Search results for "HTL"

showing 2 items of 62 documents

Interleukin-6 production in "normal" and HTLV-1 tax-expressing brain-specific endothelial cells.

1993

Abnormal cytokine production can contribute in many instances to the development of pathology. Our study focuses on the regulation of interleukin (IL)-6 production in vitro in brain-specific endothelial cells (BEC) under physiological conditions and in a model of human T leukemia virus-1 (HTLV-1) infection. IL-6 production was strongly up-regulated in a dose-dependent mode upon exposure to recombinant IL-1 beta, although nearly not detectable in unstimulated BEC. This induction of IL-6 production could be achieved by reagents known to increase intracellular levels of cAMP, such as forskolin, prostaglandin E or pentoxifylline. Furthermore, transcription and production of IL-6 was inducible b…

medicine.medical_specialtymedicine.medical_treatmentImmunologyTransfectionchemistry.chemical_compoundMiceInternal medicinemedicineImmunology and AllergyAnimalsRNA MessengerInterleukin 6health care economics and organizationsCells CulturedMice Inbred BALB CForskolinbiologyInterleukin-6Genes pXInterleukinBrainTransfectionHTLV-I InfectionsCell biologyEndothelial stem cellCytokineEndocrinologychemistryBucladesineSecond messenger systembiology.proteinEndothelium VascularProstaglandin EEuropean journal of immunology
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Jet fragmentation transverse momentum distributions in pp and p-Pb collisions at √s, √sNN = 5.02 TeV

2021

Jet fragmentation transverse momentum (jT) distributions are measured in proton-proton (pp) and proton-lead (p-Pb) collisions at √sNN = 5.02 TeV with the ALICE experiment at the LHC. Jets are reconstructed with the ALICE tracking detectors and electromagnetic calorimeter using the anti-kT algorithm with resolution parameter R = 0.4 in the pseudorapidity range |η| < 0.25. The jT values are calculated for charged particles inside a fixed cone with a radius R = 0.4 around the reconstructed jet axis. The measured jT distributions are compared with a variety of parton-shower models. Herwig and Pythia 8 based models describe the data well for the higher jT region, while they underestimate the low…

related to the perturbative component of the fragmentation processthe measured trends are successfully described by all models except for Herwig. For the wide componentHerwig and PYTHIA 8 based models slightly underestimate the data for the higher jet transverse momentum region. These measurements set constraints on models of jet fragmentation and hadronisation.Nuclear and High Energy Physicswhile that of the inverse gamma function increases with increasing jet transverse momentum. For the narrow componentHeavy Ion Experimentsand with a Gaussian for lower jT values (called the “narrow component”)hiukkasfysiikkawhile they underestimate the lower jT region. The jT distributions are further characterised by fitting them with a function composed of an inverse gamma function for higher jT values (called the “wide component”)predominantly connected to the hadronisation process. The width of the Gaussian has only a weak dependence on jet transverse momentumJet fragmentation transverse momentum (jT) distributions are measured in proton-proton (pp) and proton-lead (p-Pb) collisions at √sNN = 5.02 TeV with the ALICE experiment at the LHC. Jets are reconstructed with the ALICE tracking detectors and electromagnetic calorimeter using the anti-kT algorithm with resolution parameter R = 0.4 in the pseudorapidity range |η| < 0.25. The jT values are calculated for charged particles inside a fixed cone with a radius R = 0.4 around the reconstructed jet axis. The measured jT distributions are compared with a variety of parton-shower models. Herwig and PYTHIA 8 based models describe the data well for the higher jT region
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