Search results for "HMI"

Effects of amsacrine (m-AMSA), a new aminoacridine antitumor drug, on the rabbit heart.

1983

There is emerging clinical evidence that amsacrine (m-AMSA) administration may be associated with cardiotoxic effects such as severe, even fatal, ventricular arrhythmias and impairment of the inotropic performance of the heart. Information on the cardiac effects of m-AMSA in animals is scanty. Studies on mice, dogs, and monkeys have not evidenced the cardiotoxicity of the compound. The data presented in this paper show that m-AMSA causes acute ECG alterations in normal rabbits and a dose-related negative inotropic effect on the isolated rabbit heart, suggesting that this species may be a useful model for the study of the cardiac actions of this antiblastic.

Application of a Novel Refinement Method for Accurate Determination of Chemical Diffusion Coefficients in Electroactive Materials by Potential Step T…

2005

We describe application of a novel refinement method for an accurate determination of the chemical diffusion coefficient, D, and the generalized kinetic parameter, A, from experimental potentiostatic intermittent titration technique (PITT) data suited for a variety of electrochemically doped electroactive polymers and inorganic intercalation host materials. The proposed, simple, two-step refinement procedure, based on earlier derived analytical expressions for the PITT response, is exemplified by the analysis of chronoamperometric responses to small-amplitude potential perturbation for p- and n-doped poly(fluorenone-bithiophene) (PFDOBT-HH) thin film electrode. The initial p-doping and the …

Editorial: Current trends in the treatment of supraventricular tachycardia in pediatric age

2008

In pediatric age supraventricular tachiarrhythmias represent one of the most common cause of admission in cardiology units. Supraventricular arrhythmias may significantly influence the normal growth of a child with significant psycho-social implications. Pediatric cardiologists should be aware about the arrhythmias they face in their clinical practice. Moreover, they should know the possible risks related to specific arrhythmias and use the most efficacious therapeutic strategy with a correct knowledge of antiarrhythmic drugs. In this issue of Current Pharmacological Design the most recent knowledges on pathophysiology, diagnosis and treatment of supraventricular tachyarrhythmias in pediatr…

Normal forms of hyperbolic logarithmic transseries

2021

We find the normal forms of hyperbolic logarithmic transseries with respect to parabolic logarithmic normalizing changes of variables. We provide a necessary and sufficient condition on such transseries for the normal form to be linear. The normalizing transformations are obtained via fixed point theorems, and are given algorithmically, as limits of Picard sequences in appropriate topologies.

« Regards croisés sur le monument médiéval. Mélanges offerts à Claude Andrault-Schmitt, Marcello ANGHEBEN (dir.), Pierre MARTIN, Éric SPARHUBERT (col…

2019

Human Sociability in Antonio Montecatini's (1537–99) Commentary on Aristotle's Politics

2021

The present article delves into the history of political philosophy by discussing human sociability in Antonio Montecatini's (1537–99) commentary on Aristotle's Politics. The focus is on a philosophical analysis of three interrelated ideas that Montecatini discusses: (1) Aristotle's dictum that human beings are political animals by nature; (2) naturalness of the household; and (3) the nature and origin of political communities. Montecatini's views are briefly related to those of John Case (ca. 1546–1600), and they are also contextualized within the late medieval commentary tradition on the Politics, but the main aim is to clarify Montecatini's philosophical position and examine the ways in …

Comparative analysis in terms of computational cost for different discrimination algorithms in implantable defibrillators

2005

Implantable defibrillators (ICDs) use very low computational cost criteria (rate, stability and onset) offering good sensitivity for arrhythmia detection. Although, the specificity of these combined criteria decreases in difficult arrhythmia discrimination as in case of discrimination between ventricular tachycardia (VT) and supraventricular tachycardia (SVT). Several morphological published algorithms enhance arrhythmia discrimination but most algorithms are developed in personal computers and cannot be used in ICDs because of computational cost requirements compared with limited ICD capabilities. A general method to determine the possibility of ICD implementation for a discrimination algo…

Mathematical Model of Solid Food Pasteurization by Ohmic Heating: Influence of Process Parameters

2013

Pasteurization of a solid food undergoing ohmic heating has been analysed by means of a mathematical model, involving the simultaneous solution of Laplace’s equation, which describes the distribution of electrical potential within a food, the heat transfer equation, using a source term involving the displacement of electrical potential, the kinetics of inactivation of microorganisms likely to be contaminating the product. In the model, thermophysical and electrical properties as function of temperature are used. Previous works have shown the occurrence of heat loss from food products to the external environment during ohmic heating. The current model predicts that, when temperature gradient…

Safety and feasibility of atropine added in patients with sub-maximal heart rate during exercise myocardial perfusion SPECT.

2006

Failure to reach 80% of maximal predicted heart rate (HR) during exercise may render a myocardial perfusion single photon emission computed tomography (SPECT) study non-diagnostic for ischemia detection. We sought to investigate the injection of atropine in patients who fail to achieve 80% of age-predicted HR during exercise performed for myocardial perfusion SPECT (MPS), defining its safety and efficacy to raise HR to adequate levels as well as its effect on MPS interpretation.Between January 2002 and December 2004, we studied 3,150 consecutive patients (2,253 men and 897 women, mean age 55 +/- 6 years) who were referred to a single office-based nuclear cardiology laboratory for MPS using …

The Relevance of Kneading and Extrusion Parameters in the Manufacture of Active Porous Aluminas from Pseudoboehmites

1987

In order to study the effect-on crushing strength, attrition resistance, specific pore volume, and pore volume distribution of extrudates-of kneading and extrusion parameters in the manufacture of active porous aluminas, a commercial pseudoboehmite (Pural SB from Condea Chemie, Brunsbuttel, FRG) was employed. A minimum kneading torque was required to prepare an extrudable paste, predetermined by extrusion conditions. The torque had an upper limit with respect to certain extrudate properties. The amount of water and the concentration of nitric acid as binder solutions were found to have a decisive bearing on the mechanical properties and the distribution of the pore volume. Crushing strength…