Search results for "HIV"
showing 10 items of 1527 documents
Comparative study of degassing membrane modules for the removal of methane from Expanded Granular Sludge Bed anaerobic reactor effluent
2016
Abstract The feasibility of an emergent technology for in situ removal/recovery of methane from the effluent of an Expanded Granular Sludge Bed (EGSB) anaerobic reactor has been studied. For this purpose, the performances of two commercial hollow fibre degassing contactors with different membrane materials – microporous (polypropylene, PP) and non-porous (polydimethylsiloxane, PDMS) – were compared. The influence of water fluxes (Q L /A membrane ranging from 22.6 to 377.4 L h −1 m −2 ), vacuum pressure (140–800 mbar), sweep gas fluxes (Q N2 /A membrane ranging from 0.14 × 10 3 to 4.44 × 10 3 L h −1 m −2 ), and mode of operation (liquid flowing in the lumen side or the shell side) was stu…
Shooting in the ghetto: On the migration of film footage
2013
En 2010, un documental germano-israelí –A Film Unfinished– recuperaba enigmáticos planos rodados por un equipo de cineastas alemanes (Propaganda Kompanien) en el ghetto de Varsovia durante la primavera de 1942. Una porción considerable de estos planos que el Ministerio de Propaganda de Goebbels decidió no utilizar por confusas razones ya había circulado profusamente en films anteriores, desde los años 50. Depositados en los archivos de la DEFA, habían sido utilizados a contrario en primer lugar por cineastas de la RDA y de la DDR: tratando de denunciar a sus autores. Dicho de otro modo, las imágenes llamadas a denigrar a los judíos servían para denunciar a sus autores, convirtiéndose en efi…
Roles of a conserved proline in the internal fusion peptide of Ebola glycoprotein
2004
AbstractThe structural determinants underlying the functionality of viral internal fusion peptides (IFPs) are not well understood. We have compared EBOwt (GAAIGLAWIPYFGPAAE), representing the IFP of the Ebola fusion protein GP, and EBOmut (GAAIGLAWIPYFGRAAE) derived from a non-functional mutant with conserved Pro537 substituted by Arg. P537R substitution did not abrogate peptide-membrane association, but interfered with the ability to induce bilayer destabilization. Structural determinations suggest that Pro537 is required to preserve a membrane-perturbing local conformation in apolar environments.
El Colegio de Barberos y Cirujanos de Valencia: aportación documental
1993
En este trabajo pretendemos aportar nueva información, proveniente de fuentes privadas y desconocidas hasta el momento, en torno al proceso de formación del "Colegio de Cirujanos" de Valencia, que incide en algunos aspectos de su funcionamiento interno.
Por una rebeldía sin resentimiento: contra la desigualdad obscena y el populismo
2017
El autor analiza como causas del malestar actual de la sociedad, de un lado, la indiferencia del sector mejor situado de la población ante el crecimiento de una desigualdad obscena. Y de otro la extensión de los populismos, basados en el resentimiento, fruto de un narcisismo carente de sentido de responsabilidad. Frente a ambos extremos propone una rebeldía contra la injusticia social y económica, que debe ir acompañada del agradecimiento ante la maravilla de la creación. The author approaches the reasons for the general lack of satisfaction in civil society: on one hand the indiference of those who are in a better position and on the other the increase of populism based on resentment and n…
Could Europe Apply a Suitable Control Method for the Small Hive Beetle (Coleoptera: Nitidulidae)?
2022
Abstract The European bee, Apis mellifera L. (Hymenoptera: Apidae), is a fundamental resource for the pollination of a great variety of botanical species used by humans for sustenance. Over the last few decades, bee colonies have become vulnerable to a new pest that has advanced beyond its native sub-Saharan territory: the small hive beetle, Aethina tumida Murray (Coleoptera: Nitidulidae). This currently presents a pressing problem in the United States and Australia, but it has also been recorded in Portugal and Italy and it is likely to spread in the rest of Europe too. This study represents a systematic review, based on EFSA guidelines, of the various control treatments for small hive bee…
Un acquisto da farsi prudenter et sine strepitu: l’arrivo in Vaticana di manoscritti e stampati del Collegio Romano all’inizio del XX secolo
2022
Based on a series of unpublished documents found in the Vatican Library and in the Vatican Archive, this article reconstructs the purchase in 1912 of manuscripts and printed books of the Collegium Romanum by the Vatican Library, during the papacy of Pius X. The purchase negotiations, which took place between June and July 1912, involved the praepositus and the consultor of the Roman province of the Jesuits, Augusto Spinetti and Pietro Tacchi Venturi, and the prefect of the Vatican Library, the Jesuit Franz Ehrle. The volumes arrived in the Vatican Library via the Jesuit novitiate of Villa Torlonia in Castel Gandolfo, where the manuscripts and books were transferred from the Collegium Romanu…
Efficacy and safety of dolutegravir and doravirine dual therapy in the context of antiretroviral therapy switch: 48 weeks analysis.
2022
Dual therapy in HIV represents an attractive opportunity for HIV infected people in virologic suppression Dual therapy regimens should achieve and maintain viral suppression and immunologic control while minimizing short and long term AEs, improve adherence and convenience and reduce drug drug interactions and costs To date, there are few clinical data to support a dual regimen with dolutegravir and doravirine 1 The individual efficacy of both doravirine and dolutegravir suggests that concomitant administration of these two molecules as part of an NRTI sparing regimen could be a viable option, although to date there are no studies in the HIV infected population The aim of our study is to in…
Synergistic effect of recombinant CD4-immunoglobulin in combination with azidothymidine, dideoxyinosine and 0.5 beta-monoclonal antibody on human imm…
1994
Data are presented which indicate that combinations of rCD4 immunoglobulin with azidothymidine, dideoxyinosine or 0.5 beta mouse monoclonal antibodies directed against the V3 region of HIV-1, were more effective in treatment of acute HIV infection in vitro than each compound alone. It is suggested that combination therapy with these compounds is more beneficial in treatment of HIV-infected patients than monotherapy, especially with respect to a reduction of the known side effects and the formation of resistant HIV strains after treatment with nucleoside analogues.
Molecular Classification of N-Aryloxazolidinone-5-carboxamides as Human Immunodeficiency Virus Protease Inhibitors
2015
Algorithms for classification and taxonomy are proposed in this chapter based information entropy (IE) and its production. The 38 N- aryloxazolidinone-5-carboxamides (NCAs), for human immunodeficiency virus (HIV) protease (PR) inhibition, are classified using seven characteristic chemical properties of different moieties: R 1/2 , R 3–6 on different phenyls and R 7 . Many classification algorithms are based on IE. When applying some procedures to moderate-sized sets, excessive number of results appear compatible with the data and suffer combinatorial explosion. However, after the equipartition conjecture (EC), one has a selection criterion among different variants that results from classifi…