Search results for "HUMAN HEALTH"
showing 10 items of 1622 documents
The relationship between persons with mental health problems and their dogs: A qualitative study within a nursing perspective
2013
Background: There is an increasing number of people with mental health disorders in the Western world. The most common traditional therapies are conversational therapy and medications. One alternative to traditional therapies is Anthrozoology. Anthrozoology treats the interaction between people and animals, and it shows that animals can be a great contributor to human health and wellness. Purpose: The purpose of this study was to examine how people with mental health disorders experience owning a dog. Methods: The chosen design was qualitative, and the methods were interviews and observations of five informants with their dogs. The analysis was conducted with systematic text-condensation. R…
Comment on: Tocilizumab induces corticosteroid sparing in rheumatoid arthritis patients in clinical practice: reply
2015
Type de document : lettre à l'éditeur; International audience
Oral health and adherence to national dietary guidelines in France
2017
International audience
New Perspective in Atrial Fibrillation
2020
International audience; Despite a large number of publications on this subject, the pathophysiological mechanisms involved in atrial fibrillation (AF) onset and recurrence are uncertain [...]
The LDL receptor in the retina: the missing link in aging, the new target in dietary prevention
2012
National audience; Purpose: The discovery of the LDL receptor (LDLR) in 1985 by Brown and Goldstein was awarded by a Nobel Prize. The LDLR has initially been identified for its role in mediating the endocytosis of LDL particles in the vascular endothelium. The deposition of lipids, including cholesterol and cholesteryl esters in Bruch’s Membrane in the one hand, and in the vessel intima in the other hand, is one of the common features of age related macular degeneration (AMD) and cardiovascular disease (CVD). Dietary habits with high intakes of omega 3 long chain fatty acids (LCFA) have been associated with AMD prevention. Similar effects have been demonstrated in CVD prevention. The mechan…
Fructose diet induced short-term impairment of cone sensitivity and gene expression in rat retina
2012
National audience; Abstract: Purpose A high fructose diet has been widely used to trigger insulin resistance in rodent; insulin resistance is one of the major risk factor for the development of type 2 diabetes. Thirty to 40% of diabetic patients develop diabetic retinopathy. In this study, we aimed to evaluate the short-term effect, at 1, 3, 5, 8 days, of a 60% fructose diet, on photoreceptor sensitivity and gene expression in the retina of Brown Norway rats. Methods: Flicker electroretinograms (8Hz) were recorded under anesthesia, from both eyes simultaneously in order to study sensitivity of photoreceptors. Then, rats were euthanized and enucleated. Retinae and posterior poles were collec…
Combined effects of aging and a pro-diabetic diet on retinal function in a murine model of aging of the human eye
2009
; Purpose: Improvement of life expectancy and changes in the dietary behaviour of developed populations are accompanied with the prevalence of diabetes and age-related ocular pathologies. Aging of the retina is characterized by accumulation of lipids at the basement of the retinal pigment epithelium - Bruch’s membrane complex.Meanwhile increased oxidative stress is one of the features of aging and diabetes. A fructose-rich diet induces insulin resistance and hypertriglyceridemia, mimicking diabetes. The goal of our study was to evaluate the effects of a pro-diabetic fructose-enriched diet on the retinal function of the ApoB100,LDLR-/- mice, a murine model of aging of the human eye. Methods…
Maintenance of anticoagulant and antiplatelet agents for patients undergoing vitreoretinal surgery
2010
International audience; Purpose: To establish the prevalence of anticoagulant, aspirin, and clopidogrel use in patients undergoing vitreoretinal surgery, and to compare the outcome of peribulbar anesthesia between users and non‐users. Methods: We conducted a retrospective case series in one academic center between January and June 2009. We analyzed the chart of 239 eyes who underwent posterior segment surgery with peribulbar anesthesia. No changes in the anticoagulant regimen were made prior to surgery. We divided patients into 7 groups: group 1: patients with no anticoagulants and 6 groups defined according to the type of anticoagulant or antiplatelet medication. Results: 239 eyes (206 pat…
Role of biomarkers in the management of antibiotic therapy : an expert panel review : I - currently available biomarkers for clinical use in acute in…
2013
Abstract In the context of worldwide increasing antimicrobial resistance, good antimicrobial prescribing in more needed than ever; unfortunately, information available to clinicians often are insufficient to rely on. Biomarkers might provide help for decision-making and improve antibiotic management. The purpose of this expert panel review was to examine currently available literature on the potential role of biomarkers to improve antimicrobial prescribing, by answering three questions: 1) Which are the biomarkers available for this purpose?; 2) What is their potential role in the initiation of antibiotic therapy?; and 3) What is their role in the decision to stop antibiotic therapy? To ans…
Similarly increased congenital anomaly rates after intrauterine insemination and IVF technologies: a retrospective cohort study
2012
International audience; BACKGROUND: While intrauterine insemination (IUI), a simple, inexpensive and non-invasive technique, is the most used assisted reproduction technology (ART) worldwide, the risk of major birth defects following IUI is paradoxically not well documented. METHODS: Retrospective cohort study performed in Burgundy, France, over a 9-year period which consisted of the cross analysis of two prospective databases, the Burgundy perinatal network database and the database of the assisted conception units in Burgundy. A total of 1348 ART singletons [in vitro fertilization technologies (IVFT): n= 903; IUI: n= 445] matched with 4044 infants conceived naturally, 552 ART twins (IVFT:…