Search results for "HV"
showing 10 items of 353 documents
Ohjaava koulutus yksilön vahvistajana : esimerkkinä Oman Elämän Valtias -koulutus ja Kontti-työjakso
2006
Distinctive Patterns of Intraclonal Diversification In IGHV1-2*04 Immunoglobulin Receptors of Patients with Splenic Marginal Zone Lymphoma: A of Ongo…
2011
Abstract Abstract 2638 We recently demonstrated that over 30% of cases with splenic marginal-zone lymphoma (SMZL) express distinctive immunoglobulin (IG) receptors that utilize a single polymorphic variant of the IGHV1-2 gene (IGHV1-2*04) and also exhibit restricted antigen-binding site motifs and precise targeting of somatic hypermutation (SHM). On these grounds, we proposed the existence of molecular subtypes of SMZL defined by immunogenetic analysis of the IG receptors with implications for selection by specific (super) antigenic element(s) in the development of at least a major subset of SMZL. In order to gain insight as to whether antigen involvement is relevant only prior to the malig…
Optimization of hybrid – ground coupled and air source – heat pump systems in combination with thermal storage
2010
Ground coupled heat pumps are attractive solutions for cooling and heating commercial buildings due to their high efficiency and their reduced environmental impact. Two possible ideas to improve the efficiency of these systems are decoupling energy generation from energy distribution and combining different HVAC systems. Based on these two ideas, we present several HVAC configurations which combine the following equipments: a ground coupled heat pump, an air to water heat pump and a thermal storage device. These HVAC configurations are linked to an office building in a cooling dominated area in order to evaluate in these conditions the total electrical consumption of each configuration to o…
The ECHR Condemns Prison Overcrowding in Italy: The Total Reorganization of the Institution and the Social Reintegration of the Prisoner
2017
The contribution analyses the current Italian prison system, which has been called upon on to resolve its structural problems. The Council of Europe, in fact, in 2013 condemned Italy for inhuman treatment in its prisons. The principal accusation concerns the problem of overcrowding. The country has responded with solutions such as the application of the open system, which provides cells solely for overnight stays, and dynamic monitoring, an effective system for ensuring order in the institutions. These initiatives aim to promote re-educational activities and the social re-integration of prisoners. In addition, Italian institutions have made greater use of alternatives to custodial penalties…
Do we value mobility?
2015
Is there a trade-off between people's preference for income equality and income mobility? Testing for the existence of such a trade-off is difficult because mobility is a multifaceted concept. We analyse results from a questionnaire experiment based on simple precise concepts of income inequality and income mobility. We fnd no direct trade-off in preference between mobility and equality, but an indirect trade-off, applying when more income mobility can only be obtained at the expense of some income inequality. Mobility preference - but not equality preference - appears to be driven by personal experience of mobility.
Täpläravun (Pacifastacus leniusculus) vaikutus ahventen (Perca fluviatilis) loisyhteisöihin Päijänteellä
2010
Täplärapu (Pacifastacus leniusculus) on tulokaslaji Suomen vesistöissä. Sen on käyttäytymisellään ja ravinnonkäytöllään todettu vähentävän elinalueidensa eliöyhteisöjen monimuotoisuutta. Esimerkiksi Päijänteellä on havaittu joidenkin pohjaeläinten kuten kotiloiden tiheyksien olevan alhaisempia ravun elinalueilla kuin ravuttomilla alueilla. Pohjaselkärangattomat ovat välttämättömiä väli-isäntiä monelle kalan loiselle. Tässä tutkimuksessa selvitettiin, millaisia muutoksia täplärapu voi välillisesti aiheuttaa kalojen loisyhteisöissä muuttamalla pohjaeläinten runsautta. Päijänteeltä valittiin viisi toisistaan riippumatonta ravullista ja ravutonta aluetta. Jokaiselta alueelta pyydettiin mahdolli…
Insufficient Antigen Presentation Due to Viral Immune Evasion Explains Lethal Cytomegalovirus Organ Disease After Allogeneic Hematopoietic Cell Trans…
2020
Reactivation of latent cytomegalovirus (CMV) poses a clinical problem in transiently immunocompromised recipients of hematopoietic cell (HC) transplantation (HCT) by viral histopathology that results in multiple organ manifestations. Compared to autologous HCT and to syngeneic HCT performed with identical twins as HC donor and recipient, lethal outcome of CMV infection is more frequent in allogeneic HCT with MHC/HLA or minor histocompatibility loci mismatch between donor and recipient. It is an open question if a graft-versus-host (GvH) reaction exacerbates CMV disease, or if CMV exacerbates GvH disease (GvHD), or if interference is mutual. Here we have used a mouse model of experimental HC…
Over 30% of Patients with Splenic Marginal Zone Lymphoma Express Distinctive Antigen Receptors Utilizing a Single Immunoglogulin Variable Gene: Impli…
2010
Abstract Abstract 634 We systematically explored the immunoglobulin (IG) gene repertoire in 337 cases with splenic marginal-zone lymphoma (SMZL), by far the largest series yet. To resolve classification uncertainties, we included in the analysis only cases with a diagnosis of SMZL based on spleen histopathological findings or cases fulfilling the 2008 SBLG criteria (Matutes et al. Leukemia 2008). We here report that the IG heavy variable (IGHV) gene repertoire in SMZL is remarkably biased, with only three genes accounting for 45.8% of cases (IGHV1-2, 24.9%; IGHV4-34, 12.8%; IGHV3-23: 8.1%, respectively), significantly extending previous similar observations. Particularly for the IGHV1-2 gen…
PCB-Based Planar Inductive Loops for Partial Discharges Detection in Power Cables
2022
Partial discharge (PD) diagnosis tests, including detecting, locating, and identifying, are used to trace defects or faults and assess the degree of aging in order to monitor the insulation condition of medium- and high-voltage power cables. In this context, an experimental evaluation of three different printed circuit board (PCB)-based inductive sensor topologies, with spiral, non-spiral, and meander shapes, is performed. The aim is to assess their capabilities for PD detection along a transmission power cable. First, simulation and experimental characterization are carried out to determine the equivalent electrical circuit and the quality factor of the three sensors. PD activity was studi…
Lapsen vahvuudet esiopetusvuoden pedagogisissa asiakirjoissa
2019
Vahvuusperustainen kasvatusajattelu on saanut viime vuosina Suomessa paljon huomiota. Vahvuuksien hyödyntäminen tukee lasten itsearvostusta, lisää myönteistä käyttäytymistä ryhmässä ja voi helpottaa vaikeuksien ja epäonnistumisten sietämistä. Tässä tutkimuksessa tarkastelemme, millaisia vahvuuksia tehostettua tai erityistä tukea saavien lasten pedagogisissa asiakirjoissa kuvataan esiopetuksessa, miten vahvuuksista kirjoitetaan sekä millaisia tehtäviä lasten vahvuuksien kirjaamisella on. Tutkimuksen aineiston muodostavat esiopetuksen oppimissuunnitelmat, tehostetun tuen suunnitelmat ja HOJKS-asiakirjat (N = 65). Aineistolähtöisessä analyysissa vahvuuksiksi ymmärrettiin lapsen kyvyt, luonteen…