Search results for "HT"
showing 10 items of 20594 documents
Maximal function estimates and self-improvement results for Poincaré inequalities
2018
Our main result is an estimate for a sharp maximal function, which implies a Keith–Zhong type self-improvement property of Poincaré inequalities related to differentiable structures on metric measure spaces. As an application, we give structure independent representation for Sobolev norms and universality results for Sobolev spaces. peerReviewed
Right Heart Dysfunction and Readmission Risk Across Left Ventricular Ejection Fraction Status in Patients With Acute Heart Failure.
2021
BACKGROUND: Right heart dysfunction (RHD) parameters are increasingly important in heart failure (HF). This study aimed to evaluate the association of advanced RHD with the risk of recurrent admissions across the spectrum of left ventricular ejection fraction (LVEF). METHODS AND RESULTS: We included 3383 consecutive patients discharged for acute HF. Of them, in 1435 patients (42.4%), the pulmonary artery systolic pressure could not be measured accurately, leaving a final sample size of 1948 patients. Advanced RHD was defined as the combination of a ratio of tricuspid annular plane systolic excursion/pulmonary artery systolic pressure of less than 0.36 and significant tricuspid regurgitation…
A bibliometric analysis of cultural heritage research in the humanities: The Web of Science as a tool of knowledge management
2023
AbstractSubstantial research on the topic of cultural heritage has been conducted over the past two decades. At the same time, the overall output volume of journals and citation metrics have become important parameters in assessing and ranking researchers’ performance. Even though the scholarly interest in cultural heritage has recently increased world-wide, a comprehensive analysis of the publication output volume and its correlation to the shift in the cultural heritage regime starting in 2003 is still lacking. The article aims to understand the role of Web of Science (WOS) as a tool of knowledge management in academia by drawing on the scholarly output volume, the patterns displayed by t…
Sosiomateriaalinen näkökulma vuorovaikutukseen muuttuvissa työtiloissa
2022
Työelämään ja organisaatioihin ovat viime vuosina vaikuttaneet monet eri muutokset. Yksi voimakkaimmista muutoksista koskee sitä, missä töitä tehdään eli työnteon tiloja. Tutkimuksissa on tarkasteltu muun muassa tilojen roolia ihmisten välisen vuorovaikutuksen edistämisessä, työntekijöiden oppimisen tukemisessa sekä inklusiivisuuden ja monimuotoisuuden vahvistamisessa. Viime aikoina huomiota on kiinnitetty erityisesti siihen, miten tilat vaikuttavat ihmisten toimijuuteen eli kykyyn ja mahdollisuuksiin toimia tai vaikuttaa erilaisiin työhön liittyviin tilanteisiin. Tässä puheenvuorossa keskityn siihen, miten tilojen ja ihmistoimijuuden välistä suhdetta voidaan tutkia niin kutsutusta sosiomat…
The effect of longitudinal chromatic aberration on the lag of accommodation and depth of field.
2016
Purpose Longitudinal chromatic aberration is present in all states of accommodation and may play a role in the accommodation response and the emmetropisation process. We study the change of the depth of field (DOFi) with the state of accommodation, taking into account the longitudinal chromatic aberration. Methods Subjective DOFi was defined as the range of defocus beyond which the blur of the target (one line of optotypes of 0.1 logMAR shown on a black-and-white microdisplay, seen through different colour filters) was perceived as objectionable. The subject's eye was paralysed and different, previously-measured accommodative states (corresponding to the accommodative demands of 0D, 2D and …
Volver al sentido de la ciudad. Reflexiones hermenéuticas y éticas
2020
El propósito de esta contribución es delinear las principales reflexiones sobre la ética de ciudad surgidas en los últimos años. Para ello se abordan, en primer lugar, las conexiones entre racionalidad práctica, urbanismo y espacio público desde la perspectiva del pragmatismo crítico y de la ciencia social fronética. Estas propuestas nos proporcionan el marco hermenéutico para presentar a continuación algunas de las aproximaciones éticas más relevantes que pueden aplicarse a las ciudades actuales: la ética de las virtudes urbanas, el derecho a la ciudad, el movimiento de la ciudad justa, el giro urbano de la ética, la ética del ambiente construido, la ética del diseño y la conducta medioamb…
Oscillatory Dynamics Underlying Perceptual Narrowing of Native Phoneme Mapping from 6 to 12 Months of Age
2016
During the first months of life, human infants process phonemic elements from all languages similarly. However, by 12 months of age, as language-specific phonemic maps are established, infants respond preferentially to their native language. This process, known as perceptual narrowing, supports neural representation and thus efficient processing of the distinctive phonemes within the sound environment. Although oscillatory mechanisms underlying processing of native and non-native phonemic contrasts were recently delineated in 6-month-old infants, the maturational trajectory of these mechanisms remained unclear. A group of typically developing infants born into monolingual English families, …
Power profiles in multifocal contact lenses with variable multifocal zone
2016
BACKGROUND The power profile of multifocal contact lenses has been demonstrated to report important information that could be used during the fitting process. The aim of this work is to describe the power profile of a recent set of gas permeable multifocal contact lenses as a function of the pupil radius. METHODS The measured multifocal contact lenses have a centre-distance design, and are available with five distance-vision diameters (XS, S, M, L and XL) and two different additions: Type A (up to +2.00 D) and Type B (up to +2.50 D). The optical device NIMO TR1504 (Lambda-X, Nivelles, Belgium) was used to obtain the power profile measurements. The optical lens power distribution as a functi…
New tricyclic systems as photosensitizers towards triple negative breast cancer cells.
2022
AbstractNineteen pyrrolo[1,2-h][1,7]naphthyridinones and pyrido[2,3-c]pyrrolo[1,2-a]azepinones were synthesized as new tricyclic systems in which the pyridine ring is annelated to the 6,7-dihydroindolizin-8(5H)-one and 5,6,7,8-tetrahydro-9H-pyrrole[1,2-a]azepine-9-one moieties to obtain potential photosensitizing agents. They were tested for their photoantiproliferative activity on a triple-negative breast cancer cell line, MDA-MB-231, in the dark and under UVA light (2.0 J/cm2). We demonstrated that their toxicity, only when exposed to light, was primarily due to the generation of reactive oxygen species while their photodegradation products were not responsible for their activity. The mos…
Väitöskirjatutkijat akateemisessa maailmassa
2022
Artikkelissa tarkastellaan akateemisen maailman reunaehtoja, joihin väitöskirjatutkijat törmäävät tohtoriopinnoissa sekä sitä, millaisia erilaisia polkuja asiantuntijuuteen reunaehdot viitoittavat. Tohtorikoulutusta asiantuntijuuden rakentumisen kontekstina on aiemmin tarkasteltu eri osa-alueiden, kuten ohjauksen tai rahoituksen, näkökulmasta. Sen sijaan tässä artikkelissa tavoittelemamme holistinen, yksilöllisiä ja systeemisiä ehtoja yhdistävä tarkastelu on ollut vähäistä. Tutkimuksen aineisto koostuu Tietoarkiston avulla kerätyistä väitöskirjatutkijoiden (N = 54) kirjoitelmista, joissa he kuvaavat kokemuksiaan asiantuntijana toimimiseen sisältyvistä mahdollisuuksista ja haasteista. Aineis…