The aim of the experiments is the systematic investigation of nuclear structure through the determination of spin, moments and charge radii from the hyperfine structure and isotopic shift of the atomic spectra. The impact of these experiments on the theory of nuclear forces and structure is discussed by means of a few examples.

Physicsmedia_common.quotation_subjectNuclear structureGeneral Physics and AstronomyAsymmetryOptical pumpingIsotopic shiftNuclear forcePhysics::Atomic PhysicsAtomic physicsNuclear ExperimentSpin (physics)SpectroscopyHyperfine structuremedia_commonAnnales de Physique
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Suppression of soliton self-frequency shift by up-shifted filtering

2002

We propose an efficient method for suppressing the soliton self-frequency shift in high-speed transmission lines by means of up-shifted filters.

Physicssymbols.namesakeOptical fiberElectric power transmissionlawQ factorsymbolsFrequency shiftSoliton (optics)Self-phase modulationMolecular physicsRaman scatteringlaw.inventionNonlinear Guided Waves and Their Applications
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Stark broadening of hydrogen spectral lines with fine structure effects

2004

Formalism and numerical code have been elaborated for calculation of hydrogen line profiles in conditions of plasma in which Stark broadening and fine energy splitting are comparable and it is not possible to neglect either of them. It corresponds to the range of electron densities $10^{11} < N_e ({\rm cm}^{-3}) < 10^{15}$ . Lamb shift and spontaneous emission effects have also been included. Computer simulation method was applied in the calculations. Final results have been compared with experimental and theoretical findings by other authors.

Physicssymbols.namesakeStark effectOptical physicssymbolsHydrogen lineSpontaneous emissionElectronAtomic physicsHydrogen spectral seriesHyperfine structureAtomic and Molecular Physics and OpticsLamb shiftThe European Physical Journal D - Atomic, Molecular and Optical Physics
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Absence of mutual polariton scattering for strongly coupled surface plasmon polaritons and dye molecules with a large Stokes shift

2013

The understanding and control of the dynamics of hybrid modes consisting of strongly coupled surface plasmon polaritons and molecular excitations of dye molecules is of great timely interest, as it allows one to tailor interactions between optical signals as needed for active all-optical devices. Here we utilize dye molecules with an especially large Stokes shift to demonstrate the absence of mutual scatterings among the strongly coupled hybrid modes. We employ a quantum mechanical three-level model and show that the hybrid modes decay via dephasing and internal relaxation of the molecules to a fluorescing state of the dye, which can be used as a measure for the decay. Our results provide e…

Physicsta114Condensed matter physicsScatteringDephasingSurface plasmonRelaxation (NMR)Physics::OpticsCondensed Matter PhysicsMolecular physicsSurface plasmon polaritonElectronic Optical and Magnetic Materialssymbols.namesakeStokes shiftsymbolsPolaritonPhysics::Chemical PhysicsLocalized surface plasmonPhysical Review B
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Lifetime Measurements with the Doppler Shift Attenuation Method Using a Thick Homogeneous Production Target — Verification of the Method

2016

International audience; Doppler Shift Attenuation Method (DSAM) analysis of excited-state lifetimes normally employs thin production targets mounted on a thick stopper foil (“backing”) serving to slow down and stop the recoiling nuclei of interest in a well-defined manner. Use of a thick, homogeneous production target leads to a more complex analysis as it results in a substantial decrease in the energy of the incident projectile which traverses the target with an associated change in the production cross section of the residues as a function of penetration depth. Here, a DSAM lifetime analysis using a thick homogeneous target has been verified using the Doppler broadened lineshapes of γ ra…

Physicsta114Doppler Shift Attenuation Method010308 nuclear & particles physicsbusiness.industryAttenuationlifetime measurementGeneral Physics and Astronomy[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]01 natural sciencessymbols.namesakeOpticsHomogeneous0103 physical sciencessymbols010306 general physicsbusinessDoppler effectFOIL method
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An integrative review of the enjoyment of sadness associated with music

2018

The recent surge of interest towards the paradoxical pleasure produced by sad music has generated a handful of theories and an array of empirical explorations on the topic. However, none of these have attempted to weigh the existing evidence in a systematic fashion. The present work puts forward an integrative framework laid out over three levels of explanation – biological, psycho-social, and cultural – to compare and integrate the existing findings in a meaningful way. First, we review the evidence pertinent to experiences of pleasure associated with sad music from the fields of neuroscience, psychophysiology, and endocrinology. Then, the psychological and interpersonal mechanisms underly…

Pleasuremedia_common.quotation_subjectEmotionsreviewmusiikkiGeneral Physics and AstronomyInterpersonal communication050105 experimental psychologyenjoymentPleasure03 medical and health sciences0302 clinical medicineEmpirical researchtunteetArtificial IntelligencemielihyväHumans0501 psychology and cognitive sciencesValence (psychology)media_commonArt.suruilo05 social sciencesBiological EvolutionSadnessAffectPsychophysiologyFeelingPsychological levelGeneral Agricultural and Biological SciencesPsychologysadnessSocial psychologyMusic030217 neurology & neurosurgeryvalence shiftCognitive psychologyPhysics of Life Reviews
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Gata4 Blocks Somatic Cell Reprogramming By Directly Repressing Nanog

2012

Abstract Somatic cells can be reprogrammed to induced pluripotent stem (iPS) cells by ectopic expression of the four factors Oct4, Klf4, Sox2, and Myc. Here, we investigated the role of Gata4 in the reprogramming process and present evidence for a negative role of this family of transcription factors in the induction of pluripotency. Coexpression of Gata4 with Oct4, Klf4, and Sox2 with or without Myc in mouse embryonic fibroblasts greatly impaired reprogramming and endogenous Nanog expression. The lack of Nanog upregulation was associated with a blockade in the transition from the initiation phase of reprogramming to the full pluripotent state characteristic of iPS cells. Addition of Nanog …

Pluripotent Stem CellsTranscriptional ActivationHomeobox protein NANOGChromatin ImmunoprecipitationTranscription GeneticRex1Kruppel-Like Transcription FactorsDown-RegulationElectrophoretic Mobility Shift AssayBiologyCell LineProto-Oncogene Proteins c-mycKruppel-Like Factor 4MiceSOX2AnimalsRNA MessengerRNA Small InterferingInduced pluripotent stem cellEmbryonic Stem Cellsreproductive and urinary physiologyHomeodomain ProteinsSOXB1 Transcription FactorsNanog Homeobox ProteinCell DifferentiationNanog Homeobox ProteinCell BiologyCellular ReprogrammingEmbryonic stem cellGATA4 Transcription FactorKLF4embryonic structuresHepatocyte Nuclear Factor 3-betaCancer researchMolecular MedicineRNA Interferencebiological phenomena cell phenomena and immunityOctamer Transcription Factor-3ReprogrammingDevelopmental BiologyStem Cells
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Cationic polyaspartamide-based nanocomplexes mediate siRNA entry and down-regulation of the pro-inflammatory mediator high mobility group box 1 in ai…

2015

Abstract High-mobility group box 1 (HMGB1) is a nonhistone protein secreted by airway epithelial cells in hyperinflammatory diseases such as asthma. In order to down-regulate HMGB1 expression in airway epithelial cells, siRNA directed against HMGB1 was delivered through nanocomplexes based on a cationic copolymer of poly(N-2-hydroxyethyl)- d,l -aspartamide (PHEA) by using H441 cells. Two copolymers were used in these experiments bearing respectively spermine side chains (PHEA-Spm) and both spermine and PEG2000 chains (PHEA-PEG-Spm). PHEA-Spm and PHEA-PEG-Spm derivatives complexed dsDNA oligonucleotides with a w/w ratio of 1 and higher as shown by a gel retardation assay. PHEA-Spm and PHEA-P…

Polyaspartamide copolymerNucleic acid-based drugDown-RegulationPharmaceutical ScienceSpermineRespiratory MucosaBiologyTransfectionAirway epithelial cellsNucleic acid-based drugsFlow cytometrychemistry.chemical_compoundCell Line TumorMaterials TestingAirway epithelial cellmedicineHumansElectrophoretic mobility shift assayMTT assayDAPIRNA Small InterferingCytotoxicityPolyhydroxyethyl MethacrylateHMGB1Airway epithelial cells; HMGB1; Nucleic acid-based drugs; PHEA; Polyaspartamide copolymers; Sirnamedicine.diagnostic_testOligonucleotideMammaglobin AfungiGene Transfer TechniquesEpithelial CellsDNAPHEAMolecular biologyNanostructuresPolyaspartamide copolymerschemistrySirnaTrypan bluePeptides
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